Monoclonal Gammopathy of Undetermined Significance
"Monoclonal Gammopathy of Undetermined Significance" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Conditions characterized by the presence of M protein (Monoclonal protein) in serum or urine without clinical manifestations of plasma cell dyscrasia.
| Descriptor ID |
D008998
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| MeSH Number(s) |
C15.378.147.542.640 C15.378.147.780.570 C20.683.460.640 C20.683.780.640
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| Concept/Terms |
Monoclonal Gammopathy of Undetermined Significance- Monoclonal Gammopathy of Undetermined Significance
- Monoclonal Gammopathies, Benign
- Monoclonal Gammapathy of Undetermined Significance
- Benign Monoclonal Gammopathies
- Benign Monoclonal Gammopathy
- Monoclonal Gammopathy, Benign
- Monoclonal Gammapathies, Benign
- Benign Monoclonal Gammapathies
- Benign Monoclonal Gammapathy
- Monoclonal Gammapathy, Benign
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Below are MeSH descriptors whose meaning is more general than "Monoclonal Gammopathy of Undetermined Significance".
Below are MeSH descriptors whose meaning is more specific than "Monoclonal Gammopathy of Undetermined Significance".
This graph shows the total number of publications written about "Monoclonal Gammopathy of Undetermined Significance" by people in this website by year, and whether "Monoclonal Gammopathy of Undetermined Significance" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
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| 2014 | 1 | 0 | 1 | | 2017 | 1 | 1 | 2 | | 2018 | 1 | 0 | 1 | | 2021 | 2 | 0 | 2 | | 2022 | 1 | 0 | 1 | | 2023 | 1 | 0 | 1 | | 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Monoclonal Gammopathy of Undetermined Significance" by people in Profiles.
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Moreno DF, Nadeu F, Brasó-Maristany F, Vaqué S, Paz S, Mañé J, Cardús O, Medina E, Lozano E, Rodríguez-Lobato LG, de Daniel A, Tovar N, Cibeira MT, Bladé J, Rosiñol L, Prat A, Colomer D, Fernández de Larrea C. Genomic and immune profiling of prognostic risk groups in IgM gammopathy reveals novel biomarkers beyond MYD88 L265P. Front Immunol. 2025; 16:1604089.
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Moreno DF, Fern?ndez de Larrea C. Clinical Implications of Genomic Profile in Waldenstr?m Macroglobulinemia. Hematol Oncol Clin North Am. 2023 08; 37(4):659-670.
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Moreno DF, L?pez-Guerra M, Paz S, Oliver-Cald?s A, Mena MP, Correa JG, Battram AM, Osuna M, Rivas-Delgado A, Rodr?guez-Lobato LG, Card?s O, Tovar N, Cibeira MT, Jim?nez-Segura R, Blad? J, Rosi?ol L, Colomer D, Fern?ndez de Larrea C. Prognostic impact of MYD88 and CXCR4 mutations assessed by droplet digital polymerase chain reaction in IgM monoclonal gammopathy of undetermined significance and smouldering Waldenstr?m macroglobulinaemia. Br J Haematol. 2023 01; 200(2):187-196.
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Isola I, Bras?-Maristany F, Moreno DF, Mena MP, Oliver-Calders A, Par? L, Rodr?guez-Lobato LG, Martin-Antonio B, Cibeira MT, Blad? J, Rosi?ol L, Prat A, Lozano E, Fern?ndez de Larrea C. Gene Expression Analysis of the Bone Marrow Microenvironment Reveals Distinct Immunotypes in Smoldering Multiple Myeloma Associated to Progression to Symptomatic Disease. Front Immunol. 2021; 12:792609.
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Oben B, Froyen G, Maclachlan KH, Leongamornlert D, Abascal F, Zheng-Lin B, Yellapantula V, Derkach A, Geerdens E, Diamond BT, Arijs I, Maes B, Vanhees K, Hultcrantz M, Manasanch EE, Kazandjian D, Lesokhin A, Dogan A, Zhang Y, Mikulasova A, Walker B, Morgan G, Campbell PJ, Landgren O, Rummens JL, Bolli N, Maura F. Whole-genome sequencing reveals progressive versus stable myeloma precursor conditions as two distinct entities. Nat Commun. 2021 03 25; 12(1):1861.
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Dutta AK, Fink JL, Grady JP, Morgan GJ, Mullighan CG, To LB, Hewett DR, Zannettino ACW. Subclonal evolution in disease progression from MGUS/SMM to multiple myeloma is characterised by clonal stability. Leukemia. 2019 02; 33(2):457-468.
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Campbell JP, Heaney JLJ, Pandya S, Afzal Z, Kaiser M, Owen R, Child JA, Cairns DA, Gregory W, Morgan GJ, Jackson GH, Bunce CM, Drayson MT. Response comparison of multiple myeloma and monoclonal gammopathy of undetermined significance to the same anti-myeloma therapy: a retrospective cohort study. Lancet Haematol. 2017 Dec; 4(12):e584-e594.
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Campbell JP, Heaney JLJ, Pandya S, Afzal Z, Kaiser M, Owen R, Child JA, Gregory W, Morgan GJ, Jackson GH, Bunce CM, Drayson MT. Active multiple myeloma suppresses and typically eliminates coexisting MGUS. Br J Cancer. 2017 Sep 05; 117(6):835-839.
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van de Donk NW, Palumbo A, Johnsen HE, Engelhardt M, Gay F, Gregersen H, Hajek R, Kleber M, Ludwig H, Morgan G, Musto P, Plesner T, Sezer O, Terpos E, Waage A, Zweegman S, Einsele H, Sonneveld P, Lokhorst HM. The clinical relevance and management of monoclonal gammopathy of undetermined significance and related disorders: recommendations from the European Myeloma Network. Haematologica. 2014 Jun; 99(6):984-96.
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