Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Last Name
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Katrina G. Claw

TitleAssociate Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-BIOMED Informatics Gen Ops

    Collapse Research 
    Collapse research activities and funding
    R13HG014112     (CLAW, KATRINA G)Dec 16, 2024 - Nov 30, 2025
    NIH
    Informing the Navajo Public about Genetic Research and Policy
    Role: Principal Investigator
    DP1DA061279     (CLAW, KATRINA G)Aug 15, 2024 - May 31, 2029
    NIH
    Precision pharmacogenomics and Indigenous research: A novel approach to tobacco cessation efficacy in American Indian communities
    Role: Principal Investigator
    R35HG011319     (CLAW, KATRINA G)Sep 1, 2020 - Jun 30, 2025
    NIH
    Pharmacogenomic approaches to drug metabolism in American Indian/Alaska Native People
    Role: Principal Investigator
    F32GM119237     (CLAW, KATRINA G)Jun 1, 2016 - May 31, 2019
    NIH
    Variation of vitamin D metabolism and regulatory genes in the Yup?ik population
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Halmai NB, Taitingfong R, Jennings LL, Yracheta J, Garba I, Lund JR, Curley CA, Claw KG, Taualii M, Garrison NA, Carroll SR. Indigenous Data Sovereignty in Genomics and Human Genetics: Genomic Equity and Justice for Indigenous Peoples. Annu Rev Genomics Hum Genet. 2025 Apr 18. PMID: 40249967.
      View in: PubMed
    2. Wichman ML, Wall DM, Garcia Mota SS, Killam SR, Brown KE, Aagaard K, Swaney J, Muzquiz LI, Corum BN, Claw KG, Woodahl EL. Perspectives on Using Pharmacogenomics to Guide Tobacco Cessation: Survey Results From an American Indian Community. Clin Transl Sci. 2025 Mar; 18(3):e70194. PMID: 40078094.
      View in: PubMed
    3. Sherman CA, Claw KG, Lee SB. Pharmacogenetic analysis of structural variation in the 1000 genomes project using whole genome sequences. Sci Rep. 2024 10 01; 14(1):22774. PMID: 39354004.
      View in: PubMed
    4. Russell LE, Claw KG, Aagaard KM, Glass SM, Dasgupta K, Nez FL, Haimbaugh A, Maldonato BJ, Yadav J. Insights into pharmacogenetics, drug-gene interactions, and drug-drug-gene interactions. Drug Metab Rev. 2024 Aug 18; 1-19. PMID: 39154360.
      View in: PubMed
    5. Barton KS, Porter KM, Mai T, Claw KG, Hiratsuka VY, Carroll SR, Burke W, Garrison NA. Genetic research within Indigenous communities: Engagement opportunities and pathways forward. Genet Med. 2024 Jul; 26(7):101158. PMID: 38699966.
      View in: PubMed
    6. Alade AN, Claw KG, McDonald MG, Prasad B, Rettie AE, Thummel KE. Cytochrome P450 Family 4F2 and 4F11 Haplotype Mapping and Association with Hepatic Gene Expression and Vitamin K Hydroxylation Activity. ACS Pharmacol Transl Sci. 2024 Mar 08; 7(3):716-732. PMID: 38481683.
      View in: PubMed
    7. Claw KG, Dorr CR, Woodahl EL. Implementing community-engaged pharmacogenomics in Indigenous communities. Nat Commun. 2024 Jan 31; 15(1):920. PMID: 38296967.
      View in: PubMed
    8. Avey JP, Schaefer KR, Noonan CJ, Trinidad SB, Muller CJ, Claw KG, Dillard DA, Todd MR, Beans JA, Tyndale RF, Robinson RF, Thummel KE. Identification of Sociodemographic, Clinical, and Genetic Factors to Aid Alaska Native and American Indian People to Successfully Quit Smoking. Nicotine Tob Res. 2024 01 01; 26(1):79-86. PMID: 37527452.
      View in: PubMed
    9. Wroblewski TH, Witt KE, Lee SB, Malhi RS, Peede D, Huerta-S?nchez E, Villanea FA, Claw KG. Pharmacogenetic Variation in Neanderthals and Denisovans and Implications for Human Health and Response to Medications. Genome Biol Evol. 2023 12 01; 15(12). PMID: 38051947.
      View in: PubMed
    10. Claw KG, Nashoba A. Indigenous diversity in Australia's DNA tapestry unlocked for genetic equity. Nature. 2023 Dec; 624(7992):536-537. PMID: 38093045.
      View in: PubMed
    11. Maldonado BL, Piqu? DG, Kaplan RC, Claw KG, Gignoux CR. Genetic risk prediction in Hispanics/Latinos: milestones, challenges, and social-ethical considerations. J Community Genet. 2023 Dec; 14(6):543-553. PMID: 37962783.
      View in: PubMed
    12. Lasisi T, Claw KG, Fox K, Zaidi AA. Editorial: The ethics and challenges of studying the genetics of marginalized populations. Front Genet. 2023; 14:1260457. PMID: 37674477.
