 Connection
Charles Dinarello to Tumor Necrosis Factor-alpha
This is a "connection" page, showing publications Charles Dinarello has written about Tumor Necrosis Factor-alpha.
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8.259 |
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Dinarello CA. An expanding role for interleukin-1 blockade from gout to cancer. Mol Med. 2014 Dec 16; 20 Suppl 1:S43-58.
Score: 0.307
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Edwards CK, Bendele AM, Reznikov LI, Fantuzzi G, Chlipala ES, Li L, Moldawer LL, Mountz JD, Li YY, Dinarello CA. Soluble human p55 and p75 tumor necrosis factor receptors reverse spontaneous arthritis in transgenic mice expressing transmembrane tumor necrosis factor alpha. Arthritis Rheum. 2006 Sep; 54(9):2872-85.
Score: 0.173
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Dinarello CA. The paradox of pro-inflammatory cytokines in cancer. Cancer Metastasis Rev. 2006 Sep; 25(3):307-13.
Score: 0.173
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Dinarello CA. Differences between anti-tumor necrosis factor-alpha monoclonal antibodies and soluble TNF receptors in host defense impairment. J Rheumatol Suppl. 2005 Mar; 74:40-7.
Score: 0.155
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Kim SH, Han SY, Azam T, Yoon DY, Dinarello CA. Interleukin-32: a cytokine and inducer of TNFalpha. Immunity. 2005 Jan; 22(1):131-42.
Score: 0.154
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Reznikov LL, Waksman J, Azam T, Kim SH, Bufler P, Niwa T, Werman A, Zhang X, Pischetsrieder M, Shaldon S, Dinarello CA. Effect of advanced glycation end products on endotoxin-induced TNF-alpha, IL-1beta and IL-8 in human peripheral blood mononuclear cells. Clin Nephrol. 2004 May; 61(5):324-36.
Score: 0.147
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Ghezzi P, Fantuzzi G, Dinarello CA. Perspective: Daniela Novick, cytokines and their receptors. Front Immunol. 2023; 14:1160651.
Score: 0.137
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Dinarello CA. Setting the cytokine trap for autoimmunity. Nat Med. 2003 Jan; 9(1):20-2.
Score: 0.134
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Dinarello CA. Anti-cytokine therapies in response to systemic infection. J Investig Dermatol Symp Proc. 2001 Dec; 6(3):244-50.
Score: 0.124
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Li S, Jiang L, Beckmann K, Højen JF, Pessara U, Powers NE, de Graaf DM, Azam T, Lindenberger J, Eisenmesser EZ, Fischer S, Dinarello CA. A novel anti-human IL-1R7 antibody reduces IL-18-mediated inflammatory signaling. J Biol Chem. 2021 Jan-Jun; 296:100630.
Score: 0.119
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Frishman JI, Edwards CK, Sonnenberg MG, Kohno T, Cohen AM, Dinarello CA. Tumor necrosis factor (TNF)-alpha-induced interleukin-8 in human blood cultures discriminates neutralization by the p55 and p75 TNF soluble receptors. J Infect Dis. 2000 Dec; 182(6):1722-30.
Score: 0.115
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Dinarello CA. Proinflammatory cytokines. Chest. 2000 Aug; 118(2):503-8.
Score: 0.113
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Puren AJ, Fantuzzi G, Gu Y, Su MS, Dinarello CA. Interleukin-18 (IFNgamma-inducing factor) induces IL-8 and IL-1beta via TNFalpha production from non-CD14+ human blood mononuclear cells. J Clin Invest. 1998 Feb 01; 101(3):711-21.
Score: 0.095
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Dinarello CA. Blocking interleukin-1 and tumor necrosis factor in disease. Eur Cytokine Netw. 1997 Sep; 8(3):294-6.
Score: 0.092
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Dinarello CA. Role of pro- and anti-inflammatory cytokines during inflammation: experimental and clinical findings. J Biol Regul Homeost Agents. 1997 Jul-Sep; 11(3):91-103.
Score: 0.091
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Shapiro L, Dinarello CA. Hyperosmotic stress as a stimulant for proinflammatory cytokine production. Exp Cell Res. 1997 Mar 15; 231(2):354-62.
Score: 0.090
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Endres S, Whitaker RE, Ghorbani R, Meydani SN, Dinarello CA. Oral aspirin and ibuprofen increase cytokine-induced synthesis of IL-1 beta and of tumour necrosis factor-alpha ex vivo. Immunology. 1996 Feb; 87(2):264-70.
Score: 0.083
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Dinarello CA, Joosten LA. Inflammation in rheumatology in 2015: New tools to tackle inflammatory arthritis. Nat Rev Rheumatol. 2016 Feb; 12(2):78-80.
Score: 0.083
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Dinarello CA. Controlling the production of interleukin-1 and tumor necrosis factor in disease. Nutrition. 1995 Sep-Oct; 11(5 Suppl):695-7.
Score: 0.081
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Chernoff AE, Granowitz EV, Shapiro L, Vannier E, Lonnemann G, Angel JB, Kennedy JS, Rabson AR, Wolff SM, Dinarello CA. A randomized, controlled trial of IL-10 in humans. Inhibition of inflammatory cytokine production and immune responses. J Immunol. 1995 May 15; 154(10):5492-9.
Score: 0.079
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Li S, Neff CP, Barber K, Hong J, Luo Y, Azam T, Palmer BE, Fujita M, Garlanda C, Mantovani A, Kim S, Dinarello CA. Extracellular forms of IL-37 inhibit innate inflammation in vitro and in vivo but require the IL-1 family decoy receptor IL-1R8. Proc Natl Acad Sci U S A. 2015 Feb 24; 112(8):2497-502.
Score: 0.077
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Li S, Fossati G, Marchetti C, Modena D, Pozzi P, Reznikov LL, Moras ML, Azam T, Abbate A, Mascagni P, Dinarello CA. Specific inhibition of histone deacetylase 8 reduces gene expression and production of proinflammatory cytokines in vitro and in vivo. J Biol Chem. 2015 Jan 23; 290(4):2368-78.
Score: 0.076
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Wakabayashi G, Cannon JG, Gelfand JA, Clark BD, Aiura K, Burke JF, Wolff SM, Dinarello CA. Altered interleukin-1 and tumor necrosis factor production and secretion during pyrogenic tolerance to LPS in rabbits. Am J Physiol. 1994 Jul; 267(1 Pt 2):R329-36.
Score: 0.074
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Pereira BJ, Shapiro L, King AJ, Falagas ME, Strom JA, Dinarello CA. Plasma levels of IL-1 beta, TNF alpha and their specific inhibitors in undialyzed chronic renal failure, CAPD and hemodialysis patients. Kidney Int. 1994 Mar; 45(3):890-6.
Score: 0.073
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Tilg H, Vogel W, Wiedermann CJ, Shapiro L, Herold M, Judmaier G, Dinarello CA. Circulating interleukin-1 and tumor necrosis factor antagonists in liver disease. Hepatology. 1993 Nov; 18(5):1132-8.
Score: 0.071
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Aiura K, Gelfand JA, Burke JF, Thompson RC, Dinarello CA. Interleukin-1 (IL-1) receptor antagonist prevents Staphylococcus epidermidis-induced hypotension and reduces circulating levels of tumor necrosis factor and IL-1 beta in rabbits. Infect Immun. 1993 Aug; 61(8):3342-50.
Score: 0.070
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Coceani F, Lees J, Mancilla J, Belizario J, Dinarello CA. Interleukin-6 and tumor necrosis factor in cerebrospinal fluid: changes during pyrogen fever. Brain Res. 1993 May 28; 612(1-2):165-71.
Score: 0.069
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Joosten LA, Heinhuis B, Netea MG, Dinarello CA. Novel insights into the biology of interleukin-32. Cell Mol Life Sci. 2013 Oct; 70(20):3883-92.
Score: 0.068
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Dinarello CA. Interleukin-1 and tumor necrosis factor and their naturally occurring antagonists during hemodialysis. Kidney Int Suppl. 1992 Oct; 38:S68-77.
Score: 0.066
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Cannon JG, Friedberg JS, Gelfand JA, Tompkins RG, Burke JF, Dinarello CA. Circulating interleukin-1 beta and tumor necrosis factor-alpha concentrations after burn injury in humans. Crit Care Med. 1992 Oct; 20(10):1414-9.
Score: 0.066
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Dinarello CA. Interleukin-1 and tumor necrosis factor: effector cytokines in autoimmune diseases. Semin Immunol. 1992 Jun; 4(3):133-45.
Score: 0.064
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Dinarello CA. Inflammatory cytokines: interleukin-1 and tumor necrosis factor as effector molecules in autoimmune diseases. Curr Opin Immunol. 1991 Dec; 3(6):941-8.
Score: 0.062
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Bedrosian I, Sofia RD, Wolff SM, Dinarello CA. Taurolidine, an analogue of the amino acid taurine, suppresses interleukin 1 and tumor necrosis factor synthesis in human peripheral blood mononuclear cells. Cytokine. 1991 Nov; 3(6):568-75.
Score: 0.062
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Vannier E, Miller LC, Dinarello CA. Histamine suppresses gene expression and synthesis of tumor necrosis factor alpha via histamine H2 receptors. J Exp Med. 1991 Jul 01; 174(1):281-4.
Score: 0.060
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Dinarello CA. The proinflammatory cytokines interleukin-1 and tumor necrosis factor and treatment of the septic shock syndrome. J Infect Dis. 1991 Jun; 163(6):1177-84.
