 Connection
Kathryn Haskins to CD4-Positive T-Lymphocytes
This is a "connection" page, showing publications Kathryn Haskins has written about CD4-Positive T-Lymphocytes.
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Connection Strength |
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5.606 |
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Haskins K, Delong T, DiLisio JE, Baker RL. Hybrid Insulin Peptides as Antigens and Tolerogens for Pathogenic T Cells in Autoimmune Diabetes. Immunol Rev. 2026 Aug; 341(1):e70142.
Score: 0.609
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DiLisio JE, Beard KS, Neef T, Miller SD, Wenzlau JM, Nakayama M, D'Antonio MA, Jamison BL, Nicholson KS, Baker RL, Brunetti TM, Gapin L, Haskins K. Antigen-specific immunotherapy with a CD4+ T cell neoepitope restrains CD8+ T cell differentiation in murine pancreatic islet grafts. Nat Commun. 2026 Mar 24; 17(1).
Score: 0.594
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Baker RL, Jamison BL, Haskins K. Hybrid insulin peptides are neo-epitopes for CD4 T cells in autoimmune diabetes. Curr Opin Endocrinol Diabetes Obes. 2019 08; 26(4):195-200.
Score: 0.375
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Baker RL, Jamison BL, Wiles TA, Lindsay RS, Barbour G, Bradley B, Delong T, Friedman RS, Nakayama M, Haskins K. CD4 T Cells Reactive to Hybrid Insulin Peptides Are Indicators of Disease Activity in the NOD Mouse. Diabetes. 2018 09; 67(9):1836-1846.
Score: 0.348
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Wiles TA, Delong T, Baker RL, Bradley B, Barbour G, Powell RL, Reisdorph N, Haskins K. An insulin-IAPP hybrid peptide is an endogenous antigen for CD4 T cells in the non-obese diabetic mouse. J Autoimmun. 2017 03; 78:11-18.
Score: 0.310
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Delong T, Wiles TA, Baker RL, Bradley B, Barbour G, Reisdorph R, Armstrong M, Powell RL, Reisdorph N, Kumar N, Elso CM, DeNicola M, Bottino R, Powers AC, Harlan DM, Kent SC, Mannering SI, Haskins K. Pathogenic CD4 T cells in type 1 diabetes recognize epitopes formed by peptide fusion. Science. 2016 Feb 12; 351(6274):711-4.
Score: 0.295
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Baker RL, Bradley B, Wiles TA, Lindsay RS, Barbour G, Delong T, Friedman RS, Haskins K. Cutting Edge: Nonobese Diabetic Mice Deficient in Chromogranin A Are Protected from Autoimmune Diabetes. J Immunol. 2016 Jan 01; 196(1):39-43.
Score: 0.290
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Baker RL, Delong T, Barbour G, Bradley B, Nakayama M, Haskins K. Cutting edge: CD4 T cells reactive to an islet amyloid polypeptide peptide accumulate in the pancreas and contribute to disease pathogenesis in nonobese diabetic mice. J Immunol. 2013 Oct 15; 191(8):3990-4.
Score: 0.249
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Delong T, Baker RL, He J, Haskins K. Novel autoantigens for diabetogenic CD4 T cells in autoimmune diabetes. Immunol Res. 2013 Mar; 55(1-3):167-72.
Score: 0.240
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Haskins K, Cooke A. CD4 T cells and their antigens in the pathogenesis of autoimmune diabetes. Curr Opin Immunol. 2011 Dec; 23(6):739-45.
Score: 0.217
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Delong T, Baker RL, Reisdorph N, Reisdorph R, Powell RL, Armstrong M, Barbour G, Bradley B, Haskins K. Islet amyloid polypeptide is a target antigen for diabetogenic CD4+ T cells. Diabetes. 2011 Sep; 60(9):2325-30.
Score: 0.214
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Baker RL, Wagner DH, Haskins K. CD40 on NOD CD4 T cells contributes to their activation and pathogenicity. J Autoimmun. 2008 Dec; 31(4):385-92.
