 Progeria
"Progeria" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An abnormal congenital condition, associated with defects in the LAMIN TYPE A gene, which is characterized by premature aging in children, where all the changes of cell senescence occur. It is manifested by premature greying; hair loss; hearing loss (DEAFNESS); cataracts (CATARACT); ARTHRITIS; OSTEOPOROSIS; DIABETES MELLITUS; atrophy of subcutaneous fat; skeletal hypoplasia; elevated urinary HYALURONIC ACID; and accelerated ATHEROSCLEROSIS. Many affected individuals develop malignant tumors, especially SARCOMA.
| Descriptor ID |
D011371
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| MeSH Number(s) |
C16.320.565.753 C18.452.648.753
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| Concept/Terms |
Progeria- Progeria
- Hutchinson-Gilford Syndrome
- Hutchinson Gilford Syndrome
- Hutchinson Gilford Progeria Syndrome
- Hutchinson-Gilford Progeria Syndrome
- Hutchinson-Gilford Progeria Syndromes
- Progeria Syndrome, Hutchinson-Gilford
- Progeria Syndromes, Hutchinson-Gilford
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Below are MeSH descriptors whose meaning is more general than "Progeria".
Below are MeSH descriptors whose meaning is more specific than "Progeria".
This graph shows the total number of publications written about "Progeria" by people in this website by year, and whether "Progeria" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2022 | 2 | 0 | 2 |
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Below are the most recent publications written about "Progeria" by people in Profiles.
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Pe?a B, Gao S, Borin D, Del Favero G, Abdel-Hafiz M, Farahzad N, Lorenzon P, Sinagra G, Taylor MRG, Mestroni L, Sbaizero O. Cellular Biomechanic Impairment in Cardiomyocytes Carrying the Progeria Mutation: An Atomic Force Microscopy Investigation. Langmuir. 2022 12 06; 38(48):14928-14940.
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Sears RM, Roux KJ. Mechanisms of A-Type Lamin Targeting to Nuclear Ruptures Are Disrupted in LMNA- and BANF1-Associated Progerias. Cells. 2022 03 02; 11(5).
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Johnson TE. Cell biology. Rapid aging rescue? Science. 2013 Jun 14; 340(6138):1299-300.
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