Score: 0.060
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Wakabayashi G, Gelfand JA, Jung WK, Connolly RJ, Burke JF, Dinarello CA. Staphylococcus epidermidis induces complement activation, tumor necrosis factor and interleukin-1, a shock-like state and tissue injury in rabbits without endotoxemia. Comparison to Escherichia coli. J Clin Invest. 1991 Jun; 87(6):1925-35.
Score: 0.060
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Belizario JE, Dinarello CA. Interleukin 1, interleukin 6, tumor necrosis factor, and transforming growth factor beta increase cell resistance to tumor necrosis factor cytotoxicity by growth arrest in the G1 phase of the cell cycle. Cancer Res. 1991 May 01; 51(9):2379-85.
Score: 0.060
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Furlan A, Monzani V, Reznikov LL, Leoni F, Fossati G, Modena D, Mascagni P, Dinarello CA. Pharmacokinetics, safety and inducible cytokine responses during a phase 1 trial of the oral histone deacetylase inhibitor ITF2357 (givinostat). Mol Med. 2011 May-Jun; 17(5-6):353-62.
Score: 0.059
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Sirko SP, Schindler R, Doyle MJ, Weisman SM, Dinarello CA. Transcription, translation and secretion of interleukin 1 and tumor necrosis factor: effects of tebufelone, a dual cyclooxygenase/5-lipoxygenase inhibitor. Eur J Immunol. 1991 Feb; 21(2):243-50.
Score: 0.059
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Heinhuis B, Koenders MI, van Riel PL, van de Loo FA, Dinarello CA, Netea MG, van den Berg WB, Joosten LA. Tumour necrosis factor alpha-driven IL-32 expression in rheumatoid arthritis synovial tissue amplifies an inflammatory cascade. Ann Rheum Dis. 2011 Apr; 70(4):660-7.
Score: 0.058
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Miller LC, Isa S, LoPreste G, Schaller JG, Dinarello CA. Neonatal interleukin-1 beta, interleukin-6, and tumor necrosis factor: cord blood levels and cellular production. J Pediatr. 1990 Dec; 117(6):961-5.
Score: 0.058
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Hauser SL, Doolittle TH, Lincoln R, Brown RH, Dinarello CA. Cytokine accumulations in CSF of multiple sclerosis patients: frequent detection of interleukin-1 and tumor necrosis factor but not interleukin-6. Neurology. 1990 Nov; 40(11):1735-9.
Score: 0.058
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Schindler R, Gelfand JA, Dinarello CA. Recombinant C5a stimulates transcription rather than translation of interleukin-1 (IL-1) and tumor necrosis factor: translational signal provided by lipopolysaccharide or IL-1 itself. Blood. 1990 Oct 15; 76(8):1631-8.
Score: 0.057
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Zucali JR, Morse C, Dinarello CA. The role of protein kinase C in interleukin 1 and tumor necrosis factor alpha induction of fibroblasts to produce and release granulocyte-macrophage colony-stimulating activity. Exp Hematol. 1990 Sep; 18(8):888-92.
Score: 0.057
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Ikejima T, Okusawa S, Ghezzi P, van der Meer JW, Dinarello CA. Interleukin-1 induces tumor necrosis factor (TNF) in human peripheral blood mononuclear cells in vitro and a circulating TNF-like activity in rabbits. J Infect Dis. 1990 Jul; 162(1):215-23.
Score: 0.056
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Schindler R, Mancilla J, Endres S, Ghorbani R, Clark SC, Dinarello CA. Correlations and interactions in the production of interleukin-6 (IL-6), IL-1, and tumor necrosis factor (TNF) in human blood mononuclear cells: IL-6 suppresses IL-1 and TNF. Blood. 1990 Jan 01; 75(1):40-7.
Score: 0.054
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Schindler R, Lonnemann G, Shaldon S, Koch KM, Dinarello CA. Transcription, not synthesis, of interleukin-1 and tumor necrosis factor by complement. Kidney Int. 1990 Jan; 37(1):85-93.
Score: 0.054
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Endres S, Cannon JG, Ghorbani R, Dempsey RA, Sisson SD, Lonnemann G, Van der Meer JW, Wolff SM, Dinarello CA. In vitro production of IL 1 beta, IL 1 alpha, TNF and IL2 in healthy subjects: distribution, effect of cyclooxygenase inhibition and evidence of independent gene regulation. Eur J Immunol. 1989 Dec; 19(12):2327-33.
Score: 0.054
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Dinarello CA. The endogenous pyrogens in host-defense interactions. Hosp Pract (Off Ed). 1989 Nov 15; 24(11):111-5, 118, 121 passim.
Score: 0.054
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Silliman CC, Kelher MR, Gamboni-Robertson F, Hamiel C, England KM, Dinarello CA, Wyman TH, Khan SY, McLaughlin NJ, Bercovitz RS, Banerjee A. Tumor necrosis factor-alpha causes release of cytosolic interleukin-18 from human neutrophils. Am J Physiol Cell Physiol. 2010 Mar; 298(3):C714-24.
Score: 0.054
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Hong J, Bae S, Kang Y, Yoon D, Bai X, Chan ED, Azam T, Dinarello CA, Lee S, Her E, Rho G, Kim S. Suppressing IL-32 in monocytes impairs the induction of the proinflammatory cytokines TNFalpha and IL-1beta. Cytokine. 2010 Feb; 49(2):171-6.
Score: 0.054
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Lonnemann G, Endres S, Van der Meer JW, Cannon JG, Koch KM, Dinarello CA. Differences in the synthesis and kinetics of release of interleukin 1 alpha, interleukin 1 beta and tumor necrosis factor from human mononuclear cells. Eur J Immunol. 1989 Sep; 19(9):1531-6.
Score: 0.053
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van der Meer JH, Netea MG, Dinarello CA. Modulation of muramyl dipeptide stimulation of cytokine production by blood components. Clin Exp Immunol. 2009 Jun; 156(3):428-33.
Score: 0.052
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Pott GB, Chan ED, Dinarello CA, Shapiro L. Alpha-1-antitrypsin is an endogenous inhibitor of proinflammatory cytokine production in whole blood. J Leukoc Biol. 2009 May; 85(5):886-95.
Score: 0.051
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Schindler R, Dinarello CA. A method for removing interleukin-1- and tumor necrosis factor-inducing substances from bacterial cultures by ultrafiltration with polysulfone. J Immunol Methods. 1989 Jan 17; 116(2):159-65.
Score: 0.051
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Dinarello CA, Okusawa S, Gelfand JA. Interleukin-1 induces a shock-like state in rabbits: synergism with tumor necrosis factor and the effect of cyclooxygenase inhibition. Prog Clin Biol Res. 1989; 286:243-63.
Score: 0.051
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van der Meer JW, Rubin RH, Pasternack M, Medearis DN, Lynch P, Dinarello CA. The in vivo and in vitro effects of interleukin-1 and tumor necrosis factor on murine cytomegalovirus infection. Biotherapy. 1989; 1(3):227-31.
Score: 0.051
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Schindler R, Lonnemann G, Shaldon S, Koch KM, Dinarello CA. Induction of interleukin-1 and tumor necrosis factor during in vitro hemodialysis with different membranes. Contrib Nephrol. 1989; 74:58-65.
Score: 0.051
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Dinarello CA, Okusawa S, Gelfand JA. Interleukin-1 induces a shock-like state in rabbits: synergism with tumor necrosis factor and the effect of ibuprofen. Prog Clin Biol Res. 1989; 299:203-15.
Score: 0.051
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Endres S, Ghorbani R, Lonnemann G, van der Meer JW, Dinarello CA. Measurement of immunoreactive interleukin-1 beta from human mononuclear cells: optimization of recovery, intrasubject consistency, and comparison with interleukin-1 alpha and tumor necrosis factor. Clin Immunol Immunopathol. 1988 Dec; 49(3):424-38.
Score: 0.050
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Ikejima T, Okusawa S, van der Meer JW, Dinarello CA. Induction by toxic-shock-syndrome toxin-1 of a circulating tumor necrosis factor-like substance in rabbits and of immunoreactive tumor necrosis factor and interleukin-1 from human mononuclear cells. J Infect Dis. 1988 Nov; 158(5):1017-25.
Score: 0.050
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Mier JW, Vachino G, van der Meer JW, Numerof RP, Adams S, Cannon JG, Bernheim HA, Atkins MB, Parkinson DR, Dinarello CA. Induction of circulating tumor necrosis factor (TNF alpha) as the mechanism for the febrile response to interleukin-2 (IL-2) in cancer patients. J Clin Immunol. 1988 Nov; 8(6):426-36.
Score: 0.050
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Sisson SD, Dinarello CA. Production of interleukin-1 alpha, interleukin-1 beta and tumor necrosis factor by human mononuclear cells stimulated with granulocyte-macrophage colony-stimulating factor. Blood. 1988 Oct; 72(4):1368-74.
Score: 0.050
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Cha J, Wang Z, Ao L, Zou N, Dinarello CA, Banerjee A, Fullerton DA, Meng X. Cytokines link Toll-like receptor 4 signaling to cardiac dysfunction after global myocardial ischemia. Ann Thorac Surg. 2008 May; 85(5):1678-85.
Score: 0.048
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Okusawa S, Gelfand JA, Ikejima T, Connolly RJ, Dinarello CA. Interleukin 1 induces a shock-like state in rabbits. Synergism with tumor necrosis factor and the effect of cyclooxygenase inhibition. J Clin Invest. 1988 Apr; 81(4):1162-72.