Score: 0.178
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Cantor J, Haskins K. Recruitment and activation of macrophages by pathogenic CD4 T cells in type 1 diabetes: evidence for involvement of CCR8 and CCL1. J Immunol. 2007 Nov 01; 179(9):5760-7.
Score: 0.166
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Wenzlau JM, Mangold K, Nicholson K, Dang M, Hohenstein AC, Douglas KS, DiLisio JE, Powell R, Delong T, Haskins K, Baker RL. A novel region of the insulin B9-23 sequence is targeted by a HIP-reactive diabetogenic T cell clone. Front Immunol. 2026; 17:1837267.
Score: 0.152
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Hohenstein AC, Gallegos JB, Dang M, Groegler J, Broncucia H, Tensun FA, Waugh K, Dong F, James EA, Speake C, Steck AK, Rewers MJ, Gottlieb PA, Haskins K, Delong T, Baker RL. Novel T-Cell Reactivities to Hybrid Insulin Peptides in Islet Autoantibody-Positive At-Risk Individuals. Diabetes. 2025 Jun 01; 74(6):933-942.
Score: 0.140
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Wenzlau JM, DiLisio JE, Barbour G, Dang M, Hohenstein AC, Nakayama M, Delong T, Baker RL, Haskins K. Insulin B-chain hybrid peptides are agonists for T cells reactive to insulin B:9-23 in autoimmune diabetes. Front Immunol. 2022; 13:926650.
Score: 0.116
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Jamison BL, DiLisio JE, Beard KS, Neef T, Bradley B, Goodman J, Gill RG, Miller SD, Baker RL, Haskins K. Tolerogenic Delivery of a Hybrid Insulin Peptide Markedly Prolongs Islet Graft Survival in the NOD Mouse. Diabetes. 2022 03 01; 71(3):483-496.
Score: 0.112
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Neef T, Ifergan I, Beddow S, Penaloza-MacMaster P, Haskins K, Shea LD, Podojil JR, Miller SD. Tolerance Induced by Antigen-Loaded PLG Nanoparticles Affects the Phenotype and Trafficking of Transgenic CD4+ and CD8+ T Cells. Cells. 2021 12 07; 10(12).
Score: 0.110
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Wiles TA, Hohenstein A, Landry LG, Dang M, Powell R, Guyer P, James EA, Nakayama M, Haskins K, Delong T, Baker RL. Characterization of Human CD4 T Cells Specific for a C-Peptide/C-Peptide Hybrid Insulin Peptide. Front Immunol. 2021; 12:668680.
Score: 0.106
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Peterson JD, Haskins K. Transfer of diabetes in the NOD-scid mouse by CD4 T-cell clones. Differential requirement for CD8 T-cells. Diabetes. 1996 Mar; 45(3):328-36.
Score: 0.074
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Viret C, Mahiddine K, Baker RL, Haskins K, Guerder S. The T Cell Repertoire-Diversifying Enzyme TSSP Contributes to Thymic Selection of Diabetogenic CD4 T Cell Specificities Reactive to ChgA and IAPP Autoantigens. J Immunol. 2015 Sep 01; 195(5):1964-73.
Score: 0.071
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Peterson JD, Pike B, Dallas-Pedretti A, Haskins K. Induction of diabetes with islet-specific T-cell clones is age dependent. Immunology. 1995 Jul; 85(3):455-60.
Score: 0.071
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Gottlieb PA, Delong T, Baker RL, Fitzgerald-Miller L, Wagner R, Cook G, Rewers MR, Michels A, Haskins K. Chromogranin A is a T cell antigen in human type 1 diabetes. J Autoimmun. 2014 May; 50:38-41.
Score: 0.063
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Cordova KN, Willis VC, Haskins K, Holers VM. A citrullinated fibrinogen-specific T cell line enhances autoimmune arthritis in a mouse model of rheumatoid arthritis. J Immunol. 2013 Feb 15; 190(4):1457-65.
