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Connection

Bruce Molitoris to Kidney Tubules, Proximal

This is a "connection" page, showing publications Bruce Molitoris has written about Kidney Tubules, Proximal.

 
Connection Strength
  
 
 
7.624
  
  1. Molitoris BA, Sandoval RM, Yadav SPS, Wagner MC. Albumin uptake and processing by the proximal tubule: physiological, pathological, and therapeutic implications. Physiol Rev. 2022 10 01; 102(4):1625-1667.
    View in: PubMed
    Score: 0.673
  2. Molitoris BA. DNA damage response protects against progressive kidney disease. J Clin Invest. 2019 11 01; 129(11):4574-4575.
    View in: PubMed
    Score: 0.569
  3. Wagner MC, Myslinski J, Pratap S, Flores B, Rhodes G, Campos-Bilderback SB, Sandoval RM, Kumar S, Patel M, Molitoris BA. Mechanism of increased clearance of glycated albumin by proximal tubule cells. Am J Physiol Renal Physiol. 2016 05 01; 310(10):F1089-102.
    View in: PubMed
    Score: 0.440
  4. Wagner MC, Campos-Bilderback SB, Chowdhury M, Flores B, Lai X, Myslinski J, Pandit S, Sandoval RM, Wean SE, Wei Y, Satlin LM, Wiggins RC, Witzmann FA, Molitoris BA. Proximal Tubules Have the Capacity to Regulate Uptake of Albumin. J Am Soc Nephrol. 2016 Feb; 27(2):482-94.
    View in: PubMed
    Score: 0.419
  5. Dickson LE, Wagner MC, Sandoval RM, Molitoris BA. The proximal tubule and albuminuria: really! J Am Soc Nephrol. 2014 Mar; 25(3):443-53.
    View in: PubMed
    Score: 0.380
  6. Sandoval RM, Wagner MC, Patel M, Campos-Bilderback SB, Rhodes GJ, Wang E, Wean SE, Clendenon SS, Molitoris BA. Multiple factors influence glomerular albumin permeability in rats. J Am Soc Nephrol. 2012 Mar; 23(3):447-57.
    View in: PubMed
    Score: 0.331
  7. Weinberg JM, Molitoris BA. Illuminating mitochondrial function and dysfunction using multiphoton technology. J Am Soc Nephrol. 2009 Jun; 20(6):1164-6.
    View in: PubMed
    Score: 0.276
  8. Molitoris BA, Dagher PC, Sandoval RM, Campos SB, Ashush H, Fridman E, Brafman A, Faerman A, Atkinson SJ, Thompson JD, Kalinski H, Skaliter R, Erlich S, Feinstein E. siRNA targeted to p53 attenuates ischemic and cisplatin-induced acute kidney injury. J Am Soc Nephrol. 2009 Aug; 20(8):1754-64.
    View in: PubMed
    Score: 0.276
  9. Sandoval RM, Molitoris BA. Quantifying endocytosis in vivo using intravital two-photon microscopy. Methods Mol Biol. 2008; 440:389-402.
    View in: PubMed
    Score: 0.251
  10. Yu W, Sandoval RM, Molitoris BA. Quantitative intravital microscopy using a Generalized Polarity concept for kidney studies. Am J Physiol Cell Physiol. 2005 Nov; 289(5):C1197-208.
    View in: PubMed
    Score: 0.211
  11. Ashworth SL, Wean SE, Campos SB, Temm-Grove CJ, Southgate EL, Vrhovski B, Gunning P, Weinberger RP, Molitoris BA. Renal ischemia induces tropomyosin dissociation-destabilizing microvilli microfilaments. Am J Physiol Renal Physiol. 2004 May; 286(5):F988-96.
    View in: PubMed
    Score: 0.190
  12. Sandoval RM, Molitoris BA. Gentamicin traffics retrograde through the secretory pathway and is released in the cytosol via the endoplasmic reticulum. Am J Physiol Renal Physiol. 2004 Apr; 286(4):F617-24.