Score: 0.048
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van der Meer JW, Endres S, Lonnemann G, Cannon JG, Ikejima T, Okusawa S, Gelfand JA, Dinarello CA. Concentrations of immunoreactive human tumor necrosis factor alpha produced by human mononuclear cells in vitro. J Leukoc Biol. 1988 Mar; 43(3):216-23.
Score: 0.048
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Zucali JR, Broxmeyer HE, Gross MA, Dinarello CA. Recombinant human tumor necrosis factors alpha and beta stimulate fibroblasts to produce hemopoietic growth factors in vitro. J Immunol. 1988 Feb 01; 140(3):840-4.
Score: 0.048
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Saavedra MT, Patterson AD, West J, Randell SH, Riches DW, Malcolm KC, Cool CD, Nick JA, Dinarello CA. Abrogation of anti-inflammatory transcription factor LKLF in neutrophil-dominated airways. Am J Respir Cell Mol Biol. 2008 Jun; 38(6):679-88.
Score: 0.048
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Dinarello CA. Endogenous pyrogens. Methods Enzymol. 1988; 163:495-510.
Score: 0.047
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Conti P, Reale M, Fiore S, Cancelli A, Angeletti PU, Dinarello CA. Recombinant interleukin 1 and tumor necrosis factor acting in synergy to release thromboxane, 6-KETO-PGF1 alpha and PGE2 by human neutrophils. Scand J Rheumatol Suppl. 1988; 75:318-24.
Score: 0.047
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Dinarello CA. The biology of interleukin 1 and comparison to tumor necrosis factor. Immunol Lett. 1987 Dec; 16(3-4):227-31.
Score: 0.047
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Movat HZ, Burrowes CE, Cybulsky MI, Dinarello CA. Acute inflammation and a Shwartzman-like reaction induced by interleukin-1 and tumor necrosis factor. Synergistic action of the cytokines in the induction of inflammation and microvascular injury. Am J Pathol. 1987 Dec; 129(3):463-76.
Score: 0.047
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Ao L, Song Y, Fullerton DA, Dinarello CA, Meng X. The interaction between myocardial depressant factors in endotoxemic cardiac dysfunction: role of TNF-alpha in TLR4-mediated ICAM-1 expression. Cytokine. 2007 Jun; 38(3):124-9.
Score: 0.046
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Cybulsky MI, Movat HZ, Dinarello CA. Role of interleukin-1 and tumour necrosis factor-alpha in acute inflammation. Ann Inst Pasteur Immunol. 1987 May-Jun; 138(3):505-12.
Score: 0.045
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Meldrum KK, Misseri R, Metcalfe P, Dinarello CA, Hile KL, Meldrum DR. TNF-alpha neutralization ameliorates obstruction-induced renal fibrosis and dysfunction. Am J Physiol Regul Integr Comp Physiol. 2007 Apr; 292(4):R1456-64.
Score: 0.044
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Morris AM, Sennello JA, Fayad RA, Eckel RH, Dinarello CA, Fantuzzi G. T cell-mediated hepatic inflammation modulates adiponectin levels in mice: role of tumor necrosis factor alpha. Metabolism. 2006 Apr; 55(4):555-9.
Score: 0.042
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Lewis EC, Shapiro L, Bowers OJ, Dinarello CA. Alpha1-antitrypsin monotherapy prolongs islet allograft survival in mice. Proc Natl Acad Sci U S A. 2005 Aug 23; 102(34):12153-8.
Score: 0.040
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Fayad R, Sennello JA, Kim SH, Pini M, Dinarello CA, Fantuzzi G. Induction of thymocyte apoptosis by systemic administration of concanavalin A in mice: role of TNF-alpha, IFN-gamma and glucocorticoids. Eur J Immunol. 2005 Aug; 35(8):2304-12.
Score: 0.040
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Dinarello CA. Blocking IL-1 in systemic inflammation. J Exp Med. 2005 May 02; 201(9):1355-9.
Score: 0.039
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Misseri R, Meldrum DR, Dinarello CA, Dagher P, Hile KL, Rink RC, Meldrum KK. TNF-alpha mediates obstruction-induced renal tubular cell apoptosis and proapoptotic signaling. Am J Physiol Renal Physiol. 2005 Feb; 288(2):F406-11.
Score: 0.038
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Dinarello CA. Therapeutic strategies to reduce IL-1 activity in treating local and systemic inflammation. Curr Opin Pharmacol. 2004 Aug; 4(4):378-85.
Score: 0.037
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Schottelius AJ, Moldawer LL, Dinarello CA, Asadullah K, Sterry W, Edwards CK. Biology of tumor necrosis factor-alpha- implications for psoriasis. Exp Dermatol. 2004 Apr; 13(4):193-222.
Score: 0.036
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Stuyt RJ, Kim SH, Reznikov LL, Fantuzzi G, Novick D, Rubinstein M, Kullberg BJ, van der Meer JW, Dinarello CA, Netea MG. Regulation of Staphylococcus epidermidis-induced IFN-gamma in whole human blood: the role of endogenous IL-18, IL-12, IL-1, and TNF. Cytokine. 2003 Jan 21; 21(2):65-73.
Score: 0.034
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Netea MG, Stuyt RJ, Kim SH, Van der Meer JW, Kullberg BJ, Dinarello CA. The role of endogenous interleukin (IL)-18, IL-12, IL-1beta, and tumor necrosis factor-alpha in the production of interferon-gamma induced by Candida albicans in human whole-blood cultures. J Infect Dis. 2002 Apr 01; 185(7):963-70.
Score: 0.032
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Siegmund B, Fantuzzi G, Rieder F, Gamboni-Robertson F, Lehr HA, Hartmann G, Dinarello CA, Endres S, Eigler A. Neutralization of interleukin-18 reduces severity in murine colitis and intestinal IFN-gamma and TNF-alpha production. Am J Physiol Regul Integr Comp Physiol. 2001 Oct; 281(4):R1264-73.
Score: 0.031
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Stuyt RJ, Netea MG, Kim SH, Novick D, Rubinstein M, Kullberg BJ, Van der Meer JW, Dinarello CA. Differential roles of interleukin-18 (IL-18) and IL12 for induction of gamma interferon by staphylococcal cell wall components and superantigens. Infect Immun. 2001 Aug; 69(8):5025-30.
Score: 0.030
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Heimbach JK, Reznikov LL, Calkins CM, Robinson TN, Dinarello CA, Harken AH, Meng X. TNF receptor I is required for induction of macrophage heat shock protein 70. Am J Physiol Cell Physiol. 2001 Jul; 281(1):C241-7.
Score: 0.030
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Knotek M, Rogachev B, Wang W, Ecder T, Melnikov V, Gengaro PE, Esson M, Edelstein CL, Dinarello CA, Schrier RW. Endotoxemic renal failure in mice: Role of tumor necrosis factor independent of inducible nitric oxide synthase. Kidney Int. 2001 Jun; 59(6):2243-9.
Score: 0.030
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Rønholt K, Nielsen AL, Johansen C, Vestergaard C, Fauerbye A, López-Vales R, Dinarello CA, Iversen L. IL-37 Expression Is Downregulated in Lesional Psoriasis Skin. Immunohorizons. 2020 11 25; 4(11):754-761.
Score: 0.029
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Netea MG, Puren AJ, Dinarello CA. A short course of oral aspirin increases IL-18-induced interferon-gamma production in whole blood cultures. Eur Cytokine Netw. 2000 Sep; 11(3):379-82.
Score: 0.028
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Netea MG, Fantuzzi G, Kullberg BJ, Stuyt RJ, Pulido EJ, McIntyre RC, Joosten LA, Van der Meer JW, Dinarello CA. Neutralization of IL-18 reduces neutrophil tissue accumulation and protects mice against lethal Escherichia coli and Salmonella typhimurium endotoxemia. J Immunol. 2000 Mar 01; 164(5):2644-9.
Score: 0.027
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Faggioni R, Jones-Carson J, Reed DA, Dinarello CA, Feingold KR, Grunfeld C, Fantuzzi G. Leptin-deficient (ob/ob) mice are protected from T cell-mediated hepatotoxicity: role of tumor necrosis factor alpha and IL-18. Proc Natl Acad Sci U S A. 2000 Feb 29; 97(5):2367-72.
Score: 0.027
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Vidal-Vanaclocha F, Fantuzzi G, Mendoza L, Fuentes AM, Anasagasti MJ, Martín J, Carrascal T, Walsh P, Reznikov LL, Kim SH, Novick D, Rubinstein M, Dinarello CA. IL-18 regulates IL-1beta-dependent hepatic melanoma metastasis via vascular cell adhesion molecule-1. Proc Natl Acad Sci U S A. 2000 Jan 18; 97(2):734-9.
Score: 0.027
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Cain BS, Meldrum DR, Dinarello CA, Meng X, Joo KS, Banerjee A, Harken AH. Tumor necrosis factor-alpha and interleukin-1beta synergistically depress human myocardial function. Crit Care Med. 1999 Jul; 27(7):1309-18.
Score: 0.026
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Cain BS, Meldrum DR, Meng X, Dinarello CA, Shames BD, Banerjee A, Harken AH. p38 MAPK inhibition decreases TNF-alpha production and enhances postischemic human myocardial function. J Surg Res. 1999 May 01; 83(1):7-12.
