 Connection
Charles Dinarello to Macrophages
This is a "connection" page, showing publications Charles Dinarello has written about Macrophages.
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Connection Strength |
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2.155 |
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Marchetti C, Swartzwelter B, Gamboni F, Neff CP, Richter K, Azam T, Carta S, Tengesdal I, Nemkov T, D'Alessandro A, Henry C, Jones GS, Goodrich SA, St Laurent JP, Jones TM, Scribner CL, Barrow RB, Altman RD, Skouras DB, Gattorno M, Grau V, Janciauskiene S, Rubartelli A, Joosten LAB, Dinarello CA. OLT1177, a ?-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation. Proc Natl Acad Sci U S A. 2018 02 13; 115(7):E1530-E1539.
Score: 0.367
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Netea MG, Nold-Petry CA, Nold MF, Joosten LA, Opitz B, van der Meer JH, van de Veerdonk FL, Ferwerda G, Heinhuis B, Devesa I, Funk CJ, Mason RJ, Kullberg BJ, Rubartelli A, van der Meer JW, Dinarello CA. Differential requirement for the activation of the inflammasome for processing and release of IL-1beta in monocytes and macrophages. Blood. 2009 Mar 05; 113(10):2324-35.
Score: 0.195
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Dos Santos JC, Heinhuis B, Gomes RS, Damen MS, Real F, Mortara RA, Keating ST, Dinarello CA, Joosten LA, Ribeiro-Dias F. Cytokines and microbicidal molecules regulated by IL-32 in THP-1-derived human macrophages infected with New World Leishmania species. PLoS Negl Trop Dis. 2017 02; 11(2):e0005413.
Score: 0.086
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Bai X, Kinney WH, Su WL, Bai A, Ovrutsky AR, Honda JR, Netea MG, Henao-Tamayo M, Ordway DJ, Dinarello CA, Chan ED. Caspase-3-independent apoptotic pathways contribute to interleukin-32?-mediated control of Mycobacterium tuberculosis infection in THP-1 cells. BMC Microbiol. 2015 Feb 21; 15:39.
Score: 0.075
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Li S, Neff CP, Barber K, Hong J, Luo Y, Azam T, Palmer BE, Fujita M, Garlanda C, Mantovani A, Kim S, Dinarello CA. Extracellular forms of IL-37 inhibit innate inflammation in vitro and in vivo but require the IL-1 family decoy receptor IL-1R8. Proc Natl Acad Sci U S A. 2015 Feb 24; 112(8):2497-502.
Score: 0.075
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Dinarello CA, Bufler P. Interleukin-37. Semin Immunol. 2013 Dec 15; 25(6):466-8.
Score: 0.069
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Wang J, Nikrad MP, Travanty EA, Zhou B, Phang T, Gao B, Alford T, Ito Y, Nahreini P, Hartshorn K, Wentworth D, Dinarello CA, Mason RJ. Innate immune response of human alveolar macrophages during influenza A infection. PLoS One. 2012; 7(3):e29879.
Score: 0.061
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Bai X, Ovrutsky AR, Kartalija M, Chmura K, Kamali A, Honda JR, Oberley-Deegan RE, Dinarello CA, Crapo JD, Chang LY, Chan ED. IL-32 expression in the airway epithelial cells of patients with Mycobacterium avium complex lung disease. Int Immunol. 2011 Nov; 23(11):679-91.
Score: 0.059
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Dinarello CA. A clinical perspective of IL-1? as the gatekeeper of inflammation. Eur J Immunol. 2011 May; 41(5):1203-17.
Score: 0.057
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Bai X, Kim SH, Azam T, McGibney MT, Huang H, Dinarello CA, Chan ED. IL-32 is a host protective cytokine against Mycobacterium tuberculosis in differentiated THP-1 human macrophages. J Immunol. 2010 Apr 01; 184(7):3830-40.
Score: 0.053
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Sharma S, Kulk N, Nold MF, Gr?f R, Kim SH, Reinhardt D, Dinarello CA, Bufler P. The IL-1 family member 7b translocates to the nucleus and down-regulates proinflammatory cytokines. J Immunol. 2008 Apr 15; 180(8):5477-82.
