 Hypoplastic Left Heart Syndrome
"Hypoplastic Left Heart Syndrome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A condition caused by underdevelopment of the whole left half of the heart. It is characterized by hypoplasia of the left cardiac chambers (HEART ATRIUM; HEART VENTRICLE), the AORTA, the AORTIC VALVE, and the MITRAL VALVE. Severe symptoms appear in early infancy when DUCTUS ARTERIOSUS closes.
| Descriptor ID |
D018636
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| MeSH Number(s) |
C14.240.400.625 C14.280.400.625 C16.131.240.400.625
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Hypoplastic Left Heart Syndrome".
Below are MeSH descriptors whose meaning is more specific than "Hypoplastic Left Heart Syndrome".
This graph shows the total number of publications written about "Hypoplastic Left Heart Syndrome" by people in this website by year, and whether "Hypoplastic Left Heart Syndrome" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 | | 1996 | 2 | 1 | 3 | | 1997 | 1 | 0 | 1 | | 1998 | 1 | 0 | 1 | | 2000 | 1 | 0 | 1 | | 2003 | 3 | 0 | 3 | | 2004 | 1 | 0 | 1 | | 2005 | 1 | 0 | 1 | | 2006 | 1 | 0 | 1 | | 2007 | 1 | 0 | 1 | | 2008 | 2 | 1 | 3 | | 2009 | 2 | 0 | 2 | | 2010 | 3 | 0 | 3 | | 2011 | 1 | 0 | 1 | | 2012 | 2 | 1 | 3 | | 2013 | 4 | 0 | 4 | | 2014 | 7 | 0 | 7 | | 2015 | 3 | 0 | 3 | | 2016 | 1 | 0 | 1 | | 2017 | 1 | 1 | 2 | | 2018 | 3 | 0 | 3 | | 2019 | 2 | 0 | 2 | | 2020 | 3 | 1 | 4 | | 2021 | 2 | 0 | 2 | | 2022 | 2 | 0 | 2 | | 2024 | 2 | 1 | 3 | | 2025 | 2 | 0 | 2 |
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Below are the most recent publications written about "Hypoplastic Left Heart Syndrome" by people in Profiles.
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Gallego-Navarro C, Jaggers J, Burkhart HM, Carlo WF, Morales DL, Qureshi MY, Rossano JW, Hagen CE, Seisler DK, Peral SC, Nelson TJ. Autologous umbilical cord blood mononuclear cell therapy for hypoplastic left heart syndrome: a nonrandomized control trial of the efficacy and safety of intramyocardial injections. Stem Cell Res Ther. 2025 May 01; 16(1):215.
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Soszyn N, Minocha PK, Frank B, Mejia E, Zablah JE, Morgan GJ. Impact of echocardiographic and computed-tomography assessment of Sano shunt stenosis on need for percutaneous intervention. Int J Cardiovasc Imaging. 2025 May; 41(5):859-868.
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Dib N, Poirier N, Samuel M, Hermann Honfo S, Zaidi A, Opotowsky AR, Mongeon FP, Mond?sert B, Kay J, Ibrahim R, Hamilton RM, Fournier A, Jameson SM, Dore A, Cook S, Cohen S, Chaix MA, Broberg CS, Aboulhosn J, Khairy P. Cardiovascular Outcomes Associated With Hypoplastic Left Heart Syndrome Versus Other Types of Single Right Ventricle: A Multicenter Study. J Am Heart Assoc. 2024 Dec 03; 13(23):e034757.
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Sch?fer M, Di Maria MV, Stone ML, Barker AJ, Carmody KK, Reece TB, Ivy DD, Jaggers J, Mitchell MB. Principal component analysis identified neo-aortic diameter variations post Norwood surgery associated with the single ventricle performance and flow quality. Int J Cardiovasc Imaging. 2024 Dec; 40(12):2603-2616.
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Wautlet CK, Kops SA, Silveira LJ, Young K, Behrendt NJ, Zaretsky MV, Cuneo BF, Galan HL. Maternal-fetal comorbidities and obstetrical outcomes of fetal single ventricle cardiac defects: 10?years' experience with a multidisciplinary management protocol at a single center. Prenat Diagn. 2024 06; 44(6-7):783-795.
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Lopez KN, Morris SA, Krishnan A, Jacobs MB, Bhat AH, Chelliah A, Chiu JS, Cuneo BF, Freire G, Hornberger LK, Howley L, Husain N, Ikemba C, Kavanaugh-McHugh A, Kutty S, Lee C, McBrien A, Michelfelder EC, Pinto NM, Schwartz R, Stern KWD, Taylor C, Thakur V, Tworetzky W, Wittlieb-Weber C, Woldu K, Donofrio MT, Peyvandi S. Associations Between Maternal Sociodemographics and Hospital Mortality in Newborns With Prenatally Diagnosed Hypoplastic Left Heart Syndrome. Circulation. 2023 07 18; 148(3):283-285.
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Sato T, Matsubara D, Wang Y, Agger P, Pedrizzetti G, Banerjee A. Contraction Patterns of Post-Fontan Single Right Ventricle Versus Normal Left and Right Ventricles in Children: Insights From Principal Strain Analysis. J Am Soc Echocardiogr. 2023 08; 36(8):878-887.
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Schidlow DN, Gauvreau K, Bucholz EM, Bennett A, Lafranchi T, Pruetz J, Ronai C, Vergales J, Brown DW. Prenatal care coordination, racial and socioeconomic inequities, and pre- and post-operative outcomes in hypoplastic left heart syndrome. J Perinatol. 2023 03; 43(3):378-384.
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Bleiweis MS, Peek GJ, Philip J, Fudge JC, Sullivan KJ, Co-Vu J, DeGroff C, Vyas HV, Gupta D, Shih R, Pietra BBA, Fricker FJ, Cruz Beltran SC, Arnold MA, Wesley MC, Pitkin AD, Hernandez-Rivera JF, Lopez-Colon D, Barras WE, Stukov Y, Sharaf OM, Neal D, Nixon CS, Jacobs JP. A Comprehensive Approach to the Management of Patients With HLHS and Related Malformations: An Analysis of 83 Patients (2015-2021). World J Pediatr Congenit Heart Surg. 2022 09; 13(5):664-675.
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Hill MA, Mitchell MB, Rajab TK. Mitral Valve Anatomy in Patients With Native Aortic Root Thrombosis After Norwood Palliation. Ann Thorac Surg. 2022 09; 114(3):1089-1090.
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