Score: 0.026
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Selzman CH, Shames BD, Reznikov LL, Miller SA, Meng X, Barton HA, Werman A, Harken AH, Dinarello CA, Banerjee A. Liposomal delivery of purified inhibitory-kappaBalpha inhibits tumor necrosis factor-alpha-induced human vascular smooth muscle proliferation. Circ Res. 1999 Apr 30; 84(8):867-75.
Score: 0.026
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Dinarello CA. Cytokines as endogenous pyrogens. J Infect Dis. 1999 Mar; 179 Suppl 2:S294-304.
Score: 0.026
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Kaplanov I, Carmi Y, Kornetsky R, Shemesh A, Shurin GV, Shurin MR, Dinarello CA, Voronov E, Apte RN. Blocking IL-1ß reverses the immunosuppression in mouse breast cancer and synergizes with anti-PD-1 for tumor abrogation. Proc Natl Acad Sci U S A. 2019 01 22; 116(4):1361-1369.
Score: 0.025
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Puren AJ, Razeghi P, Fantuzzi G, Dinarello CA. Interleukin-18 enhances lipopolysaccharide-induced interferon-gamma production in human whole blood cultures. J Infect Dis. 1998 Dec; 178(6):1830-4.
Score: 0.025
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Meldrum DR, Dinarello CA, Shames BD, Cleveland JC, Cain BS, Banerjee A, Meng X, Harken AH. Ischemic preconditioning decreases postischemic myocardial tumor necrosis factor-alpha production. Potential ultimate effector mechanism of preconditioning. Circulation. 1998 Nov 10; 98(19 Suppl):II214-8; discussion II218-9.
Score: 0.025
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Shapiro L, Puren AJ, Barton HA, Novick D, Peskind RL, Shenkar R, Gu Y, Su MS, Dinarello CA. Interleukin 18 stimulates HIV type 1 in monocytic cells. Proc Natl Acad Sci U S A. 1998 Oct 13; 95(21):12550-5.
Score: 0.025
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Fraenkel L, Roubenoff R, LaValley M, McAlindon T, Chaisson C, Evans S, Harris T, Dinarello CA, Felson DT. The association of peripheral monocyte derived interleukin 1beta (IL-1beta), IL-1 receptor antagonist, and tumor necrosis factor-alpha with osteoarthritis in the elderly. J Rheumatol. 1998 Sep; 25(9):1820-6.
Score: 0.025
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Meldrum DR, Meng X, Dinarello CA, Ayala A, Cain BS, Shames BD, Ao L, Banerjee A, Harken AH. Human myocardial tissue TNFalpha expression following acute global ischemia in vivo. J Mol Cell Cardiol. 1998 Sep; 30(9):1683-9.
Score: 0.025
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Meldrum DR, Dinarello CA, Cleveland JC, Cain BS, Shames BD, Meng X, Harken AH. Hydrogen peroxide induces tumor necrosis factor alpha-mediated cardiac injury by a P38 mitogen-activated protein kinase-dependent mechanism. Surgery. 1998 Aug; 124(2):291-6; discussion 297.
Score: 0.025
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Shapiro L, Heidenreich KA, Meintzer MK, Dinarello CA. Role of p38 mitogen-activated protein kinase in HIV type 1 production in vitro. Proc Natl Acad Sci U S A. 1998 Jun 23; 95(13):7422-6.
Score: 0.024
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Cain BS, Meldrum DR, Dinarello CA, Meng X, Banerjee A, Harken AH. Adenosine reduces cardiac TNF-alpha production and human myocardial injury following ischemia-reperfusion. J Surg Res. 1998 May; 76(2):117-23.
Score: 0.024
-
Damen MSMA, Dos Santos JC, Hermsen R, Adam van der Vliet J, Netea MG, Riksen NP, Dinarello CA, Joosten LAB, Heinhuis B. Interleukin-32 upregulates the expression of ABCA1 and ABCG1 resulting in reduced intracellular lipid concentrations in primary human hepatocytes. Atherosclerosis. 2018 04; 271:193-202.
Score: 0.024
-
Roubenoff R, Harris TB, Abad LW, Wilson PW, Dallal GE, Dinarello CA. Monocyte cytokine production in an elderly population: effect of age and inflammation. J Gerontol A Biol Sci Med Sci. 1998 Jan; 53(1):M20-6.
Score: 0.024
-
Dinarello CA. Proinflammatory and anti-inflammatory cytokines as mediators in the pathogenesis of septic shock. Chest. 1997 Dec; 112(6 Suppl):321S-329S.
Score: 0.024
-
Mühl H, Dinarello CA. Macrophage inflammatory protein-1 alpha production in lipopolysaccharide-stimulated human adherent blood mononuclear cells is inhibited by the nitric oxide synthase inhibitor N(G)-monomethyl-L-arginine. J Immunol. 1997 Nov 15; 159(10):5063-9.
Score: 0.023
-
Kanni T, Argyropoulou M, Spyridopoulos T, Pistiki A, Stecher M, Dinarello CA, Simard J, Giamarellos-Bourboulis EJ. MABp1 Targeting IL-1a for Moderate to Severe Hidradenitis Suppurativa Not Eligible for Adalimumab: A Randomized Study. J Invest Dermatol. 2018 04; 138(4):795-801.
Score: 0.023
-
Fantuzzi G, Sacco S, Ghezzi P, Dinarello CA. Physiological and cytokine responses in IL-1 beta-deficient mice after zymosan-induced inflammation. Am J Physiol. 1997 Jul; 273(1 Pt 2):R400-6.
Score: 0.023
-
Aiura K, Clark BD, Dinarello CA, Margolis NH, Kaplanski G, Burke JF, Tompkins RG, Gelfand JA. Interaction with autologous platelets multiplies interleukin-1 and tumor necrosis factor production in mononuclear cells. J Infect Dis. 1997 Jan; 175(1):123-9.
Score: 0.022
-
Rall LC, Rosen CJ, Dolnikowski G, Hartman WJ, Lundgren N, Abad LW, Dinarello CA, Roubenoff R. Protein metabolism in rheumatoid arthritis and aging. Effects of muscle strength training and tumor necrosis factor alpha. Arthritis Rheum. 1996 Jul; 39(7):1115-24.
Score: 0.021
-
Takabayashi T, Vannier E, Clark BD, Margolis NH, Dinarello CA, Burke JF, Gelfand JA. A new biologic role for C3a and C3a desArg: regulation of TNF-alpha and IL-1 beta synthesis. J Immunol. 1996 May 01; 156(9):3455-60.
Score: 0.021
-
Granowitz EV, Saget BM, Angel JB, Wang MZ, Wang A, Dinarello CA, Skolnik PR. Soluble tumor necrosis factor receptors inhibit phorbol myristate acetate and cytokine-induced HIV-1 expression chronically infected U1 cells. J Acquir Immune Defic Syndr Hum Retrovirol. 1996 Apr 15; 11(5):430-7.
Score: 0.021
-
Dinarello CA. Cytokines as mediators in the pathogenesis of septic shock. Curr Top Microbiol Immunol. 1996; 216:133-65.
Score: 0.021
-
Pomianek MJ, Colton CK, Dinarello CA, Miller LC. Synthesis of tumor necrosis factor alpha and interleukin-1 receptor antagonist, but not interleukin-1, by human mononuclear cells is enhanced by exposure of whole blood to shear stress. ASAIO J. 1996 Jan-Feb; 42(1):52-9.
Score: 0.021
-
Dinarello CA, Roubenoff R. George Clowes' classic paper and the search for "muscle proteolysis factor". Nutrition. 1996 Jan; 12(1):67-8.
Score: 0.021
-
Angel JB, Saget BM, Walsh SP, Greten TF, Dinarello CA, Skolnik PR, Endres S. Rolipram, a specific type IV phosphodiesterase inhibitor, is a potent inhibitor of HIV-1 replication. AIDS. 1995 Oct; 9(10):1137-44.
Score: 0.020
-
Schindler R, Dinarello CA, Koch KM. Angiotensin-converting-enzyme inhibitors suppress synthesis of tumour necrosis factor and interleukin 1 by human peripheral blood mononuclear cells. Cytokine. 1995 Aug; 7(6):526-33.
Score: 0.020
-
Angel JB, Saget BM, Wang MZ, Wang A, Dinarello CA, Skolnik PR. Interleukin-10 enhances human immunodeficiency virus type 1 expression in a chronically infected promonocytic cell line (U1) by a tumor necrosis factor alpha-independent mechanism. J Interferon Cytokine Res. 1995 Jun; 15(6):575-84.
Score: 0.020
-
Bai X, Shang S, Henao-Tamayo M, Basaraba RJ, Ovrutsky AR, Matsuda JL, Takeda K, Chan MM, Dakhama A, Kinney WH, Trostel J, Bai A, Honda JR, Achcar R, Hartney J, Joosten LA, Kim SH, Orme I, Dinarello CA, Ordway DJ, Chan ED. Human IL-32 expression protects mice against a hypervirulent strain of Mycobacterium tuberculosis. Proc Natl Acad Sci U S A. 2015 Apr 21; 112(16):5111-6.
Score: 0.020
-
Lonnemann G, Engler-Blum G, Müller GA, Koch KM, Dinarello CA. Cytokines in human renal interstitial fibrosis. II. Intrinsic interleukin (IL)-1 synthesis and IL-1-dependent production of IL-6 and IL-8 by cultured kidney fibroblasts. Kidney Int. 1995 Mar; 47(3):845-54.