    View in: PubMed
    Score: 0.188
  13. Wagner MC, Sandoval RM, Yadav SPS, Campos SB, Rhodes GJ, Phillips CL, Molitoris BA. Lrpap1 (RAP) Inhibits Proximal Tubule Clathrin Mediated and Clathrin Independent Endocytosis, Ameliorating Renal Aminoglycoside Nephrotoxicity. Kidney360. 2023 05 01; 4(5):591-605.
    View in: PubMed
    Score: 0.179
  14. Sandoval RM, Bacallao RL, Dunn KW, Leiser JD, Molitoris BA. Nucleotide depletion increases trafficking of gentamicin to the Golgi complex in LLC-PK1 cells. Am J Physiol Renal Physiol. 2002 Dec; 283(6):F1422-9.
    View in: PubMed
    Score: 0.173
  15. Yadav SPS, Yu A, Zhao J, Singh J, Kakkar S, Chakraborty S, Mechref Y, Molitoris B, Wagner MC. Glycosylation of a key cubilin Asn residue results in reduced binding to albumin. J Biol Chem. 2022 10; 298(10):102371.
    View in: PubMed
    Score: 0.172
  16. Herget-Rosenthal S, Hosford M, Kribben A, Atkinson SJ, Sandoval RM, Molitoris BA. Characteristics of EYFP-actin and visualization of actin dynamics during ATP depletion and repletion. Am J Physiol Cell Physiol. 2001 Dec; 281(6):C1858-70.
    View in: PubMed
    Score: 0.164
  17. Ashworth SL, Sandoval RM, Hosford M, Bamburg JR, Molitoris BA. Ischemic injury induces ADF relocalization to the apical domain of rat proximal tubule cells. Am J Physiol Renal Physiol. 2001 May; 280(5):F886-94.
    View in: PubMed
    Score: 0.158
  18. Yadav SPS, Sandoval RM, Zhao J, Huang Y, Wang E, Kumar S, Campos-Bilderback SB, Rhodes G, Mechref Y, Molitoris BA, Wagner MC. Mechanism of how carbamylation reduces albumin binding to FcRn contributing to increased vascular clearance. Am J Physiol Renal Physiol. 2021 01 01; 320(1):F114-F129.
    View in: PubMed
    Score: 0.154
  19. Liu XF, Wei J, Zhou Q, Molitoris BA, Sandoval R, Kobayashi H, Okada R, Nagaya T, Karim B, Butcher D, Pastan I. Immunotoxin SS1P is rapidly removed by proximal tubule cells of kidney, whose damage contributes to albumin loss in urine. Proc Natl Acad Sci U S A. 2020 03 17; 117(11):6086-6091.
    View in: PubMed
    Score: 0.146
  20. Uchida M, Maier B, Waghwani HK, Selivanovitch E, Pay SL, Avera J, Yun E, Sandoval RM, Molitoris BA, Zollman A, Douglas T, Hato T. The archaeal Dps nanocage targets kidney proximal tubules via glomerular filtration. J Clin Invest. 2019 09 03; 129(9):3941-3951.
    View in: PubMed
    Score: 0.141
  21. Ferrell N, Sandoval RM, Molitoris BA, Brakeman P, Roy S, Fissell WH. Application of physiological shear stress to renal tubular epithelial cells. Methods Cell Biol. 2019; 153:43-67.
    View in: PubMed
    Score: 0.138
  22. Schwartz N, Hosford M, Sandoval RM, Wagner MC, Atkinson SJ, Bamburg J, Molitoris BA. Ischemia activates actin depolymerizing factor: role in proximal tubule microvillar actin alterations. Am J Physiol. 1999 04; 276(4):F544-51.
    View in: PubMed
    Score: 0.137
  23. Endres BT, Sandoval RM, Rhodes GJ, Campos-Bilderback SB, Kamocka MM, McDermott-Roe C, Staruschenko A, Molitoris BA, Geurts AM, Palygin O. Intravital imaging of the kidney in a rat model of salt-sensitive hypertension. Am J Physiol Renal Physiol. 2017 Aug 01; 313(2):F163-F173.
    View in: PubMed