Score: 0.046
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Netea MG, Lewis EC, Azam T, Joosten LA, Jaekal J, Bae SY, Dinarello CA, Kim SH. Interleukin-32 induces the differentiation of monocytes into macrophage-like cells. Proc Natl Acad Sci U S A. 2008 Mar 04; 105(9):3515-20.
Score: 0.046
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Ghezzi P, Saccardo B, Villa P, Rossi V, Bianchi M, Dinarello CA. Role of interleukin-1 in the depression of liver drug metabolism by endotoxin. Infect Immun. 1986 Dec; 54(3):837-40.
Score: 0.042
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Boraschi D, Dinarello CA. IL-18 in autoimmunity: review. Eur Cytokine Netw. 2006 Dec; 17(4):224-52.
Score: 0.042
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Netea MG, Azam T, Lewis EC, Joosten LA, Wang M, Langenberg D, Meng X, Chan ED, Yoon DY, Ottenhoff T, Kim SH, Dinarello CA. Mycobacterium tuberculosis induces interleukin-32 production through a caspase- 1/IL-18/interferon-gamma-dependent mechanism. PLoS Med. 2006 Aug; 3(8):e277.
Score: 0.041
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Conti P, Cifone MG, Alesse E, Reale M, Fieschi C, Dinarello CA. In vitro enhanced thromboxane B2 release by polymorphonuclear leukocytes and macrophages after treatment with human recombinant interleukin 1. Prostaglandins. 1986 Jul; 32(1):111-5.
Score: 0.041
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Bufler P, Gamboni-Robertson F, Azam T, Kim SH, Dinarello CA. Interleukin-1 homologues IL-1F7b and IL-18 contain functional mRNA instability elements within the coding region responsive to lipopolysaccharide. Biochem J. 2004 Jul 15; 381(Pt 2):503-10.
Score: 0.036
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Lee JK, Kim SH, Lewis EC, Azam T, Reznikov LL, Dinarello CA. Differences in signaling pathways by IL-1beta and IL-18. Proc Natl Acad Sci U S A. 2004 Jun 08; 101(23):8815-20.
Score: 0.035
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Teufel LU, Netea MG, van de Veerdonk FL, Dinarello CA, Joosten LAB, Arts RJW. Opposing Effects of Interleukin-36? and Interleukin-38 on Trained Immunity. Int J Mol Sci. 2023 Jan 24; 24(3).
Score: 0.032
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Corbaz A, ten Hove T, Herren S, Graber P, Schwartsburd B, Belzer I, Harrison J, Plitz T, Kosco-Vilbois MH, Kim SH, Dinarello CA, Novick D, van Deventer S, Chvatchko Y. IL-18-binding protein expression by endothelial cells and macrophages is up-regulated during active Crohn's disease. J Immunol. 2002 Apr 01; 168(7):3608-16.
Score: 0.031
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Molteni R, Biavasco R, Stefanoni D, Nemkov T, Dom?nguez-Andr?s J, Arts RJ, Merelli I, Mazza D, Zambrano S, Panigada M, Cantoni E, Tengesdal IW, Maksud P, Piras F, Cesana D, Cassina L, Distefano G, Loffreda A, Gnani D, De Luca G, Tomelleri A, Campochiaro C, Joosten LAB, Dinarello CA, Kajaste-Rudnitski A, Haroche J, Cardaci S, Cenci S, Dagna L, Doglioni C, Ferrarini M, Ferrero E, Boletta A, D'Alessandro A, Montini E, Netea MG, Cavalli G. Oncogene-induced maladaptive activation of trained immunity in the pathogenesis and treatment of Erdheim-Chester disease. Blood. 2021 10 28; 138(17):1554-1569.
Score: 0.030
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V?zquez-Torres A, Fantuzzi G, Edwards CK, Dinarello CA, Fang FC. Defective localization of the NADPH phagocyte oxidase to Salmonella-containing phagosomes in tumor necrosis factor p55 receptor-deficient macrophages. Proc Natl Acad Sci U S A. 2001 Feb 27; 98(5):2561-5.
Score: 0.028
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Reznikov LL, Kim SH, Westcott JY, Frishman J, Fantuzzi G, Novick D, Rubinstein M, Dinarello CA. IL-18 binding protein increases spontaneous and IL-1-induced prostaglandin production via inhibition of IFN-gamma. Proc Natl Acad Sci U S A. 2000 Feb 29; 97(5):2174-9.
