Pentachlorophenol
"Pentachlorophenol" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An insecticide and herbicide that has also been used as a wood preservative. Pentachlorphenol is a widespread environmental pollutant. Both chronic and acute pentachlorophenol poisoning are medical concerns. The range of its biological actions is still being actively explored, but it is clearly a potent enzyme inhibitor and has been used as such as an experimental tool.
Descriptor ID |
D010416
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MeSH Number(s) |
D02.455.426.559.389.657.190.633
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Pentachlorophenol".
Below are MeSH descriptors whose meaning is more specific than "Pentachlorophenol".
This graph shows the total number of publications written about "Pentachlorophenol" by people in this website by year, and whether "Pentachlorophenol" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1997 | 1 | 0 | 1 | 1999 | 1 | 0 | 1 | 2000 | 2 | 0 | 2 | 2002 | 2 | 0 | 2 | 2003 | 3 | 0 | 3 | 2004 | 1 | 0 | 1 | 2005 | 2 | 0 | 2 | 2011 | 1 | 0 | 1 | 2012 | 1 | 0 | 1 | 2013 | 1 | 0 | 1 | 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Pentachlorophenol" by people in Profiles.
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Rudolph J, Erbse AH, Behlen LS, Copley SD. A radical intermediate in the conversion of pentachlorophenol to tetrachlorohydroquinone by Sphingobium chlorophenolicum. Biochemistry. 2014 Oct 21; 53(41):6539-49.
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Yadid I, Rudolph J, Hlouchova K, Copley SD. Sequestration of a highly reactive intermediate in an evolving pathway for degradation of pentachlorophenol. Proc Natl Acad Sci U S A. 2013 Jun 11; 110(24):E2182-90.
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Hlouchova K, Rudolph J, Pietari JM, Behlen LS, Copley SD. Pentachlorophenol hydroxylase, a poorly functioning enzyme required for degradation of pentachlorophenol by Sphingobium chlorophenolicum. Biochemistry. 2012 May 08; 51(18):3848-60.
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Copley SD, Rokicki J, Turner P, Daligault H, Nolan M, Land M. The whole genome sequence of Sphingobium chlorophenolicum L-1: insights into the evolution of the pentachlorophenol degradation pathway. Genome Biol Evol. 2012; 4(2):184-98.
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Bielefeldt AR, Cort T. Dual substrate biodegradation of a nonionic surfactant and pentachlorophenol by Sphingomonas chlorophenolica RA2. Biotechnol Bioeng. 2005 Mar 20; 89(6):680-9.
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Park SK, Bielefeldt AR. Non-ionic surfactant flushing of pentachlorophenol from NAPL-contaminated soil. Water Res. 2005 Apr; 39(7):1388-96.
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Dai M, Copley SD. Genome shuffling improves degradation of the anthropogenic pesticide pentachlorophenol by Sphingobium chlorophenolicum ATCC 39723. Appl Environ Microbiol. 2004 Apr; 70(4):2391-7.
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Park SK, Bielefeldt AR. Aqueous chemistry and interactive effects on non-ionic surfactant and pentachlorophenol sorption to soil. Water Res. 2003 Nov; 37(19):4663-72.
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Park SK, Bielefeldt AR. Equilibrium partitioning of a non-ionic surfactant and pentachlorophenol between water and a non-aqueous phase liquid. Water Res. 2003 Aug; 37(14):3412-20.
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Dai M, Rogers JB, Warner JR, Copley SD. A previously unrecognized step in pentachlorophenol degradation in Sphingobium chlorophenolicum is catalyzed by tetrachlorobenzoquinone reductase (PcpD). J Bacteriol. 2003 Jan; 185(1):302-10.
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