 Glycogen Debranching Enzyme System
"Glycogen Debranching Enzyme System" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
1,4-alpha-D-Glucan-1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase/dextrin 6 alpha-D-glucanohydrolase. An enzyme system having both 4-alpha-glucanotransferase (EC 2.4.1.25) and amylo-1,6-glucosidase (EC 3.2.1.33) activities. As a transferase it transfers a segment of a 1,4-alpha-D-glucan to a new 4-position in an acceptor, which may be glucose or another 1,4-alpha-D-glucan. As a glucosidase it catalyzes the endohydrolysis of 1,6-alpha-D-glucoside linkages at points of branching in chains of 1,4-linked alpha-D-glucose residues. Amylo-1,6-glucosidase activity is deficient in glycogen storage disease type III.
| Descriptor ID |
D006004
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| MeSH Number(s) |
D08.811.277.450.420.450 D08.811.913.400.450.460.350
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Glycogen Debranching Enzyme System".
Below are MeSH descriptors whose meaning is more specific than "Glycogen Debranching Enzyme System".
This graph shows the total number of publications written about "Glycogen Debranching Enzyme System" by people in this website by year, and whether "Glycogen Debranching Enzyme System" was a major or minor topic of these publications.
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Below are the most recent publications written about "Glycogen Debranching Enzyme System" by people in Profiles.
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Sottnik JL, Mallaredy V, Chauca-Diaz A, Ritterson Lew C, Owens C, Dancik GM, Pagliarani S, Lucchiari S, Moggio M, Ripolone M, Comi GP, Frierson HF, Clouthier D, Theodorescu D. Elucidating the role of Agl in bladder carcinogenesis by generation and characterization of genetically engineered mice. Carcinogenesis. 2019 03 12; 40(1):194-201.
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Nadeau OW, Fontes JD, Carlson GM. The regulation of glycogenolysis in the brain. J Biol Chem. 2018 05 11; 293(19):7099-7107.
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Guin S, Ru Y, Agarwal N, Lew CR, Owens C, Comi GP, Theodorescu D. Loss of Glycogen Debranching Enzyme AGL Drives Bladder Tumor Growth via Induction of Hyaluronic Acid Synthesis. Clin Cancer Res. 2016 Mar 01; 22(5):1274-83.
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Guin S, Pollard C, Ru Y, Ritterson Lew C, Duex JE, Dancik G, Owens C, Spencer A, Knight S, Holemon H, Gupta S, Hansel D, Hellerstein M, Lorkiewicz P, Lane AN, Fan TW, Theodorescu D. Role in tumor growth of a glycogen debranching enzyme lost in glycogen storage disease. J Natl Cancer Inst. 2014 Apr 03; 106(5).
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Hoon-Hanks LL, Morton EA, Lybecker MC, Battisti JM, Samuels DS, Drecktrah D. Borrelia burgdorferi malQ mutants utilize disaccharides and traverse the enzootic cycle. FEMS Immunol Med Microbiol. 2012 Nov; 66(2):157-65.
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