 Connection
Marc Goalstone to Insulin
This is a "connection" page, showing publications Marc Goalstone has written about Insulin.
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Connection Strength |
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1.600 |
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Mackesy DZ, Goalstone ML. Extracellular signal-regulated kinase-5: Novel mediator of insulin and tumor necrosis factor a-stimulated vascular cell adhesion molecule-1 expression in vascular cells. J Diabetes. 2014 Nov; 6(6):595-602.
Score: 0.198
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Sharma G, Goalstone ML. Regulation of ERK5 by insulin and angiotensin-II in vascular smooth muscle cells. Biochem Biophys Res Commun. 2007 Mar 23; 354(4):1078-83.
Score: 0.121
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Solomon CS, Leitner JW, Goalstone ML. Dominant negative alpha-subunit of farnesyl- and geranylgeranyl-transferase I inhibits insulin-induced differentiation of 3T3-L1 pre-adipocytes. Int J Obes Relat Metab Disord. 2003 Jan; 27(1):40-7.
Score: 0.091
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Solomon CS, Goalstone ML. Dominant negative alpha-subunit of FTase inhibits effects of insulin and IGF-I in MCF-7 cells. Biochem Biophys Res Commun. 2002 Mar 01; 291(3):458-65.
Score: 0.086
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Solomon CS, Goalstone ML. Dominant negative farnesyltransferase alpha-subunit inhibits insulin mitogenic effects. Biochem Biophys Res Commun. 2001 Jul 13; 285(2):161-6.
Score: 0.082
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Goalstone ML, Leitner JW, Berhanu P, Sharma PM, Olefsky JM, Draznin B. Insulin signals to prenyltransferases via the Shc branch of intracellular signaling. J Biol Chem. 2001 Apr 20; 276(16):12805-12.
Score: 0.080
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Draznin B, Miles P, Kruszynska Y, Olefsky J, Friedman J, Golovchenko I, Stjernholm R, Wall K, Reitman M, Accili D, Cooksey R, McClain D, Goalstone M. Effects of insulin on prenylation as a mechanism of potentially detrimental influence of hyperinsulinemia. Endocrinology. 2000 Apr; 141(4):1310-6.
Score: 0.075
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Goalstone ML, Leitner JW, Golovchenko I, Stjernholm MR, Cormont M, Le Marchand-Brustel Y, Draznin B. Insulin promotes phosphorylation and activation of geranylgeranyltransferase II. Studies with geranylgeranylation of rab-3 and rab-4. J Biol Chem. 1999 Jan 29; 274(5):2880-4.
Score: 0.069
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Goalstone ML, Draznin B. Effect of insulin on farnesyltransferase gene transcription and mRNA stability. Biochem Biophys Res Commun. 1999 Jan 08; 254(1):243-7.
Score: 0.069
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Goalstone ML, Natarajan R, Standley PR, Walsh MF, Leitner JW, Carel K, Scott S, Nadler J, Sowers JR, Draznin B. Insulin potentiates platelet-derived growth factor action in vascular smooth muscle cells. Endocrinology. 1998 Oct; 139(10):4067-72.
Score: 0.068
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Goalstone ML, Leitner JW, Wall K, Dolgonos L, Rother KI, Accili D, Draznin B. Effect of insulin on farnesyltransferase. Specificity of insulin action and potentiation of nuclear effects of insulin-like growth factor-1, epidermal growth factor, and platelet-derived growth factor. J Biol Chem. 1998 Sep 11; 273(37):23892-6.
Score: 0.068
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Goalstone ML, Draznin B. What does insulin do to Ras? Cell Signal. 1998 May; 10(5):297-301.
Score: 0.066
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Goalstone M, Carel K, Leitner JW, Draznin B. Insulin stimulates the phosphorylation and activity of farnesyltransferase via the Ras-mitogen-activated protein kinase pathway. Endocrinology. 1997 Dec; 138(12):5119-24.
Score: 0.064
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Goalstone M, Leitner JW, Draznin B. GTP loading of farnesylated p21Ras by insulin at the plasma membrane. Biochem Biophys Res Commun. 1997 Oct 09; 239(1):42-5.
Score: 0.063
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Goalstone ML, Draznin B. Insulin signaling. West J Med. 1997 Sep; 167(3):166-73.
Score: 0.063
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Goalstone ML, Draznin B. Effect of insulin on farnesyltransferase activity in 3T3-L1 adipocytes. J Biol Chem. 1996 Nov 01; 271(44):27585-9.
Score: 0.059
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Goalstone ML. ERK5: a novel IKKa-kinase in rat hippocampal neurons. Can J Neurol Sci. 2011 Jul; 38(4):639-48.
