Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution

Connection

Thomas Cech to DNA-Binding Proteins

This is a "connection" page, showing publications Thomas Cech has written about DNA-Binding Proteins.

 
Connection Strength
 
 
 
3.951
 
  1. Hemphill WO, Voong CK, Fenske R, Goodrich JA, Cech TR. Multiple RNA- and DNA-binding proteins exhibit direct transfer of polynucleotides with implications for target-site search. Proc Natl Acad Sci U S A. 2023 06 27; 120(26):e2220537120.
    View in: PubMed
    Score: 0.534
  2. Wang X, Paucek RD, Gooding AR, Brown ZZ, Ge EJ, Muir TW, Cech TR. Molecular analysis of PRC2 recruitment to DNA in chromatin and its inhibition by RNA. Nat Struct Mol Biol. 2017 Dec; 24(12):1028-1038.
    View in: PubMed
    Score: 0.361
  3. Dalby AB, Goodrich KJ, Pfingsten JS, Cech TR. RNA recognition by the DNA end-binding Ku heterodimer. RNA. 2013 Jun; 19(6):841-51.
    View in: PubMed
    Score: 0.264
  4. Pfingsten JS, Goodrich KJ, Taabazuing C, Ouenzar F, Chartrand P, Cech TR. Mutually exclusive binding of telomerase RNA and DNA by Ku alters telomerase recruitment model. Cell. 2012 Mar 02; 148(5):922-32.
    View in: PubMed
    Score: 0.244
  5. Zappulla DC, Goodrich KJ, Arthur JR, Gurski LA, Denham EM, Stellwagen AE, Cech TR. Ku can contribute to telomere lengthening in yeast at multiple positions in the telomerase RNP. RNA. 2011 Feb; 17(2):298-311.
    View in: PubMed
    Score: 0.225
  6. Nandakumar J, Podell ER, Cech TR. How telomeric protein POT1 avoids RNA to achieve specificity for single-stranded DNA. Proc Natl Acad Sci U S A. 2010 Jan 12; 107(2):651-6.
    View in: PubMed
    Score: 0.210
  7. Jacobs SA, Podell ER, Cech TR. Crystal structure of the essential N-terminal domain of telomerase reverse transcriptase. Nat Struct Mol Biol. 2006 Mar; 13(3):218-25.
    View in: PubMed
    Score: 0.160
  8. Jacobs SA, Podell ER, Wuttke DS, Cech TR. Soluble domains of telomerase reverse transcriptase identified by high-throughput screening. Protein Sci. 2005 Aug; 14(8):2051-8.
    View in: PubMed
    Score: 0.155
  9. Zaug AJ, Podell ER, Cech TR. Human POT1 disrupts telomeric G-quadruplexes allowing telomerase extension in vitro. Proc Natl Acad Sci U S A. 2005 Aug 02; 102(31):10864-9.
    View in: PubMed
    Score: 0.154
  10. Baumann P, Cech TR. Pot1, the putative telomere end-binding protein in fission yeast and humans. Science. 2001 May 11; 292(5519):1171-5.
    View in: PubMed
    Score: 0.115
  11. Baumann P, Cech TR. Protection of telomeres by the Ku protein in fission yeast. Mol Biol Cell. 2000 Oct; 11(10):3265-75.
    View in: PubMed
    Score: 0.111
  12. Froelich-Ammon SJ, Dickinson BA, Bevilacqua JM, Schultz SC, Cech TR. Modulation of telomerase activity by telomere DNA-binding proteins in Oxytricha. Genes Dev. 1998 May 15; 12(10):1504-14.
    View in: PubMed
    Score: 0.094
  13. Long Y, Wang X, Youmans DT, Cech TR. How do lncRNAs regulate transcription? Sci Adv. 2017 09; 3(9):eaao2110.
    View in: PubMed
    Score: 0.090
  14. Cooper JP, Nimmo ER, Allshire RC, Cech TR. Regulation of telomere length and function by a Myb-domain protein in fission yeast. Nature. 1997 Feb 20; 385(6618):744-7.
    View in: PubMed
    Score: 0.086
  15. Hicke BJ, Willis MC, Koch TH, Cech TR. Telomeric protein-DNA point contacts identified by photo-cross-linking using 5-bromodeoxyuridine. Biochemistry. 1994 Mar 22; 33(11):3364-73.
    View in: PubMed
    Score: 0.070
  16. Fang G, Cech TR. Characterization of a G-quartet formation reaction promoted by the beta-subunit of the Oxytricha telomere-binding protein. Biochemistry. 1993 Nov 02; 32(43):11646-57.
    View in: PubMed
    Score: 0.068
  17. Fang G, Cech TR. The beta subunit of Oxytricha telomere-binding protein promotes G-quartet formation by telomeric DNA. Cell. 1993 Sep 10; 74(5):875-85.
    View in: PubMed
    Score: 0.068
  18. Ishikawa F, Matunis MJ, Dreyfuss G, Cech TR. Nuclear proteins that bind the pre-mRNA 3' splice site sequence r(UUAG/G) and the human telomeric DNA sequence d(TTAGGG)n. Mol Cell Biol. 1993 Jul; 13(7):4301-10.
    View in: PubMed
    Score: 0.067
  19. Fang G, Cech TR. Oxytricha telomere-binding protein: DNA-dependent dimerization of the alpha and beta subunits. Proc Natl Acad Sci U S A. 1993 Jul 01; 90(13):6056-60.
    View in: PubMed
    Score: 0.067