Score: 0.026
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S?nchez-Fern?ndez A, Skouras DB, Dinarello CA, L?pez-Vales R. OLT1177 (Dapansutrile), a Selective NLRP3 Inflammasome Inhibitor, Ameliorates Experimental Autoimmune Encephalomyelitis Pathogenesis. Front Immunol. 2019; 10:2578.
Score: 0.026
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Dinarello CA. Interleukin-18. Methods. 1999 Sep; 19(1):121-32.
Score: 0.026
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Fantuzzi G, Dinarello CA. Interleukin-18 and interleukin-1 beta: two cytokine substrates for ICE (caspase-1). J Clin Immunol. 1999 Jan; 19(1):1-11.
Score: 0.024
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Kaplanov I, Carmi Y, Kornetsky R, Shemesh A, Shurin GV, Shurin MR, Dinarello CA, Voronov E, Apte RN. Blocking IL-1? reverses the immunosuppression in mouse breast cancer and synergizes with anti-PD-1 for tumor abrogation. Proc Natl Acad Sci U S A. 2019 01 22; 116(4):1361-1369.
Score: 0.024
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Arts RJ, Novakovic B, Ter Horst R, Carvalho A, Bekkering S, Lachmandas E, Rodrigues F, Silvestre R, Cheng SC, Wang SY, Habibi E, Gon?alves LG, Mesquita I, Cunha C, van Laarhoven A, van de Veerdonk FL, Williams DL, van der Meer JW, Logie C, O'Neill LA, Dinarello CA, Riksen NP, van Crevel R, Clish C, Notebaart RA, Joosten LA, Stunnenberg HG, Xavier RJ, Netea MG. Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity. Cell Metab. 2016 12 13; 24(6):807-819.
Score: 0.021
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Ter Horst R, Jaeger M, Smeekens SP, Oosting M, Swertz MA, Li Y, Kumar V, Diavatopoulos DA, Jansen AFM, Lemmers H, Toenhake-Dijkstra H, van Herwaarden AE, Janssen M, van der Molen RG, Joosten I, Sweep FCGJ, Smit JW, Netea-Maier RT, Koenders MMJF, Xavier RJ, van der Meer JWM, Dinarello CA, Pavelka N, Wijmenga C, Notebaart RA, Joosten LAB, Netea MG. Host and Environmental Factors Influencing Individual Human Cytokine Responses. Cell. 2016 11 03; 167(4):1111-1124.e13.
Score: 0.021
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Bekkering S, van den Munckhof I, Nielen T, Lamfers E, Dinarello C, Rutten J, de Graaf J, Joosten LA, Netea MG, Gomes ME, Riksen NP. Innate immune cell activation and epigenetic remodeling in symptomatic and asymptomatic atherosclerosis in humans in?vivo. Atherosclerosis. 2016 11; 254:228-236.
Score: 0.021
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Fantuzzi G, Zheng H, Faggioni R, Benigni F, Ghezzi P, Sipe JD, Shaw AR, Dinarello CA. Effect of endotoxin in IL-1 beta-deficient mice. J Immunol. 1996 Jul 01; 157(1):291-6.
Score: 0.021
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Iannitti RG, Napolioni V, Oikonomou V, De Luca A, Galosi C, Pariano M, Massi-Benedetti C, Borghi M, Puccetti M, Lucidi V, Colombo C, Fiscarelli E, Lass-Fl?rl C, Majo F, Cariani L, Russo M, Porcaro L, Ricciotti G, Ellemunter H, Ratclif L, De Benedictis FM, Talesa VN, Dinarello CA, van de Veerdonk FL, Romani L. IL-1 receptor antagonist ameliorates inflammasome-dependent inflammation in murine and human cystic fibrosis. Nat Commun. 2016 Mar 14; 7:10791.
Score: 0.020
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Shapiro L, Dinarello CA. Osmotic regulation of cytokine synthesis in vitro. Proc Natl Acad Sci U S A. 1995 Dec 19; 92(26):12230-4.