Score: 0.060
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Delong T, Baker RL, He J, Barbour G, Bradley B, Haskins K. Diabetogenic T-cell clones recognize an altered peptide of chromogranin A. Diabetes. 2012 Dec; 61(12):3239-46.
Score: 0.058
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Baker RL, Mallevaey T, Gapin L, Haskins K. T cells interact with T cells via CD40-CD154 to promote autoimmunity in type 1 diabetes. Eur J Immunol. 2012 Mar; 42(3):672-80.
Score: 0.056
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Bradley BJ, Wang YY, Lafferty KJ, Haskins K. In vivo activity of an islet-reactive T-cell clone. J Autoimmun. 1990 Aug; 3(4):449-56.
Score: 0.050
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Groegler J, Mangold K, Nicholson K, Dang M, Wenzlau J, Beard KS, Hohenstein A, Powell R, Baker R, Haskins K, Matsuda J, Delong T. Strategic Reduction of Hybrid Insulin Peptide Formation Significantly Delays Diabetes Onset in NOD Mice. Diabetes. 2026 01 01; 75(1):115-123.
Score: 0.037
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Phillips JM, Haskins K, Cooke A. MAdCAM-1 is needed for diabetes development mediated by the T cell clone, BDC-2.5. Immunology. 2005 Dec; 116(4):525-31.
Score: 0.036
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Haskins K. Pathogenic T-cell clones in autoimmune diabetes: more lessons from the NOD mouse. Adv Immunol. 2005; 87:123-62.
Score: 0.034
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Pauza ME, Dobbs CM, He J, Patterson T, Wagner S, Anobile BS, Bradley BJ, Lo D, Haskins K. T-cell receptor transgenic response to an endogenous polymorphic autoantigen determines susceptibility to diabetes. Diabetes. 2004 Apr; 53(4):978-88.
Score: 0.032
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Stratmann T, Martin-Orozco N, Mallet-Designe V, Poirot L, McGavern D, Losyev G, Dobbs CM, Oldstone MB, Yoshida K, Kikutani H, Mathis D, Benoist C, Haskins K, Teyton L. Susceptible MHC alleles, not background genes, select an autoimmune T cell reactivity. J Clin Invest. 2003 Sep; 112(6):902-14.
Score: 0.031
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Crawford SA, Wiles TA, Wenzlau JM, Powell RL, Barbour G, Dang M, Groegler J, Barra JM, Burnette KS, Hohenstein AC, Baker RL, Tse HM, Haskins K, Delong T. Cathepsin D Drives the Formation of Hybrid Insulin Peptides Relevant to the Pathogenesis of Type 1 Diabetes. Diabetes. 2022 12 01; 71(12):2793-2803.
Score: 0.030
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Dobbs C, Haskins K. Comparison of a T cell clone and of T cells from a TCR transgenic mouse: TCR transgenic T cells specific for self-antigen are atypical. J Immunol. 2001 Feb 15; 166(4):2495-504.
Score: 0.026
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Arribas-Layton D, Guyer P, Delong T, Dang M, Chow IT, Speake C, Greenbaum CJ, Kwok WW, Baker RL, Haskins K, James EA. Hybrid Insulin Peptides Are Recognized by Human T Cells in the Context of DRB1*04:01. Diabetes. 2020 07; 69(7):1492-1502.
Score: 0.025
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Babon JA, DeNicola ME, Blodgett DM, Crèvecoeur I, Buttrick TS, Maehr R, Bottino R, Naji A, Kaddis J, Elyaman W, James EA, Haliyur R, Brissova M, Overbergh L, Mathieu C, Delong T, Haskins K, Pugliese A, Campbell-Thompson M, Mathews C, Atkinson MA, Powers AC, Harlan DM, Kent SC. Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes. Nat Med. 2016 12; 22(12):1482-1487.
Score: 0.019
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Gill RG, Haskins K. Molecular mechanisms underlying diabetes and other autoimmune diseases. Immunol Today. 1993 Feb; 14(2):49-51.
Score: 0.015
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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