 2-Aminoadipic Acid
"2-Aminoadipic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA).
| Descriptor ID |
D015074
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| MeSH Number(s) |
D02.241.081.337.052.075 D12.125.119.075
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| Concept/Terms |
2-Aminoadipic Acid- 2-Aminoadipic Acid
- Acid, 2-Aminoadipic
- 2-Aminohexanedioic Acid
- 2 Aminohexanedioic Acid
- Acid, 2-Aminohexanedioic
- alpha-Aminoadipic Acid
- Acid, alpha-Aminoadipic
- alpha Aminoadipic Acid
- 2 Aminoadipic Acid
- Acid, 2 Aminoadipic
- Aminoadipic Acid, 2
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Below are MeSH descriptors whose meaning is more general than "2-Aminoadipic Acid".
Below are MeSH descriptors whose meaning is more specific than "2-Aminoadipic Acid".
This graph shows the total number of publications written about "2-Aminoadipic Acid" by people in this website by year, and whether "2-Aminoadipic Acid" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 | | 2012 | 0 | 1 | 1 | | 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "2-Aminoadipic Acid" by people in Profiles.
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Coughlin CR, Swanson MA, Spector E, Meeks NJL, Kronquist KE, Aslamy M, Wempe MF, van Karnebeek CDM, Gospe SM, Aziz VG, Tsai BP, Gao H, Nagy PL, Hyland K, van Dooren SJM, Salomons GS, Van Hove JLK. The genotypic spectrum of ALDH7A1 mutations resulting in pyridoxine dependent epilepsy: A common epileptic encephalopathy. J Inherit Metab Dis. 2019 03; 42(2):353-361.
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van Karnebeek CD, Hartmann H, Jaggumantri S, Bok LA, Cheng B, Connolly M, Coughlin CR, Das AM, Gospe SM, Jakobs C, van der Lee JH, Mercimek-Mahmutoglu S, Meyer U, Struys E, Sinclair G, Van Hove J, Collet JP, Plecko BR, Stockler S. Lysine restricted diet for pyridoxine-dependent epilepsy: first evidence and future trials. Mol Genet Metab. 2012 Nov; 107(3):335-44.
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Wilkes PT, Meschia G, Teng C, Zhu Y, Wilkening RB, Battaglia FC. The effect of an elevated maternal lysine concentration on placental lysine transport in pregnant sheep. Am J Obstet Gynecol. 2003 Nov; 189(5):1494-500.
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