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Connection

Deborah Wuttke to Telomere-Binding Proteins

This is a "connection" page, showing publications Deborah Wuttke has written about Telomere-Binding Proteins.

 
Connection Strength
 
 
 
8.765
 
  1. Olson CL, Wuttke DS. Guardians of the Genome: How the Single-Stranded DNA-Binding Proteins RPA and CST Facilitate Telomere Replication. Biomolecules. 2024 Feb 22; 14(3).
    View in: PubMed
    Score: 0.803
  2. Barbour AT, Wuttke DS. RPA-like single-stranded DNA-binding protein complexes including CST serve as specialized processivity factors for polymerases. Curr Opin Struct Biol. 2023 08; 81:102611.
    View in: PubMed
    Score: 0.763
  3. Glustrom LW, Lyon KR, Paschini M, Reyes CM, Parsonnet NV, Toro TB, Lundblad V, Wuttke DS. Single-stranded telomere-binding protein employs a dual rheostat for binding affinity and specificity that drives function. Proc Natl Acad Sci U S A. 2018 10 09; 115(41):10315-10320.
    View in: PubMed
    Score: 0.552
  4. Lloyd NR, Wuttke DS. Discrimination against RNA Backbones by a ssDNA Binding Protein. Structure. 2018 05 01; 26(5):722-733.e2.
    View in: PubMed
    Score: 0.536
  5. Hom RA, Wuttke DS. Human CST Prefers G-Rich but Not Necessarily Telomeric Sequences. Biochemistry. 2017 08 15; 56(32):4210-4218.
    View in: PubMed
    Score: 0.510
  6. Dickey TH, Wuttke DS. The telomeric protein Pot1 from Schizosaccharomyces pombe binds ssDNA in two modes with differing 3' end availability. Nucleic Acids Res. 2014 Sep; 42(15):9656-65.
    View in: PubMed
    Score: 0.414
  7. Lewis KA, Pfaff DA, Earley JN, Altschuler SE, Wuttke DS. The tenacious recognition of yeast telomere sequence by Cdc13 is fully exerted by a single OB-fold domain. Nucleic Acids Res. 2014 Jan; 42(1):475-84.
    View in: PubMed
    Score: 0.390
  8. Dickey TH, McKercher MA, Wuttke DS. Nonspecific recognition is achieved in Pot1pC through the use of multiple binding modes. Structure. 2013 Jan 08; 21(1):121-132.
    View in: PubMed
    Score: 0.369
  9. Altschuler SE, Croy JE, Wuttke DS. A small molecule inhibitor of Pot1 binding to telomeric DNA. Biochemistry. 2012 Oct 09; 51(40):7833-45.
    View in: PubMed
    Score: 0.364
  10. Lewis KA, Wuttke DS. Telomerase and telomere-associated proteins: structural insights into mechanism and evolution. Structure. 2012 Jan 11; 20(1):28-39.
    View in: PubMed
    Score: 0.347
  11. Altschuler SE, Dickey TH, Wuttke DS. Schizosaccharomyces pombe protection of telomeres 1 utilizes alternate binding modes to accommodate different telomeric sequences. Biochemistry. 2011 Sep 06; 50(35):7503-13.
    View in: PubMed
    Score: 0.337
  12. Gelinas AD, Paschini M, Reyes FE, H?roux A, Batey RT, Lundblad V, Wuttke DS. Telomere capping proteins are structurally related to RPA with an additional telomere-specific domain. Proc Natl Acad Sci U S A. 2009 Nov 17; 106(46):19298-303.
    View in: PubMed
    Score: 0.298
  13. Croy JE, Wuttke DS. Insights into the dynamics of specific telomeric single-stranded DNA recognition by Pot1pN. J Mol Biol. 2009 Apr 10; 387(4):935-48.
    View in: PubMed
    Score: 0.283
  14. Zappulla DC, Roberts JN, Goodrich KJ, Cech TR, Wuttke DS. Inhibition of yeast telomerase action by the telomeric ssDNA-binding protein, Cdc13p. Nucleic Acids Res. 2009 Feb; 37(2):354-67.
    View in: PubMed
    Score: 0.279
  15. Croy JE, Fast JL, Grimm NE, Wuttke DS. Deciphering the mechanism of thermodynamic accommodation of telomeric oligonucleotide sequences by the Schizosaccharomyces pombe protection of telomeres 1 (Pot1pN) protein. Biochemistry. 2008 Apr 15; 47(15):4345-4358.