Score: 0.019
-
Tilg H, Vogel W, Dinarello CA. Interferon-alpha induces circulating tumor necrosis factor receptor p55 in humans. Blood. 1995 Jan 15; 85(2):433-5.
Score: 0.019
-
Vogels MT, Mensink EJ, Ye K, Boerman OC, Verschueren CM, Dinarello CA, van der Meer JW. Differential gene expression for IL-1 receptor antagonist, IL-1, and TNF receptors and IL-1 and TNF synthesis may explain IL-1-induced resistance to infection. J Immunol. 1994 Dec 15; 153(12):5772-80.
Score: 0.019
-
Dinarello CA. The biological properties of interleukin-1. Eur Cytokine Netw. 1994 Nov-Dec; 5(6):517-31.
Score: 0.019
-
Roubenoff R, Roubenoff RA, Cannon JG, Kehayias JJ, Zhuang H, Dawson-Hughes B, Dinarello CA, Rosenberg IH. Rheumatoid cachexia: cytokine-driven hypermetabolism accompanying reduced body cell mass in chronic inflammation. J Clin Invest. 1994 Jun; 93(6):2379-86.
Score: 0.018
-
Tilg H, Shapiro L, Vannier E, Poutsiaka DD, Trehu E, Atkins MB, Dinarello CA, Mier JW. Induction of circulating antagonists to IL-1 and TNF by IL-2 administration and their effects on IL-2 induced cytokine production in vitro. J Immunol. 1994 Mar 15; 152(6):3189-98.
Score: 0.018
-
Santos AA, Browning JL, Scheltinga MR, Lynch EA, Brown EF, Lawton P, Chambers E, Dougas I, Benjamin CD, Dinarello CA, et al. Are events after endotoxemia related to circulating phospholipase A2? Ann Surg. 1994 Feb; 219(2):183-92.
Score: 0.018
-
Latini R, Bianchi M, Correale E, Dinarello CA, Fantuzzi G, Fresco C, Maggioni AP, Mengozzi M, Romano S, Shapiro L, et al. Cytokines in acute myocardial infarction: selective increase in circulating tumor necrosis factor, its soluble receptor, and interleukin-1 receptor antagonist. J Cardiovasc Pharmacol. 1994 Jan; 23(1):1-6.
Score: 0.018
-
Dinarello CA. Blocking interleukin-1 receptors. Int J Clin Lab Res. 1994; 24(2):61-79.
Score: 0.018
-
Dinarello CA. Interleukin-1. Adv Pharmacol. 1994; 25:21-51.
Score: 0.018
-
Endres S, Meydani SN, Ghorbani R, Schindler R, Dinarello CA. Dietary supplementation with n-3 fatty acids suppresses interleukin-2 production and mononuclear cell proliferation. J Leukoc Biol. 1993 Dec; 54(6):599-603.
Score: 0.018
-
Shapiro L, Clark BD, Orencole SF, Poutsiaka DD, Granowitz EV, Dinarello CA. Detection of tumor necrosis factor soluble receptor p55 in blood samples from healthy and endotoxemic humans. J Infect Dis. 1993 Jun; 167(6):1344-50.
Score: 0.017
-
Lee S, Lee Y, Hong K, Hong J, Bae S, Choi J, Jhun H, Kwak A, Kim E, Jo S, Dinarello CA, Kim S. Effect of recombinant a1-antitrypsin Fc-fused (AAT-Fc)protein on the inhibition of inflammatory cytokine production and streptozotocin-induced diabetes. Mol Med. 2013 May 20; 19:65-71.
Score: 0.017
-
Dinarello CA, Gelfand JA, Wolff SM. Anticytokine strategies in the treatment of the systemic inflammatory response syndrome. JAMA. 1993 Apr 14; 269(14):1829-35.
Score: 0.017
-
Kaplan E, Dinarello CA, Wakabayashi G, Burke JF, Connolly RS, Gelfand JA. Interleukin-1 pretreatment protects against endotoxin-induced hypotension in rabbits: association with decreased tumor necrosis factor levels. J Infect Dis. 1993 Jan; 167(1):244-7.
Score: 0.017
-
Nerad JL, Griffiths JK, Van der Meer JW, Endres S, Poutsiaka DD, Keusch GT, Bennish M, Salam MA, Dinarello CA, Cannon JG. Interleukin-1 beta (IL-1 beta), IL-1 receptor antagonist, and TNF alpha production in whole blood. J Leukoc Biol. 1992 Dec; 52(6):687-92.
Score: 0.017
-
Memon RA, Feingold KR, Moser AH, Doerrler W, Adi S, Dinarello CA, Grunfeld C. Differential effects of interleukin-1 and tumor necrosis factor on ketogenesis. Am J Physiol. 1992 Aug; 263(2 Pt 1):E301-9.
Score: 0.016
-
Dinarello CA. Role of interleukin-1 in infectious diseases. Immunol Rev. 1992 Jun; 127:119-46.
Score: 0.016
-
Ho JL, Badaró R, Schwartz A, Dinarello CA, Gelfand JA, Sobel J, Barral A, Netto MB, Carvalho EM, Reed SG, et al. Diminished in vitro production of interleukin-1 and tumor necrosis factor-alpha during acute visceral leishmaniasis and recovery after therapy. J Infect Dis. 1992 Jun; 165(6):1094-102.
Score: 0.016
-
Granowitz EV, Clark BD, Vannier E, Callahan MV, Dinarello CA. Effect of interleukin-1 (IL-1) blockade on cytokine synthesis: I. IL-1 receptor antagonist inhibits IL-1-induced cytokine synthesis and blocks the binding of IL-1 to its type II receptor on human monocytes. Blood. 1992 May 01; 79(9):2356-63.
Score: 0.016
-
Granowitz EV, Vannier E, Poutsiaka DD, Dinarello CA. Effect of interleukin-1 (IL-1) blockade on cytokine synthesis: II. IL-1 receptor antagonist inhibits lipopolysaccharide-induced cytokine synthesis by human monocytes. Blood. 1992 May 01; 79(9):2364-9.
Score: 0.016
-
Dinarello CA. Cytokines: agents provocateurs in hemodialysis? Kidney Int. 1992 Mar; 41(3):683-94.
Score: 0.016
-
Feingold KR, Doerrler W, Dinarello CA, Fiers W, Grunfeld C. Stimulation of lipolysis in cultured fat cells by tumor necrosis factor, interleukin-1, and the interferons is blocked by inhibition of prostaglandin synthesis. Endocrinology. 1992 Jan; 130(1):10-6.
Score: 0.016
-
Bai X, Ovrutsky AR, Kartalija M, Chmura K, Kamali A, Honda JR, Oberley-Deegan RE, Dinarello CA, Crapo JD, Chang LY, Chan ED. IL-32 expression in the airway epithelial cells of patients with Mycobacterium avium complex lung disease. Int Immunol. 2011 Nov; 23(11):679-91.
Score: 0.015
-
Grunfeld C, Dinarello CA, Feingold KR. Tumor necrosis factor-alpha, interleukin-1, and interferon alpha stimulate triglyceride synthesis in HepG2 cells. Metabolism. 1991 Sep; 40(9):894-8.
Score: 0.015
-
McNamee EN, Masterson JC, Jedlicka P, McManus M, Grenz A, Collins CB, Nold MF, Nold-Petry C, Bufler P, Dinarello CA, Rivera-Nieves J. Interleukin 37 expression protects mice from colitis. Proc Natl Acad Sci U S A. 2011 Oct 04; 108(40):16711-6.
Score: 0.015
-
Moschen AR, Fritz T, Clouston AD, Rebhan I, Bauhofer O, Barrie HD, Powell EE, Kim SH, Dinarello CA, Bartenschlager R, Jonsson JR, Tilg H. Interleukin-32: a new proinflammatory cytokine involved in hepatitis C virus-related liver inflammation and fibrosis. Hepatology. 2011 Jun; 53(6):1819-29.
Score: 0.015
-
Ghezzi P, Dinarello CA, Bianchi M, Rosandich ME, Repine JE, White CW. Hypoxia increases production of interleukin-1 and tumor necrosis factor by human mononuclear cells. Cytokine. 1991 May; 3(3):189-94.
Score: 0.015
-
Feingold KR, Soued M, Adi S, Staprans I, Neese R, Shigenaga J, Doerrler W, Moser A, Dinarello CA, Grunfeld C. Effect of interleukin-1 on lipid metabolism in the rat. Similarities to and differences from tumor necrosis factor. Arterioscler Thromb. 1991 May-Jun; 11(3):495-500.
Score: 0.015
-
Wakabayashi G, Gelfand JA, Burke JF, Thompson RC, Dinarello CA. A specific receptor antagonist for interleukin 1 prevents Escherichia coli-induced shock in rabbits. FASEB J. 1991 Mar 01; 5(3):338-43.
Score: 0.015
-
Kamari Y, Shaish A, Vax E, Shemesh S, Kandel-Kfir M, Arbel Y, Olteanu S, Barshack I, Dotan S, Voronov E, Dinarello CA, Apte RN, Harats D. Lack of interleukin-1a or interleukin-1ß inhibits transformation of steatosis to steatohepatitis and liver fibrosis in hypercholesterolemic mice. J Hepatol. 2011 Nov; 55(5):1086-94.
Score: 0.015
-
Endres S, Fülle HJ, Sinha B, Stoll D, Dinarello CA, Gerzer R, Weber PC. Cyclic nucleotides differentially regulate the synthesis of tumour necrosis factor-alpha and interleukin-1 beta by human mononuclear cells. Immunology. 1991 Jan; 72(1):56-60.
