 Captopril
"Captopril" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A potent and specific inhibitor of PEPTIDYL-DIPEPTIDASE A. It blocks the conversion of ANGIOTENSIN I to ANGIOTENSIN II, a vasoconstrictor and important regulator of arterial blood pressure. Captopril acts to suppress the RENIN-ANGIOTENSIN SYSTEM and inhibits pressure responses to exogenous angiotensin.
| Descriptor ID |
D002216
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| MeSH Number(s) |
D12.125.072.401.623.270
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| Concept/Terms |
Captopril- Captopril
- (S)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline
SQ-14,534- SQ-14,534
- SQ 14,534
- SQ14,534
- SQ-14534
- SQ 14534
- SQ14534
SQ-14,225- SQ-14,225
- SQ 14,225
- SQ14,225
- SQ-14225
- SQ 14225
- SQ14225
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Below are MeSH descriptors whose meaning is more general than "Captopril".
Below are MeSH descriptors whose meaning is more specific than "Captopril".
This graph shows the total number of publications written about "Captopril" by people in this website by year, and whether "Captopril" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 | | 2004 | 1 | 1 | 2 | | 2005 | 0 | 1 | 1 | | 2007 | 0 | 1 | 1 | | 2008 | 1 | 1 | 2 | | 2009 | 1 | 0 | 1 |
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Below are the most recent publications written about "Captopril" by people in Profiles.
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Roncal CA, Reungjui S, S?nchez-Lozada LG, Mu W, Sautin YY, Nakagawa T, Johnson RJ. Combination of captopril and allopurinol retards fructose-induced metabolic syndrome. Am J Nephrol. 2009; 30(5):399-404.
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Lemeire E, Borovsky D, Van Camp J, Smagghe G. Effect of ace inhibitors and TMOF on growth, development, and trypsin activity of larval Spodoptera littoralis. Arch Insect Biochem Physiol. 2008 Dec; 69(4):199-208.
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Havranek EP. From black and white to shades of gray: race and renin-angiotensin system blockade. J Am Coll Cardiol. 2008 May 13; 51(19):1872-3.
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Hoyer RJ, Leung N, Witzig TE, Lacy MQ. Treatment of diuretic refractory pleural effusions with bevacizumab in four patients with primary systemic amyloidosis. Am J Hematol. 2007 May; 82(5):409-13.
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Lottenberg R, Hassell KL. An evidence-based approach to the treatment of adults with sickle cell disease. Hematology Am Soc Hematol Educ Program. 2005; 58-65.
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Cavasin MA, Rhaleb NE, Yang XP, Carretero OA. Prolyl oligopeptidase is involved in release of the antifibrotic peptide Ac-SDKP. Hypertension. 2004 May; 43(5):1140-5.
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Rasoul S, Carretero OA, Peng H, Cavasin MA, Zhuo J, Sanchez-Mendoza A, Brigstock DR, Rhaleb NE. Antifibrotic effect of Ac-SDKP and angiotensin-converting enzyme inhibition in hypertension. J Hypertens. 2004 Mar; 22(3):593-603.
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Cadnapaphornchai MA, Rogachev B, Summer SN, Chen YC, Gera L, Stewart JM, Schrier RW. Evidence for bradykinin as a stimulator of thirst. Am J Physiol Renal Physiol. 2004 May; 286(5):F875-80.
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Schindler R, Dinarello CA, Koch KM. Angiotensin-converting-enzyme inhibitors suppress synthesis of tumour necrosis factor and interleukin 1 by human peripheral blood mononuclear cells. Cytokine. 1995 Aug; 7(6):526-33.
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Augenstein WL, Kulig KW, Rumack BH. Captopril overdose resulting in hypotension. JAMA. 1988 Jun 10; 259(22):3302-5.
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