Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Mohamed E. Awad

TitleResearch Scientist
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-ORTHO General Operations

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Awad ME, Lev G, Melton DH, Shaw KG, Thomsen-Freitas PB, Gaffney BMM, Christiansen CL, Stoneback JW. Colorado Limb Donning-Timed Up and Go (COLD-TUG) Test in Lower-Extremity Amputation: Less Donning Time with Osseointegrated Bone-Anchored Prosthetic Limb. J Bone Joint Surg Am. 2025 May 13. PMID: 40359258.
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    2. Sajid MI, Grayson W, John MP, Taylor S, Lauck BJ, Zaidi Z, Savage A, Griffin N, Awad M, Chen AT, Hwang J, Alfonso N, Mir HR. Efficacy of Topical Antibiotic Powder Application in the Emergency Department on Reducing Deep Fracture-Related Infection in Type III Open Lower Extremity Fractures: A Multicenter Study. J Am Acad Orthop Surg. 2025 Apr 01. PMID: 40179368.
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    3. Shaw KG, Awad ME, Melton D, Gaffney BMM, Christiansen CL, Stoneback JW. Patient-Reported Outcomes of Pain and Related Quality of Life 1 Year After Bone-Anchored Limb Implantation in Patients with Lower-Limb Amputation. J Bone Joint Surg Am. 2025 Apr 16; 107(8):e32. PMID: 40014677.
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    4. Thomsen-Freitas PB, Stoneback JW, Tracy JB, Awad ME, Melton DH, Gaffney BMM, Christiansen CL. Altered cumulative joint moments and increased joint moment symmetry during sit-to-stand transitions for transfemoral bone-anchored limb users: A case series. Clin Biomech (Bristol). 2025 Apr; 124:106476. PMID: 40037117.
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    5. Epperson AB, Awad ME, Gorman M, Loker K, Alfonso NA, Stoneback JW. Clinical practice guidelines for antimicrobial-loaded cements and beads in orthopedic trauma and arthroplasty. Eur J Orthop Surg Traumatol. 2024 Nov 25; 35(1):25. PMID: 39585403.
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    6. Awad M, Taylor-Diaz E, Tawfik A, Hussein K, Elmansi A, Elashiry M, Elsayed R, Shahoumi L, Borke J, Hill W, Dong F, Elsalanty ME. Zoledronate interrupts pre-osteoclast-induced angiogenesis via SDF-1/CXCR4 pathway. Bone Rep. 2024 Dec; 23:101812. PMID: 39583183.
      View in: PubMed
    7. Hagan ML, Tuladhar A, Yu K, Alhamad DW, Bensreti H, Dorn J, Piedra VM, Cantu N, Stokes EG, Blumenthal D, Roberts RL, Balayan V, Bass SM, Dickerson T, Cartelle AL, Montesinos-Cartagena M, Awad ME, Castro AA, Garland T, Cooley MA, Johnson M, Hamrick MW, McNeil PL, McGee-Lawrence ME. Osteocyte Sptbn1 Deficiency Alters Cell Survival and Mechanotransduction Following Formation of Plasma Membrane Disruptions (PMD) from Mechanical Loading. Calcif Tissue Int. 2024 Nov; 115(5):725-743. PMID: 39276238.
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    8. Awad ME, Griffin NA, Epperson AB, Alfonso NA, Ou-Yang D. Extended Postoperative Antibiotic Prophylaxis Is Associated with No Clinical Value and Higher Projected Cost Following Adult Spinal Surgery: A Stratified Meta-Analysis and Probability-Based Cost Projections. JBJS Rev. 2024 Sep 01; 12(9). PMID: 39226392.
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    9. Tracy JB, Gaffney BMM, Thomsen PB, Awad ME, Melton DH, Christiansen CL, Stoneback JW. Dynamic gait stability and stability symmetry for people with transfemoral amputation: A case-series of 19 individuals with bone-anchored limbs. J Biomech. 2024 Jun; 171:112208. PMID: 38941842.