      View in: PubMed
    13. Fleskes RE, Bader AC, Tsosie KS, Wagner JK, Claw KG, Garrison NA. Ethical Guidance in Human Paleogenomics: New and Ongoing Perspectives. Annu Rev Genomics Hum Genet. 2022 08 31; 23:627-652. PMID: 35537469.
      View in: PubMed
    14. Claw KG, Dundas N, Parrish MS, Begay RL, Teller TL, Garrison NA, Sage F. Perspectives on Genetic Research: Results From a Survey of Navajo Community Members. Front Genet. 2021; 12:734529. PMID: 34925442.
      View in: PubMed
    15. Tsosie KS, Claw KG, Garrison NA. Considering "Respect for Sovereignty" Beyond the Belmont Report and the Common Rule: Ethical and Legal Implications for American Indian and Alaska Native Peoples. Am J Bioeth. 2021 Oct; 21(10):27-30. PMID: 34554064.
      View in: PubMed
    16. El-Boraie A, Tanner JA, Zhu AZX, Claw KG, Prasad B, Schuetz EG, Thummel KE, Fukunaga K, Mushiroda T, Kubo M, Benowitz NL, Lerman C, Tyndale RF. Functional characterization of novel rare CYP2A6 variants and potential implications for clinical outcomes. Clin Transl Sci. 2022 01; 15(1):204-220. PMID: 34476898.
      View in: PubMed
    17. Schaefer KR, Avey JP, Todd MR, Beans JA, Dillard DA, Shireman LM, Thornton TA, Tyndale RF, Thummel KE, Robinson RF, Claw KG. Nicotine metabolism and its association with CYP2A6 genotype among Indigenous people in Alaska who smoke. Clin Transl Sci. 2021 11; 14(6):2474-2486. PMID: 34520119.
      View in: PubMed
    18. Fohner AE, Dalton R, Skagen K, Jackson K, Claw KG, Hopkins SE, Robinson R, Khan BA, Prasad B, Schuetz EG, Nickerson DA, Thornton TA, Dillard DA, Boyer BB, Thummel KE, Woodahl EL. Characterization of CYP3A pharmacogenetic variation in American Indian and Alaska Native communities, targeting CYP3A4*1G allele function. Clin Transl Sci. 2021 Jul; 14(4):1292-1302. PMID: 33503331.
      View in: PubMed
    19. Hiratsuka VY, Hahn MJ, Woodbury RB, Hull SC, Wilson DR, Bonham VL, Dillard DA, Avey JP, Beckel-Mitchener AC, Blome J, Claw K, Ferucci ED, Gachupin FC, Ghazarian A, Hindorff L, Jooma S, Trinidad SB, Troyer J, Walajahi H. Alaska Native genomic research: perspectives from Alaska Native leaders, federal staff, and biomedical researchers. Genet Med. 2020 Dec; 22(12):1935-1943. PMID: 32839571.
      View in: PubMed
    20. Wagner JK, Colwell C, Claw KG, Stone AC, Bolnick DA, Hawks J, Brothers KB, Garrison NA. Fostering Responsible Research on Ancient DNA. Am J Hum Genet. 2020 08 06; 107(2):183-195. PMID: 32763189.
      View in: PubMed
    21. Tsosie KS, Claw KG. Indigenizing Science and Reasserting Indigeneity in Research. Hum Biol. 2020 07 09; 91(3):137-140. PMID: 32549033.
      View in: PubMed
    22. Begay RL, Garrison NA, Sage F, Bauer M, Knoki-Wilson U, Begay DH, Becenti-Pigman B, Claw KG. Weaving the Strands of Life (Iin? Bitl'ool): History of Genetic Research Involving Navajo People. Hum Biol. 2020 07 09; 91(3):189-208. PMID: 32549035.
      View in: PubMed
    23. Claw KG, Beans JA, Lee SB, Avey JP, Stapleton PA, Scherer SE, El-Boraie A, Tyndale RF, Nickerson DA, Dillard DA, Thummel KE, Robinson RF. Pharmacogenomics of Nicotine Metabolism: Novel CYP2A6 and CYP2B6 Genetic Variation Patterns in Alaska Native and American Indian Populations. Nicotine Tob Res. 2020 May 26; 22(6):910-918. PMID: 31241144.
      View in: PubMed
    24. Dalton R, Lee SB, Claw KG, Prasad B, Phillips BR, Shen DD, Wong LH, Fade M, McDonald MG, Dunham MJ, Fowler DM, Rettie AE, Schuetz E, Thornton TA, Nickerson DA, Gaedigk A, Thummel KE, Woodahl EL. Interrogation of CYP2D6 Structural Variant Alleles Improves the Correlation Between CYP2D6 Genotype and CYP2D6-Mediated Metabolic Activity. Clin Transl Sci. 2020 01; 13(1):147-156. PMID: 31536170.
      View in: PubMed
    25. James RD, West KM, Claw KG, EchoHawk A, Dodge L, Dominguez A, Taualii M, Forquera R, Thummel K, Burke W. Responsible Research With Urban American Indians and Alaska Natives. Am J Public Health. 2018 Dec; 108(12):1613-1616. PMID: 30359103.