    View in: PubMed
    Score: 0.266
  16. Eldridge AM, Wuttke DS. Probing the mechanism of recognition of ssDNA by the Cdc13-DBD. Nucleic Acids Res. 2008 Mar; 36(5):1624-33.
    View in: PubMed
    Score: 0.264
  17. Croy JE, Podell ER, Wuttke DS. A new model for Schizosaccharomyces pombe telomere recognition: the telomeric single-stranded DNA-binding activity of Pot11-389. J Mol Biol. 2006 Aug 04; 361(1):80-93.
    View in: PubMed
    Score: 0.236
  18. Theobald DL, Wuttke DS. Prediction of multiple tandem OB-fold domains in telomere end-binding proteins Pot1 and Cdc13. Structure. 2004 Oct; 12(10):1877-9.
    View in: PubMed
    Score: 0.209
  19. Anderson EM, Halsey WA, Wuttke DS. Site-directed mutagenesis reveals the thermodynamic requirements for single-stranded DNA recognition by the telomere-binding protein Cdc13. Biochemistry. 2003 Apr 08; 42(13):3751-8.
    View in: PubMed
    Score: 0.189
  20. Anderson EM, Halsey WA, Wuttke DS. Delineation of the high-affinity single-stranded telomeric DNA-binding domain of Saccharomyces cerevisiae Cdc13. Nucleic Acids Res. 2002 Oct 01; 30(19):4305-13.
    View in: PubMed
    Score: 0.182
  21. Olson CL, Barbour AT, Wuttke DS. Filling in the blanks: how the C-strand catches up to the G-strand at replicating telomeres using CST. Nat Struct Mol Biol. 2022 08; 29(8):730-733.
    View in: PubMed
    Score: 0.180
  22. Mitton-Fry RM, Anderson EM, Hughes TR, Lundblad V, Wuttke DS. Conserved structure for single-stranded telomeric DNA recognition. Science. 2002 Apr 05; 296(5565):145-7.
    View in: PubMed
    Score: 0.176
  23. Mitton-Fry RM, Wuttke DS. 1H, 13C and 15N resonance assignments of the DNA-binding domain of the essential protein Cdc13 complexed with single-stranded telomeric DNA. J Biomol NMR. 2002 Apr; 22(4):379-80.
    View in: PubMed
    Score: 0.176
  24. Zaug AJ, Lim CJ, Olson CL, Carilli MT, Goodrich KJ, Wuttke DS, Cech TR. CST does not evict elongating telomerase but prevents initiation by ssDNA binding. Nucleic Acids Res. 2021 11 18; 49(20):11653-11665.
    View in: PubMed
    Score: 0.172
  25. Lim CJ, Barbour AT, Zaug AJ, Goodrich KJ, McKay AE, Wuttke DS, Cech TR. The structure of human CST reveals a decameric assembly bound to telomeric DNA. Science. 2020 06 05; 368(6495):1081-1085.
    View in: PubMed
    Score: 0.155
  26. Rao T, Lubin JW, Armstrong GS, Tucey TM, Lundblad V, Wuttke DS. Structure of Est3 reveals a bimodal surface with differential roles in telomere replication. Proc Natl Acad Sci U S A. 2014 Jan 07; 111(1):214-8.
    View in: PubMed
    Score: 0.099
  27. Mandell EK, Gelinas AD, Wuttke DS, Lundblad V. Sequence-specific binding to telomeric DNA is not a conserved property of the Cdc13 DNA binding domain. Biochemistry. 2011 Jul 26; 50(29):6289-91.
    View in: PubMed
    Score: 0.084
  28. Moeller-McCoy CA, Wieser TA, Lubin JW, Gillespie AE, Ramirez JA, Paschini M, Wuttke DS, Lundblad V. The canonical RPA complex interacts with Est3 to regulate yeast telomerase activity. Proc Natl Acad Sci U S A. 2025 Feb 18; 122(7):e2419309122.
    View in: PubMed
    Score: 0.054
  29. Theobald DL, Cervantes RB, Lundblad V, Wuttke DS. Homology among telomeric end-protection proteins. Structure. 2003 Sep; 11(9):1049-50.
    View in: PubMed
    Score: 0.049
  30. Pinzaru AM, Hom RA, Beal A, Phillips AF, Ni E, Cardozo T, Nair N, Choi J, Wuttke DS, Sfeir A, Denchi EL. Telomere Replication Stress Induced by POT1 Inactivation Accelerates Tumorigenesis. Cell Rep. 2016 06 07; 15(10):2170-2184.
    View in: PubMed
    Score: 0.029
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

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