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    10. Thomsen PB, Gaffney BMM, Tracy JB, Vandenberg NW, Awad ME, Christiansen CL, Stoneback JW. Cumulative loading increases and loading asymmetries persist during walking for people with a transfemoral bone-anchored limb. Gait Posture. 2024 Sep; 113:46-52. PMID: 38843706.
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    11. Vinson AL, Vandenberg NW, Awad ME, Christiansen CL, Stoneback JW, M M Gaffney B. The biomechanical influence of transtibial Bone-Anchored limbs during walking. J Biomech. 2024 May; 168:112098. PMID: 38636112.
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    12. Awad ME, Melton D, Shaw KG, Lev G, Gaffney BMM, Christiansen CL, Stoneback JW. How Comprehensive and Efficient Are Patient-Reported Outcome Measures for Individuals with Lower Extremity Amputation Undergoing Implantation of Osseointegrated Bone Anchored Limbs? JBJS Rev. 2024 Mar 01; 12(3). PMID: 38489397.
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    13. Richman EH, Richman OT, Lee MS, Qubain L, Heylmun L, Awad ME, Alfonso N. Social Media and Digital Footprints in Orthopaedic Trauma: An Analysis of 1465 Orthopaedic Trauma Association Members. J Orthop Trauma. 2024 01 01; 38(1):e36. PMID: 37559214.
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    14. Pearl A, Awad ME, Hasan AI, Saleh KJ. Antimicrobial Incise Drapes in Knee and Hip Arthroplasties: Meta-analysis of Randomized Controlled and Prospective Cohort Studies. J Surg Orthop Adv. 2024; 33(4):206-211. PMID: 39644283.
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    15. Roda GF, Awad ME, Melton DH, Christiansen CL, Stoneback JW, Gaffney BMM. The Amputated Limb Gluteus Medius is Biomechanically Disadvantaged in Patients with Unilateral Transfemoral Amputation. Ann Biomed Eng. 2024 Mar; 52(3):565-574. PMID: 37946055.
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    16. Awad ME, Chung JY, Griffin N, Stoneback JW, Alfonso NA. Prophylactic Intrawound Antibiotics Significantly Reduce the Risk of Deep Infections in Fracture Fixation: Subgroup Meta-analyses of the Type of Fracture, Antibiotics, and Organism. J Orthop Trauma. 2023 10 01; 37(10):e400-e409. PMID: 37296086.
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    17. Vandenberg NW, Stoneback JW, Davis-Wilson H, Christiansen CL, Awad ME, Melton DH, Gaffney BMM. Unilateral transfemoral osseointegrated prostheses improve joint loading during walking. J Biomech. 2023 06; 155:111658. PMID: 37276681.
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    18. Jarrahi A, Khodadadi H, Moore NS, Lu Y, Awad ME, Salles EL, Vaibhav K, Baban B, Dhandapani KM. Recombinant human DNase-I improves acute respiratory distress syndrome via neutrophil extracellular trap degradation. J Thromb Haemost. 2023 09; 21(9):2473-2484. PMID: 37196848.
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    19. Gaffney BMM, Davis-Wilson HC, Awad ME, Tracy J, Melton DH, Lev G, Stoneback JW, Christiansen CL. Daily steps and stepping cadence increase one-year following prosthesis osseointegration in people with lower-limb amputation. Disabil Rehabil. 2024 Apr; 46(7):1432-1437. PMID: 37073780.
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    20. Gendya AGMK, El-Zaher EH, Zakaria ZM, Awad MES, Metwaly RGEA. Double Plating Fixation vs Distal Femoral Replacement in the Management of Distal Femoral Fractures in Geriatric Patients. Arthroplast Today. 2023 Apr; 20:101113. PMID: 36949829.
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    21. Zhang Z, Huang Z, Awad M, Elsalanty M, Cray J, Ball LE, Maynard JC, Burlingame AL, Zeng H, Mansky KC, Ruan HB. O-GlcNAc glycosylation orchestrates fate decision and niche function of bone marrow stromal progenitors. Elife. 2023 03 02; 12. PMID: 36861967.
