Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution

Contact Us
If you have any questions or feedback please contact us.

Connection

Charles Dinarello to Lymphocyte Activation

This is a "connection" page, showing publications Charles Dinarello has written about Lymphocyte Activation.

 
Connection Strength
 
 
 
1.016
 
  1. Chernoff AE, Granowitz EV, Shapiro L, Vannier E, Lonnemann G, Angel JB, Kennedy JS, Rabson AR, Wolff SM, Dinarello CA. A randomized, controlled trial of IL-10 in humans. Inhibition of inflammatory cytokine production and immune responses. J Immunol. 1995 May 15; 154(10):5492-9.
    View in: PubMed
    Score: 0.084
  2. Rasmussen TA, Schmeltz Søgaard O, Brinkmann C, Wightman F, Lewin SR, Melchjorsen J, Dinarello C, Østergaard L, Tolstrup M. Comparison of HDAC inhibitors in clinical development: effect on HIV production in latently infected cells and T-cell activation. Hum Vaccin Immunother. 2013 May; 9(5):993-1001.
    View in: PubMed
    Score: 0.072
  3. Cannon JG, Tatro JB, Reichlin S, Dinarello CA. Alpha melanocyte stimulating hormone inhibits immunostimulatory and inflammatory actions of interleukin 1. J Immunol. 1986 Oct 01; 137(7):2232-6.
    View in: PubMed
    Score: 0.046
  4. Lipsky PE, Thompson PA, Rosenwasser LJ, Dinarello CA. The role of interleukin 1 in human B cell activation: inhibition of B cell proliferation and the generation of immunoglobulin-secreting cells by an antibody against human leukocytic pyrogen. J Immunol. 1983 Jun; 130(6):2708-14.
    View in: PubMed
    Score: 0.037
  5. Rosenwasser LJ, Dinarello CA. Ability of human leukocytic pyrogen to enhance phytohemagglutinin induced murine thymocyte proliferation. Cell Immunol. 1981 Sep 01; 63(1):134-42.
    View in: PubMed
    Score: 0.033
  6. Kouwenberg M, Pulskens WPC, Diepeveen L, Bakker-van Bebber M, Dinarello CA, Netea MG, Hilbrands LB, van der Vlag J. Reduced CXCL1 production by endogenous IL-37 expressing dendritic cells does not affect T cell activation. PLoS One. 2021; 16(5):e0251809.
    View in: PubMed
    Score: 0.032
  7. Wade MF, Collins MK, Richards D, Mack DG, Martin AK, Dinarello CA, Fontenot AP, McKee AS. TLR9 and IL-1R1 Promote Mobilization of Pulmonary Dendritic Cells during Beryllium Sensitization. J Immunol. 2018 10 15; 201(8):2232-2243.
    View in: PubMed
    Score: 0.027
  8. Yoon DY, Dinarello CA. Antibodies to domains II and III of the IL-1 receptor accessory protein inhibit IL-1 beta activity but not binding: regulation of IL-1 responses is via type I receptor, not the accessory protein. J Immunol. 1998 Apr 01; 160(7):3170-9.
    View in: PubMed
    Score: 0.026
  9. Fantuzzi G, Puren AJ, Harding MW, Livingston DJ, Dinarello CA. Interleukin-18 regulation of interferon gamma production and cell proliferation as shown in interleukin-1beta-converting enzyme (caspase-1)-deficient mice. Blood. 1998 Mar 15; 91(6):2118-25.
    View in: PubMed
    Score: 0.026
  10. Shapiro L, Dinarello CA. Hyperosmotic stress as a stimulant for proinflammatory cytokine production. Exp Cell Res. 1997 Mar 15; 231(2):354-62.
    View in: PubMed
    Score: 0.024
  11. Vannier E, de Waal Malefyt R, Salazar-Montes A, de Vries JE, Dinarello CA. Interleukin-13 (IL-13) induces IL-1 receptor antagonist gene expression and protein synthesis in peripheral blood mononuclear cells: inhibition by an IL-4 mutant protein. Blood. 1996 Apr 15; 87(8):3307-15.
