Hindlimb Suspension
"Hindlimb Suspension" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Technique for limiting use, activity, or movement by immobilizing or restraining animal by suspending from hindlimbs or tails. This immobilization is used to simulate some effects of reduced gravity and study weightlessness physiology.
Descriptor ID |
D019417
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MeSH Number(s) |
E05.472.760.370 E05.977.400 N06.230.150.440.950.400
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Concept/Terms |
Hindlimb Suspension- Hindlimb Suspension
- Suspension, Hindlimb
- Hindlimb Unloading
- Unloading, Hindlimb
- Unloadings, Hindlimb
- Hindlimb Elevation
- Elevation, Hindlimb
- Hindlimb Immobilization
- Immobilization, Hindlimb
Skeletal Unloading- Skeletal Unloading
- Skeletal Unloadings
- Unloading, Skeletal
- Unloadings, Skeletal
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Below are MeSH descriptors whose meaning is more general than "Hindlimb Suspension".
Below are MeSH descriptors whose meaning is more specific than "Hindlimb Suspension".
This graph shows the total number of publications written about "Hindlimb Suspension" by people in this website by year, and whether "Hindlimb Suspension" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2000 | 1 | 0 | 1 | 2002 | 0 | 1 | 1 | 2005 | 3 | 0 | 3 | 2008 | 1 | 1 | 2 | 2010 | 0 | 1 | 1 | 2012 | 1 | 1 | 2 | 2013 | 2 | 0 | 2 | 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Hindlimb Suspension" by people in Profiles.
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Cadena SM, Zhang Y, Fang J, Brachat S, Kuss P, Giorgetti E, Stodieck LS, Kneissel M, Glass DJ. Skeletal muscle in MuRF1 null mice is not spared in low-gravity conditions, indicating atrophy proceeds by unique mechanisms in space. Sci Rep. 2019 06 28; 9(1):9397.
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Munroe M, Dvoretskiy S, Lopez A, Leong J, Dyle MC, Kong H, Adams CM, Boppart MD. Pericyte transplantation improves skeletal muscle recovery following hindlimb immobilization. FASEB J. 2019 06; 33(6):7694-7706.
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Morel JL, Dabertrand F, Porte Y, Prevot A, Macrez N. Up-regulation of ryanodine receptor expression increases the calcium-induced calcium release and spontaneous calcium signals in cerebral arteries from hindlimb unloaded rats. Pflugers Arch. 2014 Aug; 466(8):1517-28.
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Fox DK, Ebert SM, Bongers KS, Dyle MC, Bullard SA, Dierdorff JM, Kunkel SD, Adams CM. p53 and ATF4 mediate distinct and additive pathways to skeletal muscle atrophy during limb immobilization. Am J Physiol Endocrinol Metab. 2014 Aug 01; 307(3):E245-61.
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Sung M, Li J, Spieker AJ, Spatz J, Ellman R, Ferguson VL, Bateman TA, Rosen GD, Bouxsein M, Rutkove SB. Spaceflight and hind limb unloading induce similar changes in electrical impedance characteristics of mouse gastrocnemius muscle. J Musculoskelet Neuronal Interact. 2013 Dec; 13(4):405-11.
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Hanson AM, Harrison BC, Young MH, Stodieck LS, Ferguson VL. Longitudinal characterization of functional, morphologic, and biochemical adaptations in mouse skeletal muscle with hindlimb suspension. Muscle Nerve. 2013 Sep; 48(3):393-402.
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Rodgers AB, Morgan CP, Bronson SL, Revello S, Bale TL. Paternal stress exposure alters sperm microRNA content and reprograms offspring HPA stress axis regulation. J Neurosci. 2013 May 22; 33(21):9003-12.
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Yarrow JF, McCoy SC, Ferreira JA, Pingel JE, Conrad BP, Wronski TJ, Williams AA, Borst SE, Brown M. A rehabilitation exercise program induces severe bone mineral deficits in estrogen-deficient rats after extended disuse. Menopause. 2012 Nov; 19(11):1267-76.
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Stodieck LS, Greybeck BJ, Cannon CM, Hanson AM, Young MH, Simske SJ, Ferguson VL. In vivo measurement of hindlimb neuromuscular function in mice. Muscle Nerve. 2012 Apr; 45(4):536-43.
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Dabertrand F, Porte Y, Macrez N, Morel JL. Spaceflight regulates ryanodine receptor subtype 1 in portal vein myocytes in the opposite way of hypertension. J Appl Physiol (1985). 2012 Feb; 112(3):471-80.
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