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    22. Roldan M, Awad ME, VanAken TD, Saasouh W, Patel P, Mostafa G, Saleh KJ. Sub-chondroplasty Reduces Pain, Improves Function and Delays the Conversion to Arthroplasty in Patients with Advanced Knee Osteoarthritis: A Stratified Meta-analysis and Quality Assessment. J Surg Orthop Adv. 2023; 32(2):65-74. PMID: 37668640.
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    23. Farley BJ, Awad ME, Anderson P, Esseili AS, Hruska J, Mostafa G, Saleh KJ. Opioid-Related Genetic Polymorphisms of Cytochrome P450 Enzymes after Total Joint Arthroplasty: A Focus on Drug-Drug-Gene Interaction with Commonly Coprescribed Medications. Orthop Clin North Am. 2022 Oct; 53(4):361-375. PMID: 36208880.
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    24. Hijazi A, Hasan A, Pearl A, Memon R, Debeau M, Roldan M, Awad ME, Abdul-Kabir E, Saleh KJ. Genetic Polymorphisms Associated with Perioperative Joint Infection following Total Joint Arthroplasty: A Systematic Review and Meta-Analysis. Antibiotics (Basel). 2022 Sep 02; 11(9). PMID: 36139966.
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    25. Irfan FB, Minetti R, Telford B, Ahmed FS, Syed AY, Hollon N, Brauman SC, Cunningham W, Awad ME, Saleh KJ, Waljee AK, Brusselaers N. Coronavirus pandemic in the Nordic countries: Health policy and economy trade-off. J Glob Health. 2022 Aug 08; 12:05017. PMID: 35932219.
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    26. Baldawi M, Awad ME, McKelvey G, Pearl AD, Mostafa G, Saleh KJ. Neuraxial Anesthesia Significantly Reduces 30-Day Venous Thromboembolism Rate and Length of Hospital Stay in Primary Total Hip Arthroplasty: A Stratified Propensity Score-Matched Cohort Analysis. J Arthroplasty. 2023 Jan; 38(1):108-116. PMID: 35843379.
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    27. Awad ME, Farley BJ, Mostafa G, Darwiche HF, Saleh KJ. The risk of hospital readmission, revision, and intra- and postoperative complications between direct anterior versus posterior approaches in primary total hip arthroplasty: a stratified meta-analysis and a probability based cost projection. Hip Int. 2023 May; 33(3):442-462. PMID: 35437055.
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    28. Crespi Z, Hasan AI, Pearl A, Ismail A, Awad ME, Irfan FB, Jaffar M, Patel P, Saleh KJ. Current Guidelines and Practice Recommendations to Prevent Hospital-Acquired Conditions After Major Orthopaedic Surgeries. JBJS Rev. 2022 03 15; 10(3). PMID: 35290253.
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    29. Elhaddad A, Awad M, Shehata SM, Shehata MA. Laparoscopic management of infantile hydrocele in pediatric age group. Pediatr Surg Int. 2022 Apr; 38(4):581-587. PMID: 35124724.
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    30. Elhage KG, Awad ME, Irfan FB, Lumbley J, Mostafa G, Saleh KJ. Closed-incision negative pressure therapy at -125?mmHg significantly reduces surgical site complications following total hip and knee arthroplasties: A stratified meta-analysis of randomized controlled trials. Health Sci Rep. 2022 Jan; 5(1):e425. PMID: 35229037.
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    31. Elshimy A, Osman AM, Awad MES, Abdel Aziz MM. Diagnostic accuracy of point-of-care knee ultrasound for evaluation of meniscus and collateral ligaments pathology in comparison with MRI. Acta Radiol. 2023 Jul; 64(7):2283-2292. PMID: 34851172.
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    32. Eldahshan W, Sayed MA, Awad ME, Ahmed HA, Gillis E, Althomali W, Pillai B, Alshammari A, Jackson L, Dong G, Sullivan JC, Cooley MA, Elsalanty M, Ergul A, Fagan SC. Stimulation of angiotensin II receptor 2 preserves cognitive function and is associated with an enhanced cerebral vascular density after stroke. Vascul Pharmacol. 2021 12; 141:106904. PMID: 34481068.