    View in: PubMed
    Score: 0.022
  12. Rider P, Carmi Y, Yossef R, Guttman O, Eini H, Azam T, Dinarello CA, Lewis EC. IL-1 Receptor Antagonist Chimeric Protein: Context-Specific and Inflammation-Restricted Activation. J Immunol. 2015 Aug 15; 195(4):1705-12.
    View in: PubMed
    Score: 0.021
  13. Højen JF, Rasmussen TA, Andersen KL, Winckelmann AA, Laursen RR, Gunst JD, Møller HJ, Fujita M, Østergaard L, Søgaard OS, Dinarello CA, Tolstrup M. Interleukin-37 Expression Is Increased in Chronic HIV-1-Infected Individuals and Is Associated with Inflammation and the Size of the Total Viral Reservoir. Mol Med. 2015 Apr 14; 21:337-45.
    View in: PubMed
    Score: 0.021
  14. Tilg H, Vogel W, Dinarello CA. Interferon-alpha induces circulating tumor necrosis factor receptor p55 in humans. Blood. 1995 Jan 15; 85(2):433-5.
    View in: PubMed
    Score: 0.021
  15. Kaplanski G, Farnarier C, Kaplanski S, Porat R, Shapiro L, Bongrand P, Dinarello CA. Interleukin-1 induces interleukin-8 secretion from endothelial cells by a juxtacrine mechanism. Blood. 1994 Dec 15; 84(12):4242-8.
    View in: PubMed
    Score: 0.020
  16. Meydani SN, Lichtenstein AH, Cornwall S, Meydani M, Goldin BR, Rasmussen H, Dinarello CA, Schaefer EJ. Immunologic effects of national cholesterol education panel step-2 diets with and without fish-derived N-3 fatty acid enrichment. J Clin Invest. 1993 Jul; 92(1):105-13.
    View in: PubMed
    Score: 0.019
  17. Granowitz EV, Porat R, Mier JW, Pribble JP, Stiles DM, Bloedow DC, Catalano MA, Wolff SM, Dinarello CA. Pharmacokinetics, safety and immunomodulatory effects of human recombinant interleukin-1 receptor antagonist in healthy humans. Cytokine. 1992 Sep; 4(5):353-60.
    View in: PubMed
    Score: 0.017
  18. Dinarello CA, Cannon JG, Mancilla J, Bishai I, Lees J, Coceani F. Interleukin-6 as an endogenous pyrogen: induction of prostaglandin E2 in brain but not in peripheral blood mononuclear cells. Brain Res. 1991 Oct 25; 562(2):199-206.
    View in: PubMed
    Score: 0.016
  19. Conti P, Reale M, Barbacane RC, Panara MR, Bongrazio M, Dempsey RA, Dinarello CA. Reduced mitogen stimulation of DNA synthesis in human lymphocytes by a human recombinant interleukin-1 receptor antagonist. Immunol Lett. 1991 Apr; 28(1):19-25.
    View in: PubMed
    Score: 0.016
  20. Meydani SN, Endres S, Woods MM, Goldin BR, Soo C, Morrill-Labrode A, Dinarello CA, Gorbach SL. Effect of oral n-3 fatty acid supplementation on the immune response of young and older women. Adv Prostaglandin Thromboxane Leukot Res. 1991; 21A:245-8.
    View in: PubMed
    Score: 0.016
  21. Endres S, Cannon JG, Ghorbani R, Dempsey RA, Sisson SD, Lonnemann G, Van der Meer JW, Wolff SM, Dinarello CA. In vitro production of IL 1 beta, IL 1 alpha, TNF and IL2 in healthy subjects: distribution, effect of cyclooxygenase inhibition and evidence of independent gene regulation. Eur J Immunol. 1989 Dec; 19(12):2327-33.
    View in: PubMed
    Score: 0.014
  22. Tsoukas CD, Watry D, Escobar SS, Provvedini DM, Dinarello CA, Hustmyer FG, Manolagas SC. Inhibition of interleukin-1 production by 1,25-dihydroxyvitamin D3. J Clin Endocrinol Metab. 1989 Jul; 69(1):127-33.
