 Connection
Robert Batey to Ligands
This is a "connection" page, showing publications Robert Batey has written about Ligands.
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Connection Strength |
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3.598 |
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Olenginski LT, Spradlin SF, Batey RT. Flipping the script: Understanding riboswitches from an alternative perspective. J Biol Chem. 2024 03; 300(3):105730.
Score: 0.704
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Spradlin SF, Dickerson KA, Batey RT. Structural and functional clues challenge the hypothesis that the yjdF riboswitch is natively regulated through broad recognition of azaaromatic compounds. Nucleic Acids Res. 2025 Nov 13; 53(21).
Score: 0.199
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Olenginski LT, Wierzba AJ, Laursen SP, Batey RT. Designing small molecules targeting a cryptic RNA binding site through base displacement. Nat Chem Biol. 2026 Jun; 22(6):1004-1013.
Score: 0.196
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Lennon SR, Wierzba AJ, Siwik SH, Gryko D, Palmer AE, Batey RT. Targeting Riboswitches with Beta-Axial-Substituted Cobalamins. ACS Chem Biol. 2023 05 19; 18(5):1136-1147.
Score: 0.167
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Lennon SR, Batey RT. Regulation of Gene Expression Through Effector-dependent Conformational Switching by Cobalamin Riboswitches. J Mol Biol. 2022 09 30; 434(18):167585.
Score: 0.155
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Drogalis LK, Batey RT. Requirements for efficient ligand-gated co-transcriptional switching in designed variants of the B. subtilis pbuE adenine-responsive riboswitch in E. coli. PLoS One. 2020; 15(12):e0243155.
Score: 0.141
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Iwasaki RS, Batey RT. SPRINT: a Cas13a-based platform for detection of small molecules. Nucleic Acids Res. 2020 09 25; 48(17):e101.
Score: 0.139
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Matyjasik MM, Hall SD, Batey RT. High Affinity Binding of N2-Modified Guanine Derivatives Significantly Disrupts the Ligand Binding Pocket of the Guanine Riboswitch. Molecules. 2020 May 13; 25(10).
Score: 0.136
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Matyjasik MM, Batey RT. Structural basis for 2'-deoxyguanosine recognition by the 2'-dG-II class of riboswitches. Nucleic Acids Res. 2019 11 18; 47(20):10931-10941.
Score: 0.131
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Polaski JT, Kletzien OA, Drogalis LK, Batey RT. A functional genetic screen reveals sequence preferences within a key tertiary interaction in cobalamin riboswitches required for ligand selectivity. Nucleic Acids Res. 2018 09 28; 46(17):9094-9105.
Score: 0.121
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Vicens Q, Mondragón E, Reyes FE, Coish P, Aristoff P, Berman J, Kaur H, Kells KW, Wickens P, Wilson J, Gadwood RC, Schostarez HJ, Suto RK, Blount KF, Batey RT. Structure-Activity Relationship of Flavin Analogues That Target the Flavin Mononucleotide Riboswitch. ACS Chem Biol. 2018 10 19; 13(10):2908-2919.
Score: 0.121
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Polaski JT, Webster SM, Johnson JE, Batey RT. Cobalamin riboswitches exhibit a broad range of ability to discriminate between methylcobalamin and adenosylcobalamin. J Biol Chem. 2017 07 14; 292(28):11650-11658.
Score: 0.110
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Stoddard CD, Widmann J, Trausch JJ, Marcano-Velázquez JG, Knight R, Batey RT. Nucleotides adjacent to the ligand-binding pocket are linked to activity tuning in the purine riboswitch. J Mol Biol. 2013 May 27; 425(10):1596-611.
Score: 0.082
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Johnson JE, Reyes FE, Polaski JT, Batey RT. B12 cofactors directly stabilize an mRNA regulatory switch. Nature. 2012 Dec 06; 492(7427):133-7.
Score: 0.080
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Trausch JJ, Ceres P, Reyes FE, Batey RT. The structure of a tetrahydrofolate-sensing riboswitch reveals two ligand binding sites in a single aptamer. Structure. 2011 Oct 12; 19(10):1413-23.
Score: 0.074
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Vicens Q, Mondragón E, Batey RT. Molecular sensing by the aptamer domain of the FMN riboswitch: a general model for ligand binding by conformational selection. Nucleic Acids Res. 2011 Oct; 39(19):8586-98.
Score: 0.074
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Daldrop P, Reyes FE, Robinson DA, Hammond CM, Lilley DM, Batey RT, Brenk R. Novel ligands for a purine riboswitch discovered by RNA-ligand docking. Chem Biol. 2011 Mar 25; 18(3):324-35.
Score: 0.072
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Garst AD, Batey RT. A switch in time: detailing the life of a riboswitch. Biochim Biophys Acta. 2009 Sep-Oct; 1789(9-10):584-91.
Score: 0.064
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Gilbert SD, Reyes FE, Edwards AL, Batey RT. Adaptive ligand binding by the purine riboswitch in the recognition of guanine and adenine analogs. Structure. 2009 Jun 10; 17(6):857-68.
Score: 0.064
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Gilbert SD, Batey RT. Monitoring RNA-ligand interactions using isothermal titration calorimetry. Methods Mol Biol. 2009; 540:97-114.