      View in: PubMed
    26. Claw KG, Anderson MZ, Begay RL, Tsosie KS, Fox K, Garrison NA. A framework for enhancing ethical genomic research with Indigenous communities. Nat Commun. 2018 07 27; 9(1):2957. PMID: 30054469.
      View in: PubMed
    27. Claw KG, George RD, MacCoss MJ, Swanson WJ. Quantitative evolutionary proteomics of seminal fluid from primates with different mating systems. BMC Genomics. 2018 Jun 22; 19(1):488. PMID: 29929489.
      View in: PubMed
    28. Bhatt DK, Basit A, Zhang H, Gaedigk A, Lee SB, Claw KG, Mehrotra A, Chaudhry AS, Pearce RE, Gaedigk R, Broeckel U, Thornton TA, Nickerson DA, Schuetz EG, Amory JK, Leeder JS, Prasad B. Hepatic Abundance and Activity of Androgen- and Drug-Metabolizing Enzyme UGT2B17 Are Associated with Genotype, Age, and Sex. Drug Metab Dispos. 2018 06; 46(6):888-896. PMID: 29602798.
      View in: PubMed
    29. Henderson LM, Claw KG, Woodahl EL, Robinson RF, Boyer BB, Burke W, Thummel KE. P450 Pharmacogenetics in Indigenous North American Populations. J Pers Med. 2018 Feb 01; 8(1). PMID: 29389890.
      View in: PubMed
    30. Wong T, Wang Z, Chapron BD, Suzuki M, Claw KG, Gao C, Foti RS, Prasad B, Chapron A, Calamia J, Chaudhry A, Schuetz EG, Horst RL, Mao Q, de Boer IH, Thornton TA, Thummel KE. Polymorphic Human Sulfotransferase 2A1 Mediates the Formation of 25-Hydroxyvitamin D3-3-O-Sulfate, a Major Circulating Vitamin D Metabolite in Humans. Drug Metab Dispos. 2018 04; 46(4):367-379. PMID: 29343609.
      View in: PubMed
    31. Tanner JA, Zhu AZ, Claw KG, Prasad B, Korchina V, Hu J, Doddapaneni H, Muzny DM, Schuetz EG, Lerman C, Thummel KE, Scherer SE, Tyndale RF. Novel CYP2A6 diplotypes identified through next-generation sequencing are associated with in-vitro and in-vivo nicotine metabolism. Pharmacogenet Genomics. 2018 Jan; 28(1):7-16. PMID: 29232328.
      View in: PubMed
    32. Xu M, Bhatt DK, Yeung CK, Claw KG, Chaudhry AS, Gaedigk A, Pearce RE, Broeckel U, Gaedigk R, Nickerson DA, Schuetz E, Rettie AE, Leeder JS, Thummel KE, Prasad B. Genetic and Nongenetic Factors Associated with Protein Abundance of Flavin-Containing Monooxygenase 3 in Human Liver. J Pharmacol Exp Ther. 2017 11; 363(2):265-274. PMID: 28819071.
      View in: PubMed
    33. Claw KG, Lippert D, Bardill J, Cordova A, Fox K, Yracheta JM, Bader AC, Bolnick DA, Malhi RS, TallBear K, Garrison NA. Chaco Canyon Dig Unearths Ethical Concerns. Hum Biol. 2017 07; 89(3):177-180. PMID: 29745246.
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    34. Tanner JA, Prasad B, Claw KG, Stapleton P, Chaudhry A, Schuetz EG, Thummel KE, Tyndale RF. Predictors of Variation in CYP2A6 mRNA, Protein, and Enzyme Activity in a Human Liver Bank: Influence of Genetic and Nongenetic Factors. J Pharmacol Exp Ther. 2017 Jan; 360(1):129-139. PMID: 27815364.
      View in: PubMed
    35. Chen LL, Claw KG, Ramachandran S. A two-fold challenge: the experience of women of color in genomics. Genome Biol. 2016 10 11; 17(1):210. PMID: 27729075.
      View in: PubMed
    36. Claw KG, George RD, Swanson WJ. Detecting coevolution in mammalian sperm-egg fusion proteins. Mol Reprod Dev. 2014 Jun; 81(6):531-8. PMID: 24644026.
      View in: PubMed
    37. Claw KG, Swanson WJ. Evolution of the egg: new findings and challenges. Annu Rev Genomics Hum Genet. 2012; 13:109-25. PMID: 22703177.
      View in: PubMed
    38. Claw KG, Tito RY, Stone AC, Verrelli BC. Haplotype structure and divergence at human and chimpanzee serotonin transporter and receptor genes: implications for behavioral disorder association analyses. Mol Biol Evol. 2010 Jul; 27(7):1518-29. PMID: 20118193.
      View in: PubMed
    39. Perry GH, Dominy NJ, Claw KG, Lee AS, Fiegler H, Redon R, Werner J, Villanea FA, Mountain JL, Misra R, Carter NP, Lee C, Stone AC. Diet and the evolution of human amylase gene copy number variation. Nat Genet. 2007 Oct; 39(10):1256-60. PMID: 17828263.
      View in: PubMed
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