    View in: PubMed
    Score: 0.014
  23. Dinarello CA. Interleukin-1 and its biologically related cytokines. Adv Immunol. 1989; 44:153-205.
    View in: PubMed
    Score: 0.014
  24. Dinarello CA, Savage N. Interleukin-1 and its receptor. Crit Rev Immunol. 1989; 9(1):1-20.
    View in: PubMed
    Score: 0.014
  25. Rosoff PM, Savage N, Dinarello CA. Interleukin-1 stimulates diacylglycerol production in T lymphocytes by a novel mechanism. Cell. 1988 Jul 01; 54(1):73-81.
    View in: PubMed
    Score: 0.013
  26. Reddy P, Sun Y, Toubai T, Duran-Struuck R, Clouthier SG, Weisiger E, Maeda Y, Tawara I, Krijanovski O, Gatza E, Liu C, Malter C, Mascagni P, Dinarello CA, Ferrara JL. Histone deacetylase inhibition modulates indoleamine 2,3-dioxygenase-dependent DC functions and regulates experimental graft-versus-host disease in mice. J Clin Invest. 2008 Jul; 118(7):2562-73.
    View in: PubMed
    Score: 0.013
  27. Ghezzi P, Dinarello CA. IL-1 induces IL-1. III. Specific inhibition of IL-1 production by IFN-gamma. J Immunol. 1988 Jun 15; 140(12):4238-44.
    View in: PubMed
    Score: 0.013
  28. Muñoz CG, Keusch GT, Dinarello CA. A new micromethod for determination of interleukin-1 production from frozen human blood mononuclear cells. J Immunol Methods. 1987 May 04; 99(1):123-7.
    View in: PubMed
    Score: 0.012
  29. Gauldie J, Sauder DN, McAdam KP, Dinarello CA. Purified interleukin-1 (IL-1) from human monocytes stimulates acute-phase protein synthesis by rodent hepatocytes in vitro. Immunology. 1987 Feb; 60(2):203-7.
    View in: PubMed
    Score: 0.012
  30. Schnyder J, Payne T, Dinarello CA. Human monocyte or recombinant interleukin 1's are specific for the secretion of a metalloproteinase from chondrocytes. J Immunol. 1987 Jan 15; 138(2):496-503.
    View in: PubMed
    Score: 0.012
  31. Dinarello CA. Interleukin-1: multiple biological properties and mechanisms of action. Adv Prostaglandin Thromboxane Leukot Res. 1987; 17B:900-4.
    View in: PubMed
    Score: 0.012
  32. Hunninghake GW, Glazier AJ, Monick MM, Dinarello CA. Interleukin-1 is a chemotactic factor for human T-lymphocytes. Am Rev Respir Dis. 1987 Jan; 135(1):66-71.
    View in: PubMed
    Score: 0.012
  33. Lonnemann G, Bingel M, Koch KM, Shaldon S, Dinarello CA. Plasma interleukin-1 activity in humans undergoing hemodialysis with regenerated cellulosic membranes. Lymphokine Res. 1987; 6(2):63-70.
    View in: PubMed
    Score: 0.012
  34. Dinarello CA. The multiple biological properties of interleukin-1 influencing immunocompetent cells. Adv Exp Med Biol. 1987; 213:103-14.
    View in: PubMed
    Score: 0.012
  35. Dinarello CA. Multiple biological properties of recombinant human interleukin 1 (beta). Immunobiology. 1986 Sep; 172(3-5):301-15.
    View in: PubMed
    Score: 0.012
  36. Dinarello CA, Cannon JG, Mier JW, Bernheim HA, LoPreste G, Lynn DL, Love RN, Webb AC, Auron PE, Reuben RC, et al. Multiple biological activities of human recombinant interleukin 1. J Clin Invest. 1986 Jun; 77(6):1734-9.
    View in: PubMed
    Score: 0.011
  37. Dayer JM, de Rochemonteix B, Burrus B, Demczuk S, Dinarello CA. Human recombinant interleukin 1 stimulates collagenase and prostaglandin E2 production by human synovial cells. J Clin Invest. 1986 Feb; 77(2):645-8.