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    33. Crespi Z, Ismail A, Awad ME, Hasan AI, Irfan FB, Jaffar M, El-Othmani MM, Saleh KJ. Hospital-Acquired Conditions: A Review of Classical and Novel Risk Factors Following Total Hip and Knee Arthroplasties. JBJS Rev. 2021 07 16; 9(7). PMID: 34270501.
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    34. Awad ME, Farley BJ, Mostafa G, Saleh KJ. Direct anterior approach has short-term functional benefit and higher resource requirements compared with the posterior approach in primary total hip arthroplasty : a meta-analysis of functional outcomes and cost. Bone Joint J. 2021 Jun; 103-B(6):1078-1087. PMID: 34058867.
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    35. Cain M, Awad ME, Kolhe R, Mondal AK, Ghilzai U, Isales C, Fulcher M, Fulzele S. Dysregulation of epigenetic related genes in Diabetic Trigger finger Patients; preliminary analysis of Patient-Derived Samples. Biomol Concepts. 2020 Dec 31; 11(1):221-229. PMID: 34233433.
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    36. Shehata SM, Elgendy A, Elhaddad AA, Awad ME, Shalaby MM, AboElyazeed AM. Homemade Glove Retrieval Bag in Laparoscopic Complete Excision of Benign Ovarian Teratoma with Ovarian Tissue Preservation in Children: A Case Series. J Pediatr Adolesc Gynecol. 2020 Dec; 33(6):712-714. PMID: 32781234.
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    37. Awad ME, Rumley JCL, Vazquez JA, Devine JG. Perioperative Considerations in Urgent Surgical Care of Suspected and Confirmed COVID-19 Orthopaedic Patients: Operating Room Protocols and Recommendations in the Current COVID-19 Pandemic. J Am Acad Orthop Surg. 2020 Jun 01; 28(11):451-463. PMID: 32282441.
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    38. Elsayed R, Kurago Z, Cutler CW, Arce RM, Gerber J, Celis E, Sultan H, Elashiry M, Meghil M, Sun C, Auersvald CM, Awad ME, Zeitoun R, Elsayed R, Eldin M Elshikh M, Isales C, Elsalanty ME. Role of dendritic cell-mediated immune response in oral homeostasis: A new mechanism of osteonecrosis of the jaw. FASEB J. 2020 02; 34(2):2595-2608. PMID: 31919918.
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    39. Hafez S, Khan MB, Awad ME, Wagner JD, Hess DC. Short-Term Acute Exercise Preconditioning Reduces Neurovascular Injury After Stroke Through Induced eNOS Activation. Transl Stroke Res. 2020 08; 11(4):851-860. PMID: 31858409.
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    40. Bollag AE, Guo T, Ding KH, Choudhary V, Chen X, Zhong Q, Xu J, Yu K, Awad ME, Elsalanty M, Johnson MH, McGee-Lawrence ME, Bollag WB, Isales CM. Monomethylfumarate protects against ovariectomy-related changes in body composition. J Endocrinol. 2019 Oct; 243(1):15-26. PMID: 31362266.
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    41. Awad ME, Sun C, Jernigan J, Elsalanty M. Serum C-terminal cross-linking telopeptide level as a predictive biomarker of osteonecrosis after dentoalveolar surgery in patients receiving bisphosphonate therapy: Systematic review and meta-analysis. J Am Dent Assoc. 2019 08; 150(8):664-675.e8. PMID: 31256803.
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    42. Sayeed Z, Anoushiravani AA, Simha S, Padela MT, Schafer P, Awad ME, Darwiche HF, Saleh KJ. Markers for Malnutrition and BMI Status in Total Joint Arthroplasty and Pharmaconutrient Therapy. JBJS Rev. 2019 May; 7(5):e3. PMID: 31094890.
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    43. Awad ME, Padela MT, Sayeed Z, El-Othmani MM, Zekaj M, Darwiche HF, Saleh KJ. Pharmacogenomic Testing for Postoperative Pain Optimization Before Total Joint Arthroplasty: A Focus on Drug-Drug-Gene Interaction with Commonly Prescribed Drugs and Prior Opioid Use. JBJS Rev. 2019 May; 7(5):e2. PMID: 31094889.