Score: 0.041
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Sharma G, Goalstone ML. Dominant negative FTase (DNFTalpha) inhibits ERK5, MEF2C and CREB activation in adipogenesis. Mol Cell Endocrinol. 2005 Dec 21; 245(1-2):93-104.
Score: 0.028
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Finlayson CA, Chappell J, Leitner JW, Goalstone ML, Garrity M, Nawaz S, Ciaraldi TP, Draznin B. Enhanced insulin signaling via Shc in human breast cancer. Metabolism. 2003 Dec; 52(12):1606-11.
Score: 0.024
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Golovchenko I, Yang CH, Goalstone ML, Draznin B. Garlic extract methylallyl thiosulfinate blocks insulin potentiation of platelet-derived growth factor-stimulated migration of vascular smooth muscle cells. Metabolism. 2003 Feb; 52(2):254-9.
Score: 0.023
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Montagnani M, Golovchenko I, Kim I, Koh GY, Goalstone ML, Mundhekar AN, Johansen M, Kucik DF, Quon MJ, Draznin B. Inhibition of phosphatidylinositol 3-kinase enhances mitogenic actions of insulin in endothelial cells. J Biol Chem. 2002 Jan 18; 277(3):1794-9.
Score: 0.021
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Chappell J, Leitner JW, Solomon S, Golovchenko I, Goalstone ML, Draznin B. Effect of insulin on cell cycle progression in MCF-7 breast cancer cells. Direct and potentiating influence. J Biol Chem. 2001 Oct 12; 276(41):38023-8.
Score: 0.021
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Klemm DJ, Leitner JW, Watson P, Nesterova A, Reusch JE, Goalstone ML, Draznin B. Insulin-induced adipocyte differentiation. Activation of CREB rescues adipogenesis from the arrest caused by inhibition of prenylation. J Biol Chem. 2001 Jul 27; 276(30):28430-5.
Score: 0.020
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Chappell J, Golovchenko I, Wall K, Stjernholm R, Leitner JW, Goalstone M, Draznin B. Potentiation of Rho-A-mediated lysophosphatidic acid activity by hyperinsulinemia. J Biol Chem. 2000 Oct 13; 275(41):31792-7.
Score: 0.020
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Goalstone ML, Wall K, Leitner JW, Kurowski T, Ruderman N, Pan SJ, Ivy JL, Moller DE, Draznin B. Increased amounts of farnesylated p21Ras in tissues of hyperinsulinaemic animals. Diabetologia. 1999 Mar; 42(3):310-6.
Score: 0.017
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Leitner JW, Kline T, Carel K, Goalstone M, Draznin B. Hyperinsulinemia potentiates activation of p21Ras by growth factors. Endocrinology. 1997 May; 138(5):2211-4.
Score: 0.015
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Veluthakal R, Arora DK, Goalstone ML, Kowluru RA, Kowluru A. Metabolic Stress Induces Caspase-3 Mediated Degradation and Inactivation of Farnesyl and Geranylgeranyl Transferase Activities in Pancreatic ß-Cells. Cell Physiol Biochem. 2016; 39(6):2110-2120.
Score: 0.015
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Stith BJ, Goalstone ML, Espinoza R, Mossel C, Roberts D, Wiernsperger N. The antidiabetic drug metformin elevates receptor tyrosine kinase activity and inositol 1,4,5-trisphosphate mass in Xenopus oocytes. Endocrinology. 1996 Jul; 137(7):2990-9.
Score: 0.015
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Cornier MA, Donahoo WT, Pereira R, Gurevich I, Westergren R, Enerback S, Eckel PJ, Goalstone ML, Hill JO, Eckel RH, Draznin B. Insulin sensitivity determines the effectiveness of dietary macronutrient composition on weight loss in obese women. Obes Res. 2005 Apr; 13(4):703-9.
Score: 0.007
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Stephens E, Thureen PJ, Goalstone ML, Anderson MS, Leitner JW, Hay WW, Draznin B. Fetal hyperinsulinemia increases farnesylation of p21 Ras in fetal tissues. Am J Physiol Endocrinol Metab. 2001 Aug; 281(2):E217-23.
Score: 0.005
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Golovchenko I, Goalstone ML, Watson P, Brownlee M, Draznin B. Hyperinsulinemia enhances transcriptional activity of nuclear factor-kappaB induced by angiotensin II, hyperglycemia, and advanced glycosylation end products in vascular smooth muscle cells. Circ Res. 2000 Oct 27; 87(9):746-52.
Score: 0.005
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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