    View in: PubMed
    Score: 0.011
  38. Dinarello CA. Interleukin-1: amino acid sequences, multiple biological activities and comparison with tumor necrosis factor (cachectin). Year Immunol. 1986; 2:68-89.
    View in: PubMed
    Score: 0.011
  39. Williams JM, Deloria D, Hansen JA, Dinarello CA, Loertscher R, Shapiro HM, Strom TB. The events of primary T cell activation can be staged by use of Sepharose-bound anti-T3 (64.1) monoclonal antibody and purified interleukin 1. J Immunol. 1985 Oct; 135(4):2249-55.
    View in: PubMed
    Score: 0.011
  40. Mazodier K, Marin V, Novick D, Farnarier C, Robitail S, Schleinitz N, Veit V, Paul P, Rubinstein M, Dinarello CA, Harlé JR, Kaplanski G. Severe imbalance of IL-18/IL-18BP in patients with secondary hemophagocytic syndrome. Blood. 2005 Nov 15; 106(10):3483-9.
    View in: PubMed
    Score: 0.011
  41. Peters M, Butler JL, Margolick JB, Gerrard TL, Dinarello CA, Fauci AS. Synergy of helper factors in the differentiation of in vivo-preactivated antigen-specific human B cells. Cell Immunol. 1985 Mar; 91(1):33-42.
    View in: PubMed
    Score: 0.010
  42. Chu ET, Lareau M, Rosenwasser LJ, Dinarello CA, Geha RS. Antigen presentation by EBV-B cells to resting and activated T cells: role of interleukin 1. J Immunol. 1985 Mar; 134(3):1676-81.
    View in: PubMed
    Score: 0.010
  43. Libby P, Wyler DJ, Janicka MW, Dinarello CA. Differential effects of human interleukin-1 on growth of human fibroblasts and vascular smooth muscle cells. Arteriosclerosis. 1985 Mar-Apr; 5(2):186-91.
    View in: PubMed
    Score: 0.010
  44. Sennello JA, Fayad R, Morris AM, Eckel RH, Asilmaz E, Montez J, Friedman JM, Dinarello CA, Fantuzzi G. Regulation of T cell-mediated hepatic inflammation by adiponectin and leptin. Endocrinology. 2005 May; 146(5):2157-64.
    View in: PubMed
    Score: 0.010
  45. Dinarello CA, Clowes GH, Gordon AH, Saravis CA, Wolff SM. Cleavage of human interleukin 1: isolation of a peptide fragment from plasma of febrile humans and activated monocytes. J Immunol. 1984 Sep; 133(3):1332-8.
    View in: PubMed
    Score: 0.010
  46. Chu E, Rosenwasser LJ, Dinarello CA, Lareau M, Geha RS. Role of interleukin 1 in antigen-specific T cell proliferation. J Immunol. 1984 Mar; 132(3):1311-6.
    View in: PubMed
    Score: 0.010
  47. Bossù P, Neumann D, Del Giudice E, Ciaramella A, Gloaguen I, Fantuzzi G, Dinarello CA, Di Carlo E, Musiani P, Meroni PL, Caselli G, Ruggiero P, Boraschi D. IL-18 cDNA vaccination protects mice from spontaneous lupus-like autoimmune disease. Proc Natl Acad Sci U S A. 2003 Nov 25; 100(24):14181-6.
    View in: PubMed
    Score: 0.009
  48. Falkoff RJ, Muraguchi A, Hong JX, Butler JL, Dinarello CA, Fauci AS. The effects of interleukin 1 on human B cell activation and proliferation. J Immunol. 1983 Aug; 131(2):801-5.
    View in: PubMed
    Score: 0.009
  49. Banda NK, Vondracek A, Kraus D, Dinarello CA, Kim SH, Bendele A, Senaldi G, Arend WP. Mechanisms of inhibition of collagen-induced arthritis by murine IL-18 binding protein. J Immunol. 2003 Feb 15; 170(4):2100-5.
    View in: PubMed
    Score: 0.009
  50. Dinarello CA, Marnoy SO, Rosenwasser LJ. Role of arachidonate metabolism in the immunoregulatory function of human leukocytic pyrogen/lymphocyte-activating factor/interleukin 1. J Immunol. 1983 Feb; 130(2):890-5.