Score: 0.015
-
Morin M, Schindler R, Wakabayashi G, Daumy G, Dinarello CA, Gelfand JA. Picogram concentrations of endotoxin stimulate synthesis of IL-1 beta and TNF alpha by human peripheral blood mononuclear cells exposed to recombinant human C5a. Eur Cytokine Netw. 1991 Jan-Feb; 2(1):27-30.
Score: 0.015
-
Endres S, Meydani SN, Dinarello CA. Effects of omega 3 fatty acid supplements on ex vivo synthesis of cytokines in human volunteers. Comparison with oral aspirin and ibuprofen. World Rev Nutr Diet. 1991; 66:401-6.
Score: 0.015
-
Bianchi M, Mantovani A, Erroi A, Dinarello CA, Ghezzi P. Ambroxol inhibits interleukin 1 and tumor necrosis factor production in human mononuclear cells. Agents Actions. 1990 Nov; 31(3-4):275-9.
Score: 0.014
-
Numerof RP, Kotik AN, Dinarello CA, Mier JW. Pro-interleukin-1 beta production by a subpopulation of human T cells, but not NK cells, in response to interleukin-2. Cell Immunol. 1990 Oct 01; 130(1):118-28.
Score: 0.014
-
Grunfeld C, Soued M, Adi S, Moser AH, Dinarello CA, Feingold KR. Evidence for two classes of cytokines that stimulate hepatic lipogenesis: relationships among tumor necrosis factor, interleukin-1 and interferon-alpha. Endocrinology. 1990 Jul; 127(1):46-54.
Score: 0.014
-
Munoz C, Endres S, van der Meer J, Schlesinger L, Arevalo M, Dinarello C. Interleukin-1 beta in human colostrum. Res Immunol. 1990 Jul-Aug; 141(6):505-13.
Score: 0.014
-
Molina JM, Scadden DT, Amirault C, Woon A, Vannier E, Dinarello CA, Groopman JE. Human immunodeficiency virus does not induce interleukin-1, interleukin-6, or tumor necrosis factor in mononuclear cells. J Virol. 1990 Jun; 64(6):2901-6.
Score: 0.014
-
Schindler R, Dinarello CA. Ultrafiltration to remove endotoxins and other cytokine-inducing materials from tissue culture media and parenteral fluids. Biotechniques. 1990 Apr; 8(4):408-13.
Score: 0.014
-
Schindler R, Ghezzi P, Dinarello CA. IL-1 induces IL-1. IV. IFN-gamma suppresses IL-1 but not lipopolysaccharide-induced transcription of IL-1. J Immunol. 1990 Mar 15; 144(6):2216-22.
Score: 0.014
-
Dinarello CA, Endres S, Meydani SN, Meydani M, Hellerstein MK. Interleukin-1, anorexia, and dietary fatty acids. Ann N Y Acad Sci. 1990; 587:332-8.
Score: 0.014
-
Wang M, Tan J, Wang Y, Meldrum KK, Dinarello CA, Meldrum DR. IL-18 binding protein-expressing mesenchymal stem cells improve myocardial protection after ischemia or infarction. Proc Natl Acad Sci U S A. 2009 Oct 13; 106(41):17499-504.
Score: 0.013
-
Molina JM, Scadden DT, Byrn R, Dinarello CA, Groopman JE. Production of tumor necrosis factor alpha and interleukin 1 beta by monocytic cells infected with human immunodeficiency virus. J Clin Invest. 1989 Sep; 84(3):733-7.
Score: 0.013
-
Kwiatkowski D, Cannon JG, Manogue KR, Cerami A, Dinarello CA, Greenwood BM. Tumour necrosis factor production in Falciparum malaria and its association with schizont rupture. Clin Exp Immunol. 1989 Sep; 77(3):361-6.
Score: 0.013
-
Kliger Y, Levy O, Oren A, Ashkenazy H, Tiran Z, Novik A, Rosenberg A, Amir A, Wool A, Toporik A, Schreiber E, Eshel D, Levine Z, Cohen Y, Nold-Petry C, Dinarello CA, Borukhov I. Peptides modulating conformational changes in secreted chaperones: from in silico design to preclinical proof of concept. Proc Natl Acad Sci U S A. 2009 Aug 18; 106(33):13797-801.
Score: 0.013
-
Bani-Hani AH, Leslie JA, Asanuma H, Dinarello CA, Campbell MT, Meldrum DR, Zhang H, Hile K, Meldrum KK. IL-18 neutralization ameliorates obstruction-induced epithelial-mesenchymal transition and renal fibrosis. Kidney Int. 2009 Sep; 76(5):500-11.
Score: 0.013
-
Drapkin MS, Wisch JS, Gelfand JA, Cannon JG, Dinarello CA. Plasmapheresis for fulminant meningococcemia. Pediatr Infect Dis J. 1989 Jun; 8(6):399-400.
Score: 0.013
-
Endres S, van der Meer JW, Dinarello CA. [Cytokines in the pathogenesis of fever]. Internist (Berl). 1989 Jun; 30(6):358-61.
Score: 0.013
-
Flores EA, Bistrian BR, Pomposelli JJ, Dinarello CA, Blackburn GL, Istfan NW. Infusion of tumor necrosis factor/cachectin promotes muscle catabolism in the rat. A synergistic effect with interleukin 1. J Clin Invest. 1989 May; 83(5):1614-22.
Score: 0.013
-
Dinarello CA. Interleukin-1 and its biologically related cytokines. Adv Immunol. 1989; 44:153-205.
Score: 0.013
-
Tredget EE, Yu YM, Zhong S, Burini R, Okusawa S, Gelfand JA, Dinarello CA, Young VR, Burke JF. Role of interleukin 1 and tumor necrosis factor on energy metabolism in rabbits. Am J Physiol. 1988 Dec; 255(6 Pt 1):E760-8.
Score: 0.013
-
Calabrese F, Baraldo S, Bazzan E, Lunardi F, Rea F, Maestrelli P, Turato G, Lokar-Oliani K, Papi A, Zuin R, Sfriso P, Balestro E, Dinarello CA, Saetta M. IL-32, a novel proinflammatory cytokine in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2008 Nov 01; 178(9):894-901.
Score: 0.012
-
Michie HR, Spriggs DR, Manogue KR, Sherman ML, Revhaug A, O'Dwyer ST, Arthur K, Dinarello CA, Cerami A, Wolff SM, et al. Tumor necrosis factor and endotoxin induce similar metabolic responses in human beings. Surgery. 1988 Aug; 104(2):280-6.
Score: 0.012
-
Okusawa S, Yancey KB, van der Meer JW, Endres S, Lonnemann G, Hefter K, Frank MM, Burke JF, Dinarello CA, Gelfand JA. C5a stimulates secretion of tumor necrosis factor from human mononuclear cells in vitro. Comparison with secretion of interleukin 1 beta and interleukin 1 alpha. J Exp Med. 1988 Jul 01; 168(1):443-8.
Score: 0.012
-
Vlassara H, Brownlee M, Manogue KR, Dinarello CA, Pasagian A. Cachectin/TNF and IL-1 induced by glucose-modified proteins: role in normal tissue remodeling. Science. 1988 Jun 10; 240(4858):1546-8.
Score: 0.012
-
Michie HR, Manogue KR, Spriggs DR, Revhaug A, O'Dwyer S, Dinarello CA, Cerami A, Wolff SM, Wilmore DW. Detection of circulating tumor necrosis factor after endotoxin administration. N Engl J Med. 1988 Jun 09; 318(23):1481-6.
Score: 0.012
-
Ranges GE, Zlotnik A, Espevik T, Dinarello CA, Cerami A, Palladino MA. Tumor necrosis factor alpha/cachectin is a growth factor for thymocytes. Synergistic interactions with other cytokines. J Exp Med. 1988 Apr 01; 167(4):1472-8.
Score: 0.012
-
Dinarello CA. Interleukin-1. Dig Dis Sci. 1988 Mar; 33(3 Suppl):25S-35S.
Score: 0.012
-
Marcondes AM, Mhyre AJ, Stirewalt DL, Kim SH, Dinarello CA, Deeg HJ. Dysregulation of IL-32 in myelodysplastic syndrome and chronic myelomonocytic leukemia modulates apoptosis and impairs NK function. Proc Natl Acad Sci U S A. 2008 Feb 26; 105(8):2865-70.
Score: 0.012
-
Dinarello CA, Cannon JG, Wolff SM. New concepts on the pathogenesis of fever. Rev Infect Dis. 1988 Jan-Feb; 10(1):168-89.
Score: 0.012
-
Dinarello CA. Interleukin-1--its multiple biological effects and its association with hemodialysis. Blood Purif. 1988; 6(3):164-72.
Score: 0.012
-
Mandrup-Poulsen T, Bendtzen K, Dinarello CA, Nerup J. Human tumor necrosis factor potentiates human interleukin 1-mediated rat pancreatic beta-cell cytotoxicity. J Immunol. 1987 Dec 15; 139(12):4077-82.
Score: 0.012
-
Dinarello CA, Mier JW. Lymphokines. N Engl J Med. 1987 Oct 08; 317(15):940-5.
