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Connection

Robert Kuchta to Substrate Specificity

This is a "connection" page, showing publications Robert Kuchta has written about Substrate Specificity.

 
Connection Strength
 
 
 
0.749
 
  1. Vashishtha AK, Kuchta RD. Effects of Acyclovir, Foscarnet, and Ribonucleotides on Herpes Simplex Virus-1 DNA Polymerase: Mechanistic Insights and a Novel Mechanism for Preventing Stable Incorporation of Ribonucleotides into DNA. Biochemistry. 2016 Feb 23; 55(7):1168-77.
    View in: PubMed
    Score: 0.124
  2. Urban M, Joubert N, Purse BW, Hocek M, Kuchta RD. Mechanisms by which human DNA primase chooses to polymerize a nucleoside triphosphate. Biochemistry. 2010 Feb 02; 49(4):727-35.
    View in: PubMed
    Score: 0.082
  3. Urban M, Joubert N, Hocek M, Alexander RE, Kuchta RD. Herpes simplex virus-1 DNA primase: a remarkably inaccurate yet selective polymerase. Biochemistry. 2009 Nov 24; 48(46):10866-81.
    View in: PubMed
    Score: 0.080
  4. Trostler M, Delier A, Beckman J, Urban M, Patro JN, Spratt TE, Beese LS, Kuchta RD. Discrimination between right and wrong purine dNTPs by DNA polymerase I from Bacillus stearothermophilus. Biochemistry. 2009 Jun 02; 48(21):4633-41.
    View in: PubMed
    Score: 0.078
  5. Beckman J, Kincaid K, Hocek M, Spratt T, Engels J, Cosstick R, Kuchta RD. Human DNA polymerase alpha uses a combination of positive and negative selectivity to polymerize purine dNTPs with high fidelity. Biochemistry. 2007 Jan 16; 46(2):448-60.
    View in: PubMed
    Score: 0.066
  6. Ramirez-Aguilar KA, Moore CL, Kuchta RD. Herpes simplex virus 1 primase employs watson-crick hydrogen bonding to identify cognate nucleoside triphosphates. Biochemistry. 2005 Nov 29; 44(47):15585-93.
    View in: PubMed
    Score: 0.061
  7. Kincaid K, Beckman J, Zivkovic A, Halcomb RL, Engels JW, Kuchta RD. Exploration of factors driving incorporation of unnatural dNTPS into DNA by Klenow fragment (DNA polymerase I) and DNA polymerase alpha. Nucleic Acids Res. 2005; 33(8):2620-8.
    View in: PubMed
    Score: 0.059
  8. Moore CL, Zivkovic A, Engels JW, Kuchta RD. Human DNA primase uses Watson-Crick hydrogen bonds to distinguish between correct and incorrect nucleoside triphosphates. Biochemistry. 2004 Sep 28; 43(38):12367-74.
    View in: PubMed
    Score: 0.056
  9. Catalano CE, Kuchta RD. Inactivation of DNA polymerase alpha-primase by acrolein: loss of activity depends on the DNA substrate. Biochem Biophys Res Commun. 1995 Sep 25; 214(3):971-7.
    View in: PubMed
    Score: 0.030
  10. Ilsley DD, Lee SH, Miller WH, Kuchta RD. Acyclic guanosine analogs inhibit DNA polymerases alpha, delta, and epsilon with very different potencies and have unique mechanisms of action. Biochemistry. 1995 Feb 28; 34(8):2504-10.
    View in: PubMed
    Score: 0.029
  11. Cheng CH, Kuchta RD. DNA polymerase epsilon: aphidicolin inhibition and the relationship between polymerase and exonuclease activity. Biochemistry. 1993 Aug 24; 32(33):8568-74.
    View in: PubMed
    Score: 0.026
  12. Sheaff R, Ilsley D, Kuchta R. Mechanism of DNA polymerase alpha inhibition by aphidicolin. Biochemistry. 1991 Sep 03; 30(35):8590-7.
    View in: PubMed
    Score: 0.023
  13. Kuchta RD, Benkovic P, Benkovic SJ. Kinetic mechanism whereby DNA polymerase I (Klenow) replicates DNA with high fidelity. Biochemistry. 1988 Sep 06; 27(18):6716-25.
    View in: PubMed
    Score: 0.018
  14. Kuchta RD, Mizrahi V, Benkovic PA, Johnson KA, Benkovic SJ. Kinetic mechanism of DNA polymerase I (Klenow). Biochemistry. 1987 Dec 15; 26(25):8410-7.
    View in: PubMed
    Score: 0.018
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

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