    View in: PubMed
    Score: 0.009
  51. Rosenwasser LJ, Dinarello CA, Rosenthal AS. Adherent cell function in murine T-lymphocyte antigen recognition. IV. Enhancement of murine T-cell antigen recognition by human leukocytic pyrogen. J Exp Med. 1979 Sep 19; 150(3):709-14.
    View in: PubMed
    Score: 0.007
  52. Dinarello CA, Chusid MJ, Fauci AS, Gallin JI, Dale DC, Wolff SM. Effect of prophylactic colchicine therapy on leukocyte function in patients with familial Mediterranean fever. Arthritis Rheum. 1976 May-Jun; 19(3):618-22.
    View in: PubMed
    Score: 0.006
  53. Manetti R, Barak V, Piccinni MP, Sampognaro S, Parronchi P, Maggi E, Dinarello CA, Romagnani S. Interleukin-1 favours the in vitro development of type 2 T helper (Th2) human T-cell clones. Res Immunol. 1994 Feb; 145(2):93-100.
    View in: PubMed
    Score: 0.005
  54. Tilg H, Shapiro L, Atkins MB, Dinarello CA, Mier JW. Induction of circulating and erythrocyte-bound IL-8 by IL-2 immunotherapy and suppression of its in vitro production by IL-1 receptor antagonist and soluble tumor necrosis factor receptor (p75) chimera. J Immunol. 1993 Sep 15; 151(6):3299-307.
    View in: PubMed
    Score: 0.005
  55. Zumsteg U, Reimers JI, Pociot F, Mørch L, Helqvist S, Brendel M, Alejandro R, Mandrup-Poulsen T, Dinarello CA, Nerup J. Differential interleukin-1 receptor antagonism on pancreatic beta and alpha cells. Studies in rodent and human islets and in normal rats. Diabetologia. 1993 Aug; 36(8):759-66.
    View in: PubMed
    Score: 0.005
  56. Houba V, Berger FM, Dinarello CA, Johnson AG, Le J, Mauël J, Van der Meer JW, Philippeaux MM, Vilcek J, Vogels MT. Protodyne: an immunostimulatory protein component, prepared from gram-positive Bacillus subtilis. Dev Biol Stand. 1992; 77:121-8.
    View in: PubMed
    Score: 0.004
  57. Wilson CS, Ellner JJ, Dinarello CA, Keusch GT, el Kholy A. Dissociation of immunoregulatory function of blood monocytes from maturational state and expression of interleukin-1 in humans chronically infected with Schistosoma mansoni. Am J Trop Med Hyg. 1990 Mar; 42(3):234-42.
    View in: PubMed
    Score: 0.004
  58. Tagaya Y, Okada M, Sugie K, Kasahara T, Kondo N, Hamuro J, Matsushima K, Dinarello CA, Yodoi J. IL-2 receptor(p55)/Tac-inducing factor. Purification and characterization of adult T cell leukemia-derived factor. J Immunol. 1988 Apr 15; 140(8):2614-20.
    View in: PubMed
    Score: 0.003
  59. Mannie MD, Dinarello CA, Paterson PY. Interleukin 1 and myelin basic protein synergistically augment adoptive transfer activity of lymphocytes mediating experimental autoimmune encephalomyelitis in Lewis rats. J Immunol. 1987 Jun 15; 138(12):4229-35.
    View in: PubMed
    Score: 0.003
  60. Le PT, Tuck DT, Dinarello CA, Haynes BF, Singer KH. Human thymic epithelial cells produce interleukin 1. J Immunol. 1987 Apr 15; 138(8):2520-6.
    View in: PubMed
    Score: 0.003
  61. Bagby GC, Dinarello CA, Wallace P, Wagner C, Hefeneider S, McCall E. Interleukin 1 stimulates granulocyte macrophage colony-stimulating activity release by vascular endothelial cells. J Clin Invest. 1986 Nov; 78(5):1316-23.