Score: 0.020
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Tilg H, Atkins MB, Dinarello CA, Mier JW. Induction of circulating interleukin 10 by interleukin 1 and interleukin 2, but not interleukin 6 immunotherapy. Cytokine. 1995 Oct; 7(7):734-9.
Score: 0.019
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Rider P, Carmi Y, Yossef R, Guttman O, Eini H, Azam T, Dinarello CA, Lewis EC. IL-1 Receptor Antagonist Chimeric Protein: Context-Specific and Inflammation-Restricted Activation. J Immunol. 2015 Aug 15; 195(4):1705-12.
Score: 0.019
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Ballak DB, van Diepen JA, Moschen AR, Jansen HJ, Hijmans A, Groenhof GJ, Leenders F, Bufler P, Boekschoten MV, M?ller M, Kersten S, Li S, Kim S, Eini H, Lewis EC, Joosten LA, Tilg H, Netea MG, Tack CJ, Dinarello CA, Stienstra R. IL-37 protects against obesity-induced inflammation and insulin resistance. Nat Commun. 2014 Sep 03; 5:4711.
Score: 0.018
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Heinhuis B, Popa CD, van Tits BL, Kim SH, Zeeuwen PL, van den Berg WB, van der Meer JW, van der Vliet JA, Stalenhoef AF, Dinarello CA, Netea MG, Joosten LA. Towards a role of interleukin-32 in atherosclerosis. Cytokine. 2013 Oct; 64(1):433-40.
Score: 0.017
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Rider P, Carmi Y, Guttman O, Braiman A, Cohen I, Voronov E, White MR, Dinarello CA, Apte RN. IL-1a and IL-1? recruit different myeloid cells and promote different stages of sterile inflammation. J Immunol. 2011 Nov 01; 187(9):4835-43.
Score: 0.015
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Keswani A, Chustz RT, Suh L, Carter R, Peters AT, Tan BK, Chandra R, Kim SH, Azam T, Dinarello CA, Kern RC, Schleimer RP, Kato A. Differential expression of interleukin-32 in chronic rhinosinusitis with and without nasal polyps. Allergy. 2012 Jan; 67(1):25-32.
Score: 0.015
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Molina JM, Schindler R, Ferriani R, Sakaguchi M, Vannier E, Dinarello CA, Groopman JE. Production of cytokines by peripheral blood monocytes/macrophages infected with human immunodeficiency virus type 1 (HIV-1). J Infect Dis. 1990 May; 161(5):888-93.
Score: 0.013
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Okamoto M, Liu W, Luo Y, Tanaka A, Cai X, Norris DA, Dinarello CA, Fujita M. Constitutively active inflammasome in human melanoma cells mediating autoinflammation via caspase-1 processing and secretion of interleukin-1beta. J Biol Chem. 2010 Feb 26; 285(9):6477-88.
Score: 0.013
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Joosten LA, Netea MG, Fantuzzi G, Koenders MI, Helsen MM, Sparrer H, Pham CT, van der Meer JW, Dinarello CA, van den Berg WB. Inflammatory arthritis in caspase 1 gene-deficient mice: contribution of proteinase 3 to caspase 1-independent production of bioactive interleukin-1beta. Arthritis Rheum. 2009 Dec; 60(12):3651-62.
Score: 0.013
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Hong J, Bae S, Kang Y, Yoon D, Bai X, Chan ED, Azam T, Dinarello CA, Lee S, Her E, Rho G, Kim S. Suppressing IL-32 in monocytes impairs the induction of the proinflammatory cytokines TNFalpha and IL-1beta. Cytokine. 2010 Feb; 49(2):171-6.
Score: 0.013
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Bani-Hani AH, Leslie JA, Asanuma H, Dinarello CA, Campbell MT, Meldrum DR, Zhang H, Hile K, Meldrum KK. IL-18 neutralization ameliorates obstruction-induced epithelial-mesenchymal transition and renal fibrosis. Kidney Int. 2009 Sep; 76(5):500-11.
Score: 0.013
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van de Veerdonk FL, Joosten LA, Devesa I, Mora-Montes HM, Kanneganti TD, Dinarello CA, van der Meer JW, Gow NA, Kullberg BJ, Netea MG. Bypassing pathogen-induced inflammasome activation for the regulation of interleukin-1beta production by the fungal pathogen Candida albicans. J Infect Dis. 2009 Apr 01; 199(7):1087-96.
