 Cleft Lip
"Cleft Lip" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Congenital defect in the upper lip where the maxillary prominence fails to merge with the merged medial nasal prominences. It is thought to be caused by faulty migration of the mesoderm in the head region.
| Descriptor ID |
D002971
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| MeSH Number(s) |
C07.465.409.225 C07.465.525.164 C07.650.525.164 C16.131.850.525.164
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| Concept/Terms |
Cleft Lip- Cleft Lip
- Cleft Lips
- Lip, Cleft
- Lips, Cleft
- Harelip
- Harelips
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Below are MeSH descriptors whose meaning is more general than "Cleft Lip".
Below are MeSH descriptors whose meaning is more specific than "Cleft Lip".
This graph shows the total number of publications written about "Cleft Lip" by people in this website by year, and whether "Cleft Lip" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 | | 1998 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2007 | 2 | 0 | 2 | | 2008 | 1 | 1 | 2 | | 2009 | 2 | 1 | 3 | | 2011 | 0 | 1 | 1 | | 2012 | 1 | 0 | 1 | | 2013 | 3 | 1 | 4 | | 2014 | 4 | 0 | 4 | | 2015 | 2 | 0 | 2 | | 2017 | 1 | 0 | 1 | | 2018 | 2 | 2 | 4 | | 2019 | 3 | 2 | 5 | | 2020 | 5 | 1 | 6 | | 2022 | 1 | 0 | 1 | | 2024 | 2 | 0 | 2 | | 2025 | 5 | 1 | 6 | | 2026 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cleft Lip" by people in Profiles.
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Kim BJ, Hernández-García A, Curtis DL, Thompson O, Champaigne N, Priolo M, Radio FC, Tartaglia M, Gucsavas-Calikoglu M, Shiloh-Malawsky Y, Perilla-Young Y, Josephi-Taylor S, Bournazos AM, Cooper ST, van Gassen K, van den Boogaard MJ, Ozekin YH, Bates EA, Kongchan N, Hsu CW, Scott DA. SPEN deficiency contributes to the development of orofacial clefts in humans and mice. Hum Mol Genet. 2026 Jul 15; 35(15).
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Mossey PA, Owens WR, Mohan VC, Shick EA, Dominguez M. Advances in the Prevention of Dental Caries in Orofacial Clefts. Plast Reconstr Surg. 2025 10 01; 156(4S-2):41S-49S.
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Hernández-García A, Kim BJ, Chitayat D, Shannon P, Hedges S, Al Bandari M, Guillen Sacoto MJ, Bates EA, Ozekin YH, Faundes V, Luna PN, Shaw CA, Rasmussen TL, Hsu CW, Scott DA. WNT4 deficiency impacts heart, diaphragm, and palate development: Insights from human genetics, machine learning, and mouse models. Dev Biol. 2026 Jan; 529:66-80.
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Kahan RH, Palmer SK, Garoosi K, Gomez DA, Khechoyan DY, French B, Lowe K, Nguyen PD. Alveolar Bone Grafting: Outcomes Utilizing Synthetic HA/TCP and rhBMP-2 versus Autologous Graft Types. Plast Reconstr Surg. 2026 01 01; 157(1):129-138.
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Chaij JM, Hammond JB, Palmer SK, Lee AD, Gomez DA, French BM, Nguyen PD, Mathes DW, Khechoyan DY. Is the Future of Cleft Care Financially Sustainable? An Economic Analysis of Inflation-Adjusted Reimbursements. Cleft Palate Craniofac J. 2026 May; 63(5):1071-1076.
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Gomez DA, Palmer SK, Andrews M, Porras AR, Yu JW, Khechoyan DY, French B, Nguyen PD. Care Pathways for Undocumented Migrant Children Seeking Cleft Lip and Palate Care: Institutional Experience, Current State Policies, and Opportunities. Cleft Palate Craniofac J. 2026 May; 63(5):973-980.
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Lee AD, Murphy M, Tin G, Alder C, Chaij J, Porras A, Yu J, French B, Lowe K, Nguyen PD, Mathes D, Khechoyan D. Trends of Staged Versus Single-Stage Operations for Bilateral Cleft Lip Repair: Analysis of a National Database. J Craniofac Surg. 2025 06 01; 36(4):1246-1248.
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Fairmont I, Tholen K, Hanson R, Patterson B, Herrmann B, Francom C. The presence of a submucous cleft palate in patients with isolated cleft lip and middle ear dysfunction. Am J Otolaryngol. 2024 Jul-Aug; 45(4):104281.
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Lowe KM, Schuster L, Oberoi S, Zinn IM. Orthodontic management of patients with cleft lip and palate: Phase I treatment. J Clin Orthod. 2024 04; 58(4):243-248.
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Shull LC, Artinger KB. Epigenetic regulation of craniofacial development and disease. Birth Defects Res. 2024 Jan; 116(1):e2271.
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