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    44. Awad ME, Hussein KA, Helwa I, Abdelsamid MF, Aguilar-Perez A, Mohsen I, Hunter M, Hamrick MW, Isales CM, Elsalanty M, Hill WD, Fulzele S. Meta-Analysis and Evidence Base for the Efficacy of Autologous Bone Marrow Mesenchymal Stem Cells in Knee Cartilage Repair: Methodological Guidelines and Quality Assessment. Stem Cells Int. 2019; 2019:3826054. PMID: 31089328.
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    45. Elmansi AM, Awad ME, Eisa NH, Kondrikov D, Hussein KA, Aguilar-P?rez A, Herberg S, Periyasamy-Thandavan S, Fulzele S, Hamrick MW, McGee-Lawrence ME, Isales CM, Volkman BF, Hill WD. What doesn't kill you makes you stranger: Dipeptidyl peptidase-4 (CD26) proteolysis differentially modulates the activity of many peptide hormones and cytokines generating novel cryptic bioactive ligands. Pharmacol Ther. 2019 06; 198:90-108. PMID: 30759373.
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    46. Awad ME, Altman A, Elrefai R, Shipman P, Looney S, Elsalanty M. The use of vascularized fibula flap in mandibular reconstruction; A?comprehensive systematic review and meta-analysis of the observational studies. J Craniomaxillofac Surg. 2019 Apr; 47(4):629-641. PMID: 30782453.
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    47. Salgueiro M, Stribos M, Zhang LF, Stevens M, Awad ME, Elsalanty M. Value of pre-operative CTX serum levels in the prediction of medication-related osteonecrosis of the jaw (MRONJ): a retrospective clinical study. EPMA J. 2019 Mar; 10(1):21-29. PMID: 30984311.
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    48. Singleton Q, Vaibhav K, Braun M, Patel C, Khayrullin A, Mendhe B, Lee BR, Kolhe R, Kaiser H, Awad ME, Fariyike T, Elsayed R, Elsalanty M, Isales CM, Liu Y, Hamrick MW, Dhandapani KM, Fulzele S. Bone Marrow Derived Extracellular Vesicles Activate Osteoclast Differentiation in Traumatic Brain Injury Induced Bone Loss. Cells. 2019 01 17; 8(1). PMID: 30658394.
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    49. Awad ME, Padela MT, Sayeed Z, Abaab L, El-Othmani MM, Saleh KJ. Pharmacogenomics Testing for Postoperative Pain Optimization Before Total Knee and Total Hip Arthroplasty. JBJS Rev. 2018 Oct; 6(10):e3. PMID: 30300249.
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    50. Kennon JC, Awad ME, Chutkan N, DeVine J, Fulzele S. Current insights on use of growth factors as therapy for Intervertebral Disc Degeneration. Biomol Concepts. 2018 May 19; 9(1):43-52. PMID: 29779014.
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    51. Bowman S, Awad ME, Hamrick MW, Hunter M, Fulzele S. Recent advances in hyaluronic acid based therapy for osteoarthritis. Clin Transl Med. 2018 Feb 16; 7(1):6. PMID: 29450666.
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    52. Elsayed R, Abraham P, Awad ME, Kurago Z, Baladhandayutham B, Whitford GM, Pashley DH, McKenna CE, Elsalanty ME. Removal of matrix-bound zoledronate prevents post-extraction osteonecrosis of the jaw by rescuing osteoclast function. Bone. 2018 05; 110:141-149. PMID: 29408511.
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    53. Khan MB, Hafez S, Hoda MN, Baban B, Wagner J, Awad ME, Sangabathula H, Haigh S, Elsalanty M, Waller JL, Hess DC. Chronic Remote Ischemic Conditioning Is Cerebroprotective and Induces Vascular Remodeling in a VCID Model. Transl Stroke Res. 2018 02; 9(1):51-63. PMID: 28755277.
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