    View in: PubMed
    Score: 0.003
  62. Lotz M, Tsoukas CD, Robinson CA, Dinarello CA, Carson DA, Vaughan JH. Basis for defective responses of rheumatoid arthritis synovial fluid lymphocytes to anti-CD3 (T3) antibodies. J Clin Invest. 1986 Sep; 78(3):713-21.
    View in: PubMed
    Score: 0.003
  63. Rosenwasser LJ, Webb AC, Clark BD, Irie S, Chang L, Dinarello CA, Gehrke L, Wolff SM, Rich A, Auron PE. Expression of biologically active human interleukin 1 subpeptides by transfected simian COS cells. Proc Natl Acad Sci U S A. 1986 Jul; 83(14):5243-6.
    View in: PubMed
    Score: 0.003
  64. Lotz M, Tsoukas CD, Fong S, Dinarello CA, Carson DA, Vaughan JH. Release of lymphokines after Epstein Barr virus infection in vitro. I. Sources of and kinetics of production of interferons and interleukins in normal humans. J Immunol. 1986 May 15; 136(10):3636-42.
    View in: PubMed
    Score: 0.003
  65. Miossec P, Dinarello CA, Ziff M. Interleukin-1 lymphocyte chemotactic activity in rheumatoid arthritis synovial fluid. Arthritis Rheum. 1986 Apr; 29(4):461-70.
    View in: PubMed
    Score: 0.003
  66. Valentine M, Lotz M, Dinarello CA, Carson DA, Vaughan JH. Lymphoblastoid B cell lines produce an interleukin-1-like activity that can be serologically distinct from macrophage interleukin-1. Lymphokine Res. 1986; 5(3):173-83.
    View in: PubMed
    Score: 0.003
  67. Hamby BA, Huggins EM, Lachman LB, Dinarello CA, Sigel MM. Fish lymphocytes respond to human IL-1. Lymphokine Res. 1986; 5(2):157-62.
    View in: PubMed
    Score: 0.003
  68. Williams JM, Dinarello CA, Rosenwasser LJ, Kelley V, Reddish M, Strom TB. Phorbol myristate acetate-protein complex mimics bioactivity of human IL-1. 1. Direct evidence that PMA temporarily enters and is released from cellular compartment during superinduction protocol. Lymphokine Res. 1985; 4(4):275-97.
    View in: PubMed
    Score: 0.003
  69. Kaye J, Gillis S, Mizel SB, Shevach EM, Malek TR, Dinarello CA, Lachman LB, Janeway CA. Growth of a cloned helper T cell line induced by a monoclonal antibody specific for the antigen receptor: interleukin 1 is required for the expression of receptors for interleukin 2. J Immunol. 1984 Sep; 133(3):1339-45.
    View in: PubMed
    Score: 0.003
  70. Falkoff RJ, Butler JL, Dinarello CA, Fauci AS. Direct effects of a monoclonal B cell differentiation factor and of purified interleukin 1 on B cell differentiation. J Immunol. 1984 Aug; 133(2):692-6.
    View in: PubMed
    Score: 0.002
  71. Sauder DN, Mounessa NL, Katz SI, Dinarello CA, Gallin JI. Chemotactic cytokines: the role of leukocytic pyrogen and epidermal cell thymocyte-activating factor in neutrophil chemotaxis. J Immunol. 1984 Feb; 132(2):828-32.
    View in: PubMed
    Score: 0.002
  72. Chedid L, Bahr GM, Modabber FZ, Dinarello CA, Wolff SM. [Demonstration of a bacterial structure in two human mediators: a sleep facilitating factor and a monokine]. C R Seances Acad Sci III. 1983; 297(4):209-12.
    View in: PubMed
    Score: 0.002
  73. Beer DJ, Dinarello CA, Rosenwasser LJ, Rocklin RE. Human monocyte-derived soluble product(s) has an accessory function in the generation of histamine- and concanavalin A-induced suppressor T cells. J Clin Invest. 1982 Aug; 70(2):393-400.
    View in: PubMed
    Score: 0.002
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

Copyright © 2026 The Regents of the University of Colorado, a body corporate. All rights reserved. (Harvard PROFILES RNS software version: 2.11.1)