Score: 0.012
-
Lorenzo JA, Sousa SL, Alander C, Raisz LG, Dinarello CA. Comparison of the bone-resorbing activity in the supernatants from phytohemagglutinin-stimulated human peripheral blood mononuclear cells with that of cytokines through the use of an antiserum to interleukin 1. Endocrinology. 1987 Sep; 121(3):1164-70.
Score: 0.012
-
Zucali JR, Elfenbein GJ, Barth KC, Dinarello CA. Effects of human interleukin 1 and human tumor necrosis factor on human T lymphocyte colony formation. J Clin Invest. 1987 Sep; 80(3):772-7.
Score: 0.012
-
Tan ZS, Beiser AS, Vasan RS, Roubenoff R, Dinarello CA, Harris TB, Benjamin EJ, Au R, Kiel DP, Wolf PA, Seshadri S. Inflammatory markers and the risk of Alzheimer disease: the Framingham Study. Neurology. 2007 May 29; 68(22):1902-8.
Score: 0.011
-
Lachman LB, Brown DC, Dinarello CA. Growth-promoting effect of recombinant interleukin 1 and tumor necrosis factor for a human astrocytoma cell line. J Immunol. 1987 May 01; 138(9):2913-6.
Score: 0.011
-
Movat HZ, Cybulsky MI, Colditz IG, Chan MK, Dinarello CA. Acute inflammation in gram-negative infection: endotoxin, interleukin 1, tumor necrosis factor, and neutrophils. Fed Proc. 1987 Jan; 46(1):97-104.
Score: 0.011
-
Libby P, Ordovas JM, Auger KR, Robbins AH, Birinyi LK, Dinarello CA. Endotoxin and tumor necrosis factor induce interleukin-1 gene expression in adult human vascular endothelial cells. Am J Pathol. 1986 Aug; 124(2):179-85.
Score: 0.011
-
Dinarello CA, Cannon JG, Wolff SM, Bernheim HA, Beutler B, Cerami A, Figari IS, Palladino MA, O'Connor JV. Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1. J Exp Med. 1986 Jun 01; 163(6):1433-50.
Score: 0.011
-
Joosten LA, Netea MG, Kim SH, Yoon DY, Oppers-Walgreen B, Radstake TR, Barrera P, van de Loo FA, Dinarello CA, van den Berg WB. IL-32, a proinflammatory cytokine in rheumatoid arthritis. Proc Natl Acad Sci U S A. 2006 Feb 28; 103(9):3298-303.
Score: 0.010
-
Dinarello CA. Interleukin-1: amino acid sequences, multiple biological activities and comparison with tumor necrosis factor (cachectin). Year Immunol. 1986; 2:68-89.
Score: 0.010
-
Clarke JH, Cha JY, Walsh MD, Gamboni-Robertson F, Banerjee A, Reznikov LL, Dinarello CA, Harken AH, McCarter MD. Melanoma inhibits macrophage activation by suppressing toll-like receptor 4 signaling. J Am Coll Surg. 2005 Sep; 201(3):418-25.
Score: 0.010
-
Jones-Carson J, Fantuzzi G, Siegmund B, Dinarello C, Tracey KJ, Wang H, Fang FC, Vazquez-Torres A. Suppressor alphabeta T lymphocytes control innate resistance to endotoxic shock. J Infect Dis. 2005 Sep 15; 192(6):1039-46.
Score: 0.010
-
Sennello JA, Fayad R, Morris AM, Eckel RH, Asilmaz E, Montez J, Friedman JM, Dinarello CA, Fantuzzi G. Regulation of T cell-mediated hepatic inflammation by adiponectin and leptin. Endocrinology. 2005 May; 146(5):2157-64.
Score: 0.010
-
Taube C, Nick JA, Siegmund B, Duez C, Takeda K, Rha YH, Park JW, Joetham A, Poch K, Dakhama A, Dinarello CA, Gelfand EW. Inhibition of early airway neutrophilia does not affect development of airway hyperresponsiveness. Am J Respir Cell Mol Biol. 2004 Jun; 30(6):837-43.
Score: 0.009
-
Stuyt RJ, Netea MG, Geijtenbeek TB, Kullberg BJ, Dinarello CA, van der Meer JW. Selective regulation of intercellular adhesion molecule-1 expression by interleukin-18 and interleukin-12 on human monocytes. Immunology. 2003 Nov; 110(3):329-34.
Score: 0.009
-
Roubenoff R, Parise H, Payette HA, Abad LW, D'Agostino R, Jacques PF, Wilson PW, Dinarello CA, Harris TB. Cytokines, insulin-like growth factor 1, sarcopenia, and mortality in very old community-dwelling men and women: the Framingham Heart Study. Am J Med. 2003 Oct 15; 115(6):429-35.
Score: 0.009
-
Vasan RS, Sullivan LM, Roubenoff R, Dinarello CA, Harris T, Benjamin EJ, Sawyer DB, Levy D, Wilson PW, D'Agostino RB. Inflammatory markers and risk of heart failure in elderly subjects without prior myocardial infarction: the Framingham Heart Study. Circulation. 2003 Mar 25; 107(11):1486-91.
Score: 0.008
-
Voronov E, Shouval DS, Krelin Y, Cagnano E, Benharroch D, Iwakura Y, Dinarello CA, Apte RN. IL-1 is required for tumor invasiveness and angiogenesis. Proc Natl Acad Sci U S A. 2003 Mar 04; 100(5):2645-50.
Score: 0.008
-
Banda NK, Vondracek A, Kraus D, Dinarello CA, Kim SH, Bendele A, Senaldi G, Arend WP. Mechanisms of inhibition of collagen-induced arthritis by murine IL-18 binding protein. J Immunol. 2003 Feb 15; 170(4):2100-5.
Score: 0.008
-
Raeburn CD, Dinarello CA, Zimmerman MA, Calkins CM, Pomerantz BJ, McIntyre RC, Harken AH, Meng X. Neutralization of IL-18 attenuates lipopolysaccharide-induced myocardial dysfunction. Am J Physiol Heart Circ Physiol. 2002 Aug; 283(2):H650-7.
Score: 0.008
-
Stuyt RJ, Netea MG, Verschueren I, Fantuzzi G, Dinarello CA, Van Der Meer JW, Kullberg BJ. Role of interleukin-18 in host defense against disseminated Candida albicans infection. Infect Immun. 2002 Jun; 70(6):3284-6.
Score: 0.008
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Netea MG, Kullberg BJ, Galama JM, Stalenhoef AF, Dinarello CA, Van der Meer JW. Non-LPS components of Chlamydia pneumoniae stimulate cytokine production through Toll-like receptor 2-dependent pathways. Eur J Immunol. 2002 04; 32(4):1188-95.
Score: 0.008
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Leoni F, Zaliani A, Bertolini G, Porro G, Pagani P, Pozzi P, Donà G, Fossati G, Sozzani S, Azam T, Bufler P, Fantuzzi G, Goncharov I, Kim SH, Pomerantz BJ, Reznikov LL, Siegmund B, Dinarello CA, Mascagni P. The antitumor histone deacetylase inhibitor suberoylanilide hydroxamic acid exhibits antiinflammatory properties via suppression of cytokines. Proc Natl Acad Sci U S A. 2002 Mar 05; 99(5):2995-3000.
Score: 0.008
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Schultz MJ, Rijneveld AW, Florquin S, Edwards CK, Dinarello CA, van der Poll T. Role of interleukin-1 in the pulmonary immune response during Pseudomonas aeruginosa pneumonia. Am J Physiol Lung Cell Mol Physiol. 2002 Feb; 282(2):L285-90.
Score: 0.008
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Plater-Zyberk C, Joosten LA, Helsen MM, Sattonnet-Roche P, Siegfried C, Alouani S, van De Loo FA, Graber P, Aloni S, Cirillo R, Lubberts E, Dinarello CA, van Den Berg WB, Chvatchko Y. Therapeutic effect of neutralizing endogenous IL-18 activity in the collagen-induced model of arthritis. J Clin Invest. 2001 Dec; 108(12):1825-32.
Score: 0.008
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Mordue DG, Monroy F, La Regina M, Dinarello CA, Sibley LD. Acute toxoplasmosis leads to lethal overproduction of Th1 cytokines. J Immunol. 2001 Oct 15; 167(8):4574-84.
Score: 0.008
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Hong TP, Andersen NA, Nielsen K, Karlsen AE, Fantuzzi G, Eizirik DL, Dinarello CA, Mandrup-Poulsen T. Interleukin-18 mRNA, but not interleukin-18 receptor mRNA, is constitutively expressed in islet beta-cells and up-regulated by interferon-gamma. Eur Cytokine Netw. 2000 Jun; 11(2):193-205.
Score: 0.007
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Sheridan BC, Dinarello CA, Meldrum DR, Fullerton DA, Selzman CH, McIntyre RC. Interleukin-11 attenuates pulmonary inflammation and vasomotor dysfunction in endotoxin-induced lung injury. Am J Physiol. 1999 11; 277(5):L861-7.
Score: 0.007
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Biasucci LM, Liuzzo G, Fantuzzi G, Caligiuri G, Rebuzzi AG, Ginnetti F, Dinarello CA, Maseri A. Increasing levels of interleukin (IL)-1Ra and IL-6 during the first 2 days of hospitalization in unstable angina are associated with increased risk of in-hospital coronary events. Circulation. 1999 Apr 27; 99(16):2079-84.
Score: 0.006
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Freeman LM, Rush JE, Kehayias JJ, Ross JN, Meydani SN, Brown DJ, Dolnikowski GG, Marmor BN, White ME, Dinarello CA, Roubenoff R. Nutritional alterations and the effect of fish oil supplementation in dogs with heart failure. J Vet Intern Med. 1998 Nov-Dec; 12(6):440-8.