    Score: 0.119
  24. Sundin DP, Meyer C, Dahl R, Geerdes A, Sandoval R, Molitoris BA. Cellular mechanism of aminoglycoside tolerance in long-term gentamicin treatment. Am J Physiol. 1997 Apr; 272(4 Pt 1):C1309-18.
    View in: PubMed
    Score: 0.119
  25. Molitoris BA, Wagner MC. Surface membrane polarity of proximal tubular cells: alterations as a basis for malfunction. Kidney Int. 1996 Jun; 49(6):1592-7.
    View in: PubMed
    Score: 0.112
  26. Sundin DP, Cohen M, Dahl R, Falk S, Molitoris BA. Characterization of the beta 2-microglobulin endocytic pathway in rat proximal tubule cells. Am J Physiol. 1994 Sep; 267(3 Pt 2):F380-9.
    View in: PubMed
    Score: 0.099
  27. Molitoris BA. Therapeutic translation in acute kidney injury: the epithelial/endothelial axis. J Clin Invest. 2014 Jun; 124(6):2355-63.
    View in: PubMed
    Score: 0.098
  28. Ford DM, Dahl RH, Lamp CA, Molitoris BA. Apically and basolaterally internalized aminoglycosides colocalize in LLC-PK1 lysosomes and alter cell function. Am J Physiol. 1994 Jan; 266(1 Pt 1):C52-7.
    View in: PubMed
    Score: 0.095
  29. Molitoris BA, Meyer C, Dahl R, Geerdes A. Mechanism of ischemia-enhanced aminoglycoside binding and uptake by proximal tubule cells. Am J Physiol. 1993 May; 264(5 Pt 2):F907-16.
    View in: PubMed
    Score: 0.091
  30. Hall AM, Rhodes GJ, Sandoval RM, Corridon PR, Molitoris BA. In vivo multiphoton imaging of mitochondrial structure and function during acute kidney injury. Kidney Int. 2013 Jan; 83(1):72-83.
    View in: PubMed
    Score: 0.087
  31. Molitoris BA, Dahl R, Geerdes A. Cytoskeleton disruption and apical redistribution of proximal tubule Na(+)-K(+)-ATPase during ischemia. Am J Physiol. 1992 Sep; 263(3 Pt 2):F488-95.
    View in: PubMed
    Score: 0.087
  32. Saleh MA, Sandoval RM, Rhodes GJ, Campos-Bilderback SB, Molitoris BA, Pollock DM. Chronic endothelin-1 infusion elevates glomerular sieving coefficient and proximal tubular albumin reuptake in the rat. Life Sci. 2012 Oct 15; 91(13-14):634-7.
    View in: PubMed
    Score: 0.085
  33. Canfield PE, Geerdes AM, Molitoris BA. Effect of reversible ATP depletion on tight-junction integrity in LLC-PK1 cells. Am J Physiol. 1991 Dec; 261(6 Pt 2):F1038-45.
    View in: PubMed
    Score: 0.082
  34. Spiegel DM, Shanley PF, Molitoris BA. Mild ischemia predisposes the S3 segment to gentamicin toxicity. Kidney Int. 1990 Sep; 38(3):459-64.
    View in: PubMed
    Score: 0.075
  35. Molitoris BA, Falk SA, Dahl RH. Ischemia-induced loss of epithelial polarity. Role of the tight junction. J Clin Invest. 1989 Oct; 84(4):1334-9.
    View in: PubMed
    Score: 0.071
  36. Spiegel DM, Wilson PD, Molitoris BA. Epithelial polarity following ischemia: a requirement for normal cell function. Am J Physiol. 1989 Mar; 256(3 Pt 2):F430-6.
    View in: PubMed
    Score: 0.068
  37. Russo LM, Sandoval RM, Campos SB, Molitoris BA, Comper WD, Brown D. Impaired tubular uptake explains albuminuria in early diabetic nephropathy. J Am Soc Nephrol. 2009 Mar; 20(3):489-94.
    View in: PubMed
    Score: 0.067