Score: 0.012
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He Z, Lu L, Altmann C, Hoke TS, Ljubanovic D, Jani A, Dinarello CA, Faubel S, Edelstein CL. Interleukin-18 binding protein transgenic mice are protected against ischemic acute kidney injury. Am J Physiol Renal Physiol. 2008 Nov; 295(5):F1414-21.
Score: 0.012
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Cohen AB, MacArthur C, Idell S, Maunder R, Martin T, Dinarello CA, Griffith D, McLarty J. A peptide from alveolar macrophages that releases neutrophil enzymes into the lungs in patients with the adult respiratory distress syndrome. Am Rev Respir Dis. 1988 May; 137(5):1151-8.
Score: 0.012
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Zucali JR, Broxmeyer HE, Gross MA, Dinarello CA. Recombinant human tumor necrosis factors alpha and beta stimulate fibroblasts to produce hemopoietic growth factors in vitro. J Immunol. 1988 Feb 01; 140(3):840-4.
Score: 0.011
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Mandrup-Poulsen T, Egeberg J, Nerup J, Bendtzen K, Nielsen JH, Dinarello CA. Ultrastructural studies of time-course and cellular specificity of interleukin-1 mediated islet cytotoxicity. Acta Pathol Microbiol Immunol Scand C. 1987 Apr; 95(2):55-63.
Score: 0.011
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Meldrum KK, Misseri R, Metcalfe P, Dinarello CA, Hile KL, Meldrum DR. TNF-alpha neutralization ameliorates obstruction-induced renal fibrosis and dysfunction. Am J Physiol Regul Integr Comp Physiol. 2007 Apr; 292(4):R1456-64.
Score: 0.011
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Dinarello CA, Conti P, Mier JW. Effects of human interleukin-1 on natural killer cell activity: is fever a host defense mechanism for tumor killing? Yale J Biol Med. 1986 Mar-Apr; 59(2):97-106.
Score: 0.010
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Joosten LA, Netea MG, Kim SH, Yoon DY, Oppers-Walgreen B, Radstake TR, Barrera P, van de Loo FA, Dinarello CA, van den Berg WB. IL-32, a proinflammatory cytokine in rheumatoid arthritis. Proc Natl Acad Sci U S A. 2006 Feb 28; 103(9):3298-303.
Score: 0.010
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Valentine M, Lotz M, Dinarello CA, Carson DA, Vaughan JH. Lymphoblastoid B cell lines produce an interleukin-1-like activity that can be serologically distinct from macrophage interleukin-1. Lymphokine Res. 1986; 5(3):173-83.
Score: 0.010
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Pearson FC, Bohon J, Lee W, Bruszer G, Sagona M, Dawe R, Jakubowski G, Morrison D, Dinarello C. Comparison of chemical analyses of hollow-fiber dialyzer extracts. Artif Organs. 1984 Aug; 8(3):291-8.
Score: 0.009
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Wyler DJ, Stadecker MJ, Dinarello CA, O'Dea JF. Fibroblast stimulation in schistosomiasis. V. Egg granuloma macrophages spontaneously secrete a fibroblast-stimulating factor. J Immunol. 1984 Jun; 132(6):3142-8.
Score: 0.009
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Voronov E, Shouval DS, Krelin Y, Cagnano E, Benharroch D, Iwakura Y, Dinarello CA, Apte RN. IL-1 is required for tumor invasiveness and angiogenesis. Proc Natl Acad Sci U S A. 2003 Mar 04; 100(5):2645-50.
Score: 0.008
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Banda NK, Vondracek A, Kraus D, Dinarello CA, Kim SH, Bendele A, Senaldi G, Arend WP. Mechanisms of inhibition of collagen-induced arthritis by murine IL-18 binding protein. J Immunol. 2003 Feb 15; 170(4):2100-5.
Score: 0.008
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Kaser A, Novick D, Rubinstein M, Siegmund B, Enrich B, Koch RO, Vogel W, Kim SH, Dinarello CA, Tilg H. Interferon-alpha induces interleukin-18 binding protein in chronic hepatitis C patients. Clin Exp Immunol. 2002 Aug; 129(2):332-8.