Score: 0.062
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Edwards AL, Batey RT. A structural basis for the recognition of 2'-deoxyguanosine by the purine riboswitch. J Mol Biol. 2009 Jan 23; 385(3):938-48.
Score: 0.061
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Garst AD, Héroux A, Rambo RP, Batey RT. Crystal structure of the lysine riboswitch regulatory mRNA element. J Biol Chem. 2008 Aug 15; 283(33):22347-51.
Score: 0.060
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Stoddard CD, Gilbert SD, Batey RT. Ligand-dependent folding of the three-way junction in the purine riboswitch. RNA. 2008 Apr; 14(4):675-84.
Score: 0.058
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Gilbert SD, Love CE, Edwards AL, Batey RT. Mutational analysis of the purine riboswitch aptamer domain. Biochemistry. 2007 Nov 20; 46(46):13297-309.
Score: 0.057
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Stoddard CD, Batey RT. Mix-and-match riboswitches. ACS Chem Biol. 2006 Dec 15; 1(12):751-4.
Score: 0.054
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Gilbert SD, Batey RT. Riboswitches: fold and function. Chem Biol. 2006 Aug; 13(8):805-7.
Score: 0.052
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Montange RK, Batey RT. Structure of the S-adenosylmethionine riboswitch regulatory mRNA element. Nature. 2006 Jun 29; 441(7097):1172-5.
Score: 0.052
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Gilbert SD, Stoddard CD, Wise SJ, Batey RT. Thermodynamic and kinetic characterization of ligand binding to the purine riboswitch aptamer domain. J Mol Biol. 2006 Jun 09; 359(3):754-68.
Score: 0.051
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Gilbert SD, Montange RK, Stoddard CD, Batey RT. Structural studies of the purine and SAM binding riboswitches. Cold Spring Harb Symp Quant Biol. 2006; 71:259-68.
Score: 0.050
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Li C, Yang X, Dickerson KA, Zanon PRA, Springer NA, Wang J, Jia Y, Munshi NC, Batey RT, Disney MD. Structure-Guided Design of a Bioactive Covalent Small Molecule Targeting a Riboswitch. J Am Chem Soc. 2025 Oct 22; 147(42):38684-38690.
Score: 0.049
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Batey RT, Gilbert SD, Montange RK. Structure of a natural guanine-responsive riboswitch complexed with the metabolite hypoxanthine. Nature. 2004 Nov 18; 432(7015):411-5.
Score: 0.046
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Miao Z, Adamiak RW, Antczak M, Boniecki MJ, Bujnicki J, Chen SJ, Cheng CY, Cheng Y, Chou FC, Das R, Dokholyan NV, Ding F, Geniesse C, Jiang Y, Joshi A, Krokhotin A, Magnus M, Mailhot O, Major F, Mann TH, Piatkowski P, Pluta R, Popenda M, Sarzynska J, Sun L, Szachniuk M, Tian S, Wang J, Wang J, Watkins AM, Wiedemann J, Xiao Y, Xu X, Yesselman JD, Zhang D, Zhang Y, Zhang Z, Zhao C, Zhao P, Zhou Y, Zok T, Zyla A, Ren A, Batey RT, Golden BL, Huang L, Lilley DM, Liu Y, Patel DJ, Westhof E. RNA-Puzzles Round IV: 3D structure predictions of four ribozymes and two aptamers. RNA. 2020 08; 26(8):982-995.
Score: 0.034
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Miao Z, Adamiak RW, Antczak M, Batey RT, Becka AJ, Biesiada M, Boniecki MJ, Bujnicki JM, Chen SJ, Cheng CY, Chou FC, Ferré-D'Amaré AR, Das R, Dawson WK, Ding F, Dokholyan NV, Dunin-Horkawicz S, Geniesse C, Kappel K, Kladwang W, Krokhotin A, Lach GE, Major F, Mann TH, Magnus M, Pachulska-Wieczorek K, Patel DJ, Piccirilli JA, Popenda M, Purzycka KJ, Ren A, Rice GM, Santalucia J, Sarzynska J, Szachniuk M, Tandon A, Trausch JJ, Tian S, Wang J, Weeks KM, Williams B, Xiao Y, Xu X, Zhang D, Zok T, Westhof E. RNA-Puzzles Round III: 3D RNA structure prediction of five riboswitches and one ribozyme. RNA. 2017 05; 23(5):655-672.
Score: 0.027
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Holmstrom ED, Polaski JT, Batey RT, Nesbitt DJ. Single-molecule conformational dynamics of a biologically functional hydroxocobalamin riboswitch. J Am Chem Soc. 2014 Dec 03; 136(48):16832-43.
Score: 0.023
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Fiegland LR, Garst AD, Batey RT, Nesbitt DJ. Single-molecule studies of the lysine riboswitch reveal effector-dependent conformational dynamics of the aptamer domain. Biochemistry. 2012 Nov 13; 51(45):9223-33.
Score: 0.020
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Cochrane JC, Batey RT, Strobel SA. Quantitation of free energy profiles in RNA-ligand interactions by nucleotide analog interference mapping. RNA. 2003 Oct; 9(10):1282-9.
Score: 0.011
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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