Craniopharyngioma
"Craniopharyngioma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A benign pituitary-region neoplasm that originates from Rathke's pouch. The two major histologic and clinical subtypes are adamantinous (or classical) craniopharyngioma and papillary craniopharyngioma. The adamantinous form presents in children and adolescents as an expanding cystic lesion in the pituitary region. The cystic cavity is filled with a black viscous substance and histologically the tumor is composed of adamantinomatous epithelium and areas of calcification and necrosis. Papillary craniopharyngiomas occur in adults, and histologically feature a squamous epithelium with papillations. (From Joynt, Clinical Neurology, 1998, Ch14, p50)
| Descriptor ID |
D003397
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| MeSH Number(s) |
C04.557.465.625.200 C04.557.580.625.200
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| Concept/Terms |
Craniopharyngioma- Craniopharyngioma
- Craniopharyngiomas
- Neoplasm, Rathke's Cleft
- Neoplasm, Rathkes Cleft
- Rathke's Pouch Tumor
- Rathkes Pouch Tumor
- Tumor, Rathke's Pouch
- Rathke Pouch Tumor
- Tumor, Rathke Pouch
- Rathke's Cleft Neoplasm
- Rathkes Cleft Neoplasm
- Neoplasm, Rathke Cleft
- Rathke Cleft Neoplasm
Craniopharyngioma, Papillary- Craniopharyngioma, Papillary
- Craniopharyngiomas, Papillary
- Papillary Craniopharyngioma
- Papillary Craniopharyngiomas
Craniopharyngioma, Child- Craniopharyngioma, Child
- Child Craniopharyngioma
- Child Craniopharyngiomas
- Craniopharyngiomas, Child
Craniopharyngioma, Adamantinous- Craniopharyngioma, Adamantinous
- Adamantinous Craniopharyngioma
- Adamantinous Craniopharyngiomas
- Craniopharyngiomas, Adamantinous
Craniopharyngioma, Adult- Craniopharyngioma, Adult
- Adult Craniopharyngioma
- Adult Craniopharyngiomas
- Craniopharyngiomas, Adult
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Below are MeSH descriptors whose meaning is more general than "Craniopharyngioma".
Below are MeSH descriptors whose meaning is more specific than "Craniopharyngioma".
This graph shows the total number of publications written about "Craniopharyngioma" by people in this website by year, and whether "Craniopharyngioma" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 | | 2000 | 1 | 0 | 1 | | 2004 | 0 | 1 | 1 | | 2005 | 1 | 0 | 1 | | 2007 | 1 | 0 | 1 | | 2009 | 1 | 0 | 1 | | 2012 | 1 | 0 | 1 | | 2014 | 1 | 0 | 1 | | 2015 | 1 | 0 | 1 | | 2016 | 1 | 0 | 1 | | 2017 | 2 | 0 | 2 | | 2018 | 2 | 0 | 2 | | 2019 | 2 | 0 | 2 | | 2020 | 4 | 0 | 4 | | 2021 | 1 | 0 | 1 | | 2023 | 2 | 0 | 2 | | 2024 | 3 | 0 | 3 | | 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Craniopharyngioma" by people in Profiles.
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Prince EW, Mirsky DM, Hankinson TC, Görg C. Impact of AI Decision Support on Clinical Experts' Radiographic Interpretation of Adamantinomatous Craniopharyngioma. AMIA Annu Symp Proc. 2024; 2024:930-939.
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Brooks T, Gao D, Dorris K, Boone K, Mirsky DM, Staulcup S, Prince E, Moskalenko M, Ignowski E, Wandrey N, Fakhoury K, Hankinson TC, Milgrom SA. Does pre-irradiation gross tumor volume predict the risk of progression after radiation therapy in pediatric patients with adamantinomatous craniopharyngioma? J Neurosurg Pediatr. 2024 Dec 01; 34(6):642-648.
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Apps JR, Gonzalez-Meljem JM, Guiho R, Pickles JC, Prince E, Schwalbe E, Joshi N, Stone TJ, Ogunbiyi O, Chalker J, Bassey A, Otto G, Davies R, Hughes D, Brandner S, Tan E, Lee V, Hayhurst C, Kline C, Castellano S, Hankinson T, Deutschbein T, Jacques TS, Martinez-Barbera JP. Recurrent adamantinomatous craniopharyngiomas show MAPK pathway activation, clonal evolution and rare TP53-loss-mediated malignant progression. Acta Neuropathol Commun. 2024 08 10; 12(1):127.
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Prince EW, Apps JR, Jeang J, Chee K, Medlin S, Jackson EM, Dudley R, Limbrick D, Naftel R, Johnston J, Feldstein N, Prolo LM, Ginn K, Niazi T, Smith A, Kilburn L, Chern J, Leonard J, Lam S, Hersh DS, Gonzalez-Meljem JM, Amani V, Donson AM, Mitra SS, Bandopadhayay P, Martinez-Barbera JP, Hankinson TC. Unraveling the complexity of the senescence-associated secretory phenotype in adamantinomatous craniopharyngioma using multimodal machine learning analysis. Neuro Oncol. 2024 06 03; 26(6):1109-1123.
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Apps JR, Muller HL, Hankinson TC, Yock TI, Martinez-Barbera JP. Contemporary Biological Insights and Clinical Management of Craniopharyngioma. Endocr Rev. 2023 05 08; 44(3):518-538.
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Hoffman LM, Jaimes C, Mankad K, Mirsky DM, Tamrazi B, Tinkle CL, Kline C, Ramasubramanian A, Malbari F, Mangum R, Lindsay H, Horne V, Daniels DJ, Keole S, Grosshans DR, Young Poussaint T, Packer R, Cavalheiro S, Bison B, Hankinson TC, Müller HL, Bartels U, Warren KE, Chintagumpala M. Response assessment in pediatric craniopharyngioma: recommendations from the Response Assessment in Pediatric Neuro-Oncology (RAPNO) Working Group. Neuro Oncol. 2023 02 14; 25(2):224-233.
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Hankinson TC. Editorial: Characteristics and overall survival in pediatric versus adult craniopharyngioma: a population-based study. Childs Nerv Syst. 2021 06; 37(6):1823-1824.
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Prince EW, Whelan R, Mirsky DM, Stence N, Staulcup S, Klimo P, Anderson RCE, Niazi TN, Grant G, Souweidane M, Johnston JM, Jackson EM, Limbrick DD, Smith A, Drapeau A, Chern JJ, Kilburn L, Ginn K, Naftel R, Dudley R, Tyler-Kabara E, Jallo G, Handler MH, Jones K, Donson AM, Foreman NK, Hankinson TC. Robust deep learning classification of adamantinomatous craniopharyngioma from limited preoperative radiographic images. Sci Rep. 2020 10 09; 10(1):16885.
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Martinez NL, Khanna O, Farrell CJ. A narrative review of targeted therapy in meningioma, pituitary adenoma, and craniopharyngioma of the skull base. Chin Clin Oncol. 2020 Dec; 9(6):75.
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Whelan R, Hengartner A, Folzenlogen Z, Prince E, Hankinson TC. Adamantinomatous craniopharyngioma in the molecular age and the potential of targeted therapies: a review. Childs Nerv Syst. 2020 08; 36(8):1635-1642.
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