  38. Russo LM, Sandoval RM, McKee M, Osicka TM, Collins AB, Brown D, Molitoris BA, Comper WD. The normal kidney filters nephrotic levels of albumin retrieved by proximal tubule cells: retrieval is disrupted in nephrotic states. Kidney Int. 2007 Mar; 71(6):504-13.
    View in: PubMed
    Score: 0.059
  39. Molitoris BA, Hoilien C. Static and dynamic components of renal cortical brush border and basolateral membrane fluidity: role of cholesterol. J Membr Biol. 1987; 99(3):165-72.
    View in: PubMed
    Score: 0.058
  40. Molitoris BA, Sandoval RM. Quantifying dynamic kidney processes utilizing multi-photon microscopy. Contrib Nephrol. 2007; 156:227-35.
    View in: PubMed
    Score: 0.058
  41. Molitoris BA, Wilson PD, Schrier RW, Simon FR. Ischemia induces partial loss of surface membrane polarity and accumulation of putative calcium ionophores. J Clin Invest. 1985 Dec; 76(6):2097-105.
    View in: PubMed
    Score: 0.054
  42. Molitoris BA. Actin cytoskeleton in ischemic acute renal failure. Kidney Int. 2004 Aug; 66(2):871-83.
    View in: PubMed
    Score: 0.049
  43. Bryniarski MA, Sandoval RM, Ruszaj DM, Fraser-McArthur J, Yee BM, Yacoub R, Chaves LD, Campos-Bilderback SB, Molitoris BA, Morris ME. Defining the Intravital Renal Disposition of Fluorescence-Quenched Exenatide. Mol Pharm. 2023 02 06; 20(2):987-996.
    View in: PubMed
    Score: 0.044
  44. Dunn KW, Sandoval RM, Kelly KJ, Dagher PC, Tanner GA, Atkinson SJ, Bacallao RL, Molitoris BA. Functional studies of the kidney of living animals using multicolor two-photon microscopy. Am J Physiol Cell Physiol. 2002 Sep; 283(3):C905-16.
    View in: PubMed
    Score: 0.043
  45. Kolb AL, Corridon PR, Zhang S, Xu W, Witzmann FA, Collett JA, Rhodes GJ, Winfree S, Bready D, Pfeffenberger ZJ, Pomerantz JM, Hato T, Nagami GT, Molitoris BA, Basile DP, Atkinson SJ, Bacallao RL. Exogenous Gene Transmission of Isocitrate Dehydrogenase 2 Mimics Ischemic Preconditioning Protection. J Am Soc Nephrol. 2018 04; 29(4):1154-1164.
    View in: PubMed
    Score: 0.031
  46. Wagner MC, Molitoris BA. ATP depletion alters myosin I beta cellular location in LLC-PK1 cells. Am J Physiol. 1997 May; 272(5 Pt 1):C1680-90.
    View in: PubMed
    Score: 0.030
  47. Leiser J, Molitoris BA. Disease processes in epithelia: the role of the actin cytoskeleton and altered surface membrane polarity. Biochim Biophys Acta. 1993 Nov 25; 1225(1):1-13.
    View in: PubMed
    Score: 0.024
  48. Molitoris BA. New insights into the cell biology of ischemic acute renal failure. J Am Soc Nephrol. 1991 Jun; 1(12):1263-70.
    View in: PubMed
    Score: 0.020
  49. Molitoris BA, Chan LK, Shapiro JI, Conger JD, Falk SA. Loss of epithelial polarity: a novel hypothesis for reduced proximal tubule Na+ transport following ischemic injury. J Membr Biol. 1989 Feb; 107(2):119-27.
    View in: PubMed
    Score: 0.017
  50. Hörbelt M, Wotzlaw C, Sutton TA, Molitoris BA, Philipp T, Kribben A, Fandrey J, Pietruck F. Organic cation transport in the rat kidney in vivo visualized by time-resolved two-photon microscopy. Kidney Int. 2007 Aug; 72(4):422-9.
    View in: PubMed
    Score: 0.015
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

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