Score: 0.008
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Perales MA, Fantuzzi G, Goldberg SM, Turk MJ, Mortazavi F, Busam K, Houghton AN, Dinarello CA, Wolchok JD. GM-CSF DNA induces specific patterns of cytokines and chemokines in the skin: implications for DNA vaccines. Cytokines Cell Mol Ther. 2002; 7(3):125-33.
Score: 0.008
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Faggioni R, Fantuzzi G, Gabay C, Moser A, Dinarello CA, Feingold KR, Grunfeld C. Leptin deficiency enhances sensitivity to endotoxin-induced lethality. Am J Physiol. 1999 01; 276(1):R136-42.
Score: 0.006
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Chomarat P, Vannier E, Dechanet J, Rissoan MC, Banchereau J, Dinarello CA, Miossec P. Balance of IL-1 receptor antagonist/IL-1 beta in rheumatoid synovium and its regulation by IL-4 and IL-10. J Immunol. 1995 Feb 01; 154(3):1432-9.
Score: 0.005
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Tilg H, Trehu E, Atkins MB, Dinarello CA, Mier JW. Interleukin-6 (IL-6) as an anti-inflammatory cytokine: induction of circulating IL-1 receptor antagonist and soluble tumor necrosis factor receptor p55. Blood. 1994 Jan 01; 83(1):113-8.
Score: 0.004
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Gothelf Y, Dinarello CA, Yamin M, Sharon N, Milner Y, Gazit E. IL-1 production by T6 (CD1a) positive cord blood mononuclear cells (Langerhan's cell precursors?). Lymphokine Res. 1989; 8(4):373-82.
Score: 0.003
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Bagby GC, Dinarello CA, Neerhout RC, Ridgway D, McCall E. Interleukin 1-dependent paracrine granulopoiesis in chronic granulocytic leukemia of the juvenile type. J Clin Invest. 1988 Oct; 82(4):1430-6.
Score: 0.003
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Shaldon S, Dinarello CA, Koch KM, Lonnemann G, Bingel M, Granolleras C, Deschodt G, Branger B, Oul?s R, Fourcade J. Interleukin-1 and dialysis. Adv Nephrol Necker Hosp. 1988; 17:423-34.
Score: 0.003
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Dinarello CA, Bodel PT, Atkins E. The role of the liver in the production of fever and in pyrogenic tolerance. Trans Assoc Am Physicians. 1968; 81:334-44.
Score: 0.003
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Mandrup-Poulsen T, Bendtzen K, Dinarello CA, Nerup J. Human tumor necrosis factor potentiates human interleukin 1-mediated rat pancreatic beta-cell cytotoxicity. J Immunol. 1987 Dec 15; 139(12):4077-82.
Score: 0.003
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Riveau GR, Novitsky TJ, Roslansky PF, Dinarello CA, Warren HS. Role of interleukin-1 in augmenting serum neutralization of bacterial lipopolysaccharide. J Clin Microbiol. 1987 May; 25(5):889-92.
Score: 0.003
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Hofman FM, von Hanwehr RI, Dinarello CA, Mizel SB, Hinton D, Merrill JE. Immunoregulatory molecules and IL 2 receptors identified in multiple sclerosis brain. J Immunol. 1986 May 01; 136(9):3239-45.
Score: 0.003
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Sahasrabuddhe CG, Dinarello C, Martin B, Maizel AL. Intracellular human IL-1: a precursor for the secreted monokine. Lymphokine Res. 1985; 4(3):205-13.
Score: 0.002
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Williams JM, Dinarello CA, Rosenwasser LJ, Kelley V, Reddish M, Strom TB. Phorbol myristate acetate-protein complex mimics bioactivity of human IL-1. 1. Direct evidence that PMA temporarily enters and is released from cellular compartment during superinduction protocol. Lymphokine Res. 1985; 4(4):275-97.
Score: 0.002
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Krueger JM, Walter J, Dinarello CA, Wolff SM, Chedid L. Sleep-promoting effects of endogenous pyrogen (interleukin-1). Am J Physiol. 1984 Jun; 246(6 Pt 2):R994-9.
Score: 0.002
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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