Score: 0.006
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Kaplanski G, Fabrigoule M, Boulay V, Dinarello CA, Bongrand P, Kaplanski S, Farnarier C. Thrombin induces endothelial type II activation in vitro: IL-1 and TNF-alpha-independent IL-8 secretion and E-selectin expression. J Immunol. 1997 Jun 01; 158(11):5435-41.
Score: 0.006
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Alheim K, Chai Z, Fantuzzi G, Hasanvan H, Malinowsky D, Di Santo E, Ghezzi P, Dinarello CA, Bartfai T. Hyperresponsive febrile reactions to interleukin (IL) 1alpha and IL-1beta, and altered brain cytokine mRNA and serum cytokine levels, in IL-1beta-deficient mice. Proc Natl Acad Sci U S A. 1997 Mar 18; 94(6):2681-6.
Score: 0.006
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Torcia M, Lucibello M, Vannier E, Fabiani S, Miliani A, Guidi G, Spada O, Dower SK, Sims JE, Shaw AR, Dinarello CA, Garaci E, Cozzolino F. Modulation of osteoclast-activating factor activity of multiple myeloma bone marrow cells by different interleukin-1 inhibitors. Exp Hematol. 1996 Jul; 24(8):868-74.
Score: 0.005
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Granowitz EV, Saget BM, Wang MZ, Dinarello CA, Skolnik PR. Interleukin 1 induces HIV-1 expression in chronically infected U1 cells: blockade by interleukin 1 receptor antagonist and tumor necrosis factor binding protein type 1. Mol Med. 1995 Sep; 1(6):667-77.
Score: 0.005
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Roubenoff R, Roubenoff RA, Selhub J, Nadeau MR, Cannon JG, Freeman LM, Dinarello CA, Rosenberg IH. Abnormal vitamin B6 status in rheumatoid cachexia. Association with spontaneous tumor necrosis factor alpha production and markers of inflammation. Arthritis Rheum. 1995 Jan; 38(1):105-9.
Score: 0.005
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Mandrup-Poulsen T, Wogensen LD, Jensen M, Svensson P, Nilsson P, Emdal T, Mølvig J, Dinarello CA, Nerup J. Circulating interleukin-1 receptor antagonist concentrations are increased in adult patients with thermal injury. Crit Care Med. 1995 Jan; 23(1):26-33.
Score: 0.005
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Santos AA, Rodrick ML, Jacobs DO, Dinarello CA, Wolff SM, Mannick JA, Wilmore DW. Does the route of feeding modify the inflammatory response? Ann Surg. 1994 Aug; 220(2):155-63.
Score: 0.005
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Erroi A, Fantuzzi G, Mengozzi M, Sironi M, Orencole SF, Clark BD, Dinarello CA, Isetta A, Gnocchi P, Giovarelli M, et al. Differential regulation of cytokine production in lipopolysaccharide tolerance in mice. Infect Immun. 1993 Oct; 61(10):4356-9.
Score: 0.004
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Meydani SN, Lichtenstein AH, Cornwall S, Meydani M, Goldin BR, Rasmussen H, Dinarello CA, Schaefer EJ. Immunologic effects of national cholesterol education panel step-2 diets with and without fish-derived N-3 fatty acid enrichment. J Clin Invest. 1993 Jul; 92(1):105-13.
Score: 0.004
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Santos AA, Scheltinga MR, Lynch E, Brown EF, Lawton P, Chambers E, Browning J, Dinarello CA, Wolff SM, Wilmore DW. Elaboration of interleukin 1-receptor antagonist is not attenuated by glucocorticoids after endotoxemia. Arch Surg. 1993 Feb; 128(2):138-43; discussion 143-4.
Score: 0.004
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Feingold KR, Staprans I, Memon RA, Moser AH, Shigenaga JK, Doerrler W, Dinarello CA, Grunfeld C. Endotoxin rapidly induces changes in lipid metabolism that produce hypertriglyceridemia: low doses stimulate hepatic triglyceride production while high doses inhibit clearance. J Lipid Res. 1992 Dec; 33(12):1765-76.
Score: 0.004
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Avraham H, Vannier E, Cowley S, Jiang SX, Chi S, Dinarello CA, Zsebo KM, Groopman JE. Effects of the stem cell factor, c-kit ligand, on human megakaryocytic cells. Blood. 1992 Jan 15; 79(2):365-71.
Score: 0.004
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Houba V, Berger FM, Dinarello CA, Johnson AG, Le J, Mauël J, Van der Meer JW, Philippeaux MM, Vilcek J, Vogels MT. Protodyne: an immunostimulatory protein component, prepared from gram-positive Bacillus subtilis. Dev Biol Stand. 1992; 77:121-8.
Score: 0.004
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Grunfeld C, Soued M, Adi S, Moser AH, Fiers W, Dinarello CA, Feingold KR. Interleukin 4 inhibits stimulation of hepatic lipogenesis by tumor necrosis factor, interleukin 1, and interleukin 6 but not by interferon-alpha. Cancer Res. 1991 Jun 01; 51(11):2803-7.
Score: 0.004
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Meydani SN, Endres S, Woods MM, Goldin BR, Soo C, Morrill-Labrode A, Dinarello CA, Gorbach SL. Oral (n-3) fatty acid supplementation suppresses cytokine production and lymphocyte proliferation: comparison between young and older women. J Nutr. 1991 Apr; 121(4):547-55.
Score: 0.004
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Miller LG, Galpern WR, Dunlap K, Dinarello CA, Turner TJ. Interleukin-1 augments gamma-aminobutyric acidA receptor function in brain. Mol Pharmacol. 1991 Feb; 39(2):105-8.
Score: 0.004
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Meydani SN, Endres S, Woods MM, Goldin BR, Soo C, Morrill-Labrode A, Dinarello CA, Gorbach SL. Effect of oral n-3 fatty acid supplementation on the immune response of young and older women. Adv Prostaglandin Thromboxane Leukot Res. 1991; 21A:245-8.
Score: 0.004
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Molina JM, Schindler R, Ferriani R, Sakaguchi M, Vannier E, Dinarello CA, Groopman JE. Production of cytokines by peripheral blood monocytes/macrophages infected with human immunodeficiency virus type 1 (HIV-1). J Infect Dis. 1990 May; 161(5):888-93.
Score: 0.003
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White CW, Ghezzi P, McMahon S, Dinarello CA, Repine JE. Cytokines increase rat lung antioxidant enzymes during exposure to hyperoxia. J Appl Physiol (1985). 1989 Feb; 66(2):1003-7.
Score: 0.003
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Kaplan E, Dinarello CA, Gelfand JA. Interleukin-1 and the response to injury. Immunol Res. 1989; 8(2):118-29.
Score: 0.003
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Haak-Frendscho M, Dinarello C, Kaplan AP. Recombinant human interleukin-1 beta causes histamine release from human basophils. J Allergy Clin Immunol. 1988 Aug; 82(2):218-23.
Score: 0.003
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Tocco-Bradley R, Georgieff M, Jones CT, Moldawer LL, Dinarello CA, Blackburn GL, Bistrian BR. Changes in energy expenditure and fat metabolism in rats infused with interleukin-1. Eur J Clin Invest. 1987 Dec; 17(6):504-10.
Score: 0.003
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Lonnemann G, van der Meer JW, Cannon JG, Dinarello CA, Koch KM, Granolleras C, Deschodt G, Shaldon S. Induction of tumor necrosis factor during extracorporeal blood purification. N Engl J Med. 1987 Oct 08; 317(15):963-4.
Score: 0.003
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Van Damme J, De Ley M, Van Snick J, Dinarello CA, Billiau A. The role of interferon-beta 1 and the 26-kDa protein (interferon-beta 2) as mediators of the antiviral effect of interleukin 1 and tumor necrosis factor. J Immunol. 1987 Sep 15; 139(6):1867-72.
Score: 0.003
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Mier JW, Dinarello CA, Atkins MB, Punsal PI, Perlmutter DH. Regulation of hepatic acute phase protein synthesis by products of interleukin 2 (IL 2)-stimulated human peripheral blood mononuclear cells. J Immunol. 1987 Aug 15; 139(4):1268-72.
Score: 0.003
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Shoham S, Davenne D, Cady AB, Dinarello CA, Krueger JM. Recombinant tumor necrosis factor and interleukin 1 enhance slow-wave sleep. Am J Physiol. 1987 Jul; 253(1 Pt 2):R142-9.
Score: 0.003
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White CW, Ghezzi P, Dinarello CA, Caldwell SA, McMurtry IF, Repine JE. Recombinant tumor necrosis factor/cachectin and interleukin 1 pretreatment decreases lung oxidized glutathione accumulation, lung injury, and mortality in rats exposed to hyperoxia. J Clin Invest. 1987 Jun; 79(6):1868-73.
Score: 0.003
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Perlmutter DH, Dinarello CA, Punsal PI, Colten HR. Cachectin/tumor necrosis factor regulates hepatic acute-phase gene expression. J Clin Invest. 1986 Nov; 78(5):1349-54.
Score: 0.003
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Lachman LB, Dinarello CA, Llansa ND, Fidler IJ. Natural and recombinant human interleukin 1-beta is cytotoxic for human melanoma cells. J Immunol. 1986 Apr 15; 136(8):3098-102.
Score: 0.003
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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