  20. Fang G, Gray JT, Cech TR. Oxytricha telomere-binding protein: separable DNA-binding and dimerization domains of the alpha-subunit. Genes Dev. 1993 May; 7(5):870-82.
    View in: PubMed
    Score: 0.066
  21. Gray JT, Celander DW, Price CM, Cech TR. Cloning and expression of genes for the Oxytricha telomere-binding protein: specific subunit interactions in the telomeric complex. Cell. 1991 Nov 15; 67(4):807-14.
    View in: PubMed
    Score: 0.060
  22. Fang GW, Cech TR. Molecular cloning of telomere-binding protein genes from Stylonychia mytilis. Nucleic Acids Res. 1991 Oct 25; 19(20):5515-8.
    View in: PubMed
    Score: 0.060
  23. Nandakumar J, Cech TR. DNA-induced dimerization of the single-stranded DNA binding telomeric protein Pot1 from Schizosaccharomyces pombe. Nucleic Acids Res. 2012 Jan; 40(1):235-44.
    View in: PubMed
    Score: 0.059
  24. Raghuraman MK, Cech TR. Effect of monovalent cation-induced telomeric DNA structure on the binding of Oxytricha telomeric protein. Nucleic Acids Res. 1990 Aug 11; 18(15):4543-52.
    View in: PubMed
    Score: 0.055
  25. Hicke BJ, Celander DW, MacDonald GH, Price CM, Cech TR. Two versions of the gene encoding the 41-kilodalton subunit of the telomere binding protein of Oxytricha nova. Proc Natl Acad Sci U S A. 1990 Feb; 87(4):1481-5.
    View in: PubMed
    Score: 0.053
  26. Latrick CM, Cech TR. POT1-TPP1 enhances telomerase processivity by slowing primer dissociation and aiding translocation. EMBO J. 2010 Mar 03; 29(5):924-33.
    View in: PubMed
    Score: 0.053
  27. Raghuraman MK, Dunn CJ, Hicke BJ, Cech TR. Oxytricha telomeric nucleoprotein complexes reconstituted with synthetic DNA. Nucleic Acids Res. 1989 Jun 12; 17(11):4235-53.
    View in: PubMed
    Score: 0.051
  28. Price CM, Cech TR. Properties of the telomeric DNA-binding protein from Oxytricha nova. Biochemistry. 1989 Jan 24; 28(2):769-74.
    View in: PubMed
    Score: 0.049
  29. Mandell JG, B?hler J, Volpe TA, Martienssen RA, Cech TR. Global expression changes resulting from loss of telomeric DNA in fission yeast. Genome Biol. 2005; 6(1):R1.
    View in: PubMed
    Score: 0.037
  30. Cech TR. Beginning to understand the end of the chromosome. Cell. 2004 Jan 23; 116(2):273-9.
    View in: PubMed
    Score: 0.035
  31. Bryan TM, Goodrich KJ, Cech TR. Tetrahymena telomerase is active as a monomer. Mol Biol Cell. 2003 Dec; 14(12):4794-804.
    View in: PubMed
    Score: 0.034
  32. Friedman KL, Heit JJ, Long DM, Cech TR. N-terminal domain of yeast telomerase reverse transcriptase: recruitment of Est3p to the telomerase complex. Mol Biol Cell. 2003 Jan; 14(1):1-13.
    View in: PubMed
    Score: 0.032
  33. Livengood AJ, Zaug AJ, Cech TR. Essential regions of Saccharomyces cerevisiae telomerase RNA: separate elements for Est1p and Est2p interaction. Mol Cell Biol. 2002 Apr; 22(7):2366-74.
    View in: PubMed
    Score: 0.031
  34. Friedman KL, Cech TR. Essential functions of amino-terminal domains in the yeast telomerase catalytic subunit revealed by selection for viable mutants. Genes Dev. 1999 Nov 01; 13(21):2863-74.
    View in: PubMed
    Score: 0.026
  35. Nakamura TM, Cooper JP, Cech TR. Two modes of survival of fission yeast without telomerase. Science. 1998 Oct 16; 282(5388):493-6.
    View in: PubMed
    Score: 0.024
  36. Lingner J, Cech TR. Telomerase and chromosome end maintenance. Curr Opin Genet Dev. 1998 Apr; 8(2):226-32.
    View in: PubMed
    Score: 0.023
  37. Nakamura TM, Morin GB, Chapman KB, Weinrich SL, Andrews WH, Lingner J, Harley CB, Cech TR. Telomerase catalytic subunit homologs from fission yeast and human. Science. 1997 Aug 15; 277(5328):955-9.
    View in: PubMed
    Score: 0.022
  38. Lingner J, Hughes TR, Shevchenko A, Mann M, Lundblad V, Cech TR. Reverse transcriptase motifs in the catalytic subunit of telomerase. Science. 1997 Apr 25; 276(5312):561-7.
    View in: PubMed
    Score: 0.022
  39. Fang G, Cech TR. Telomerase RNA localized in the replication band and spherical subnuclear organelles in hypotrichous ciliates. J Cell Biol. 1995 Jul; 130(2):243-53.
    View in: PubMed
    Score: 0.019
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

Copyright © 2025 The Regents of the University of Colorado, a body corporate. All rights reserved. (Harvard PROFILES RNS software version: 2.11.1)