Depressed pacemaker activity of sinoatrial node myocytes contributes to the age-dependent decline in maximum heart rate.
Larson ED, St Clair JR, Sumner WA, Bannister RA, Proenza C. Depressed pacemaker activity of sinoatrial node myocytes contributes to the age-dependent decline in maximum heart rate. Proc Natl Acad Sci U S A. 2013 Oct 29; 110(44):18011-6.