 Limit of Detection
"Limit of Detection" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Concentration or quantity that is derived from the smallest measure that can be detected with reasonable certainty for a given analytical procedure.
| Descriptor ID |
D057230
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| MeSH Number(s) |
E05.318.740.872.374 N05.715.360.750.725.500 N06.850.520.830.872.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Limit of Detection".
Below are MeSH descriptors whose meaning is more specific than "Limit of Detection".
This graph shows the total number of publications written about "Limit of Detection" by people in this website by year, and whether "Limit of Detection" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 | | 2011 | 0 | 5 | 5 | | 2012 | 0 | 5 | 5 | | 2013 | 0 | 4 | 4 | | 2014 | 0 | 1 | 1 | | 2015 | 0 | 3 | 3 | | 2016 | 1 | 2 | 3 | | 2017 | 0 | 4 | 4 | | 2018 | 0 | 6 | 6 | | 2019 | 0 | 4 | 4 | | 2020 | 0 | 3 | 3 | | 2021 | 0 | 4 | 4 | | 2022 | 0 | 1 | 1 | | 2023 | 0 | 1 | 1 | | 2024 | 0 | 2 | 2 | | 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "Limit of Detection" by people in Profiles.
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Liu M, Zhang W, Li CC, Zhang D, Zhao NN, Zhang CY. Construction of a Bifunctional Single-Quantum Dot Nanosensor for Enzyme-Free Detection of N6-Methyladenosine Demethylase in Breast Cancer. Anal Chem. 2025 Nov 11; 97(44):24625-24633.
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Sempio C, Campos-Palomino J, Klawitter J, Zhao W, Huestis MA, Christians U, Klawitter J. Quantification of 11 kratom alkaloids including mitragynine and its main metabolites in human plasma using LC-MS/MS. Anal Bioanal Chem. 2025 Feb; 417(4):761-769.
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Sempio C, Campos-Palomino J, Klawitter J, Harrison A, Peters EN, MacNair L, Haghdoost M, Bonn-Miller M, Babalonis S, Huestis MA, Christians U, Klawitter J. LC-MS-MS quantification of ?8-THC, ?9-THC, THCV isomers and their main metabolites in human plasma. J Anal Toxicol. 2024 Aug 21; 48(7):499-506.
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Alluhayb AH, Severance C, Hendry-Hofer T, Bebarta VS, Logue BA. Concurrent determination of cyanide and thiocyanate in human and swine antemortem and postmortem blood by high-performance liquid chromatography-tandem mass spectrometry. Anal Bioanal Chem. 2023 Nov; 415(26):6595-6609.
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Sempio C, Almaraz-Quinones N, Jackson M, Zhao W, Wang GS, Liu Y, Leehey M, Knupp K, Klawitter J, Christians U, Klawitter J. Simultaneous Quantification of 17 Cannabinoids by LC-MS-MS in Human Plasma. J Anal Toxicol. 2022 Apr 21; 46(4):383-392.
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Donkor AB, White CW, Nick HJ, Logue BA. Analysis of sodium 2-mercaptoethane sulfonate in rat plasma using high performance liquid chromatography tandem-mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2022 Jan 15; 1189:123088.
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Sempio C, Wymore E, Palmer C, Bunik M, Henthorn TK, Christians U, Klawitter J. Detection of Cannabinoids by LC-MS-MS and ELISA in Breast Milk. J Anal Toxicol. 2021 Aug 14; 45(7):686-692.
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Mayne G, De Bloois E, Dabelea D, Christians U. Development and validation of an LC-MS/MS assay for the quantification of allopregnanolone and its progesterone-derived isomers, precursors, and cortisol/cortisone in pregnancy. Anal Bioanal Chem. 2021 Sep; 413(21):5427-5438.
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Sempio C, Klawitter J, Jackson M, Freni F, Shillingburg R, Hutchison K, Bidwell LC, Christians U, Klawitter J. Analysis of 14 endocannabinoids and endocannabinoid congeners in human plasma using column switching high-performance atmospheric pressure chemical ionization liquid chromatography-mass spectrometry. Anal Bioanal Chem. 2021 May; 413(12):3381-3392.
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Yamada E, Takagi R, Moro H, Sudo K, Kato S. Saliva as a potential matrix for evaluating pharmacologically active dolutegravir concentration in plasma. PLoS One. 2021; 16(2):e0246994.
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