Organic Cation Transporter 2
"Organic Cation Transporter 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Organic cation transporter consisting of twelve transmembrane domains and expressed primarily in the kidney. It transports a wide range of metabolites, drugs, and neurotransmitters from the blood to the KIDNEY TUBULES, including DOPAMINE; SEROTONIN; CHOLINE; and CISPLATIN.
Descriptor ID |
D000075102
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MeSH Number(s) |
D12.776.157.530.450.250.812.625 D12.776.157.530.937.612.625 D12.776.543.585.450.250.812.625 D12.776.543.585.937.701.625
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Organic Cation Transporter 2".
Below are MeSH descriptors whose meaning is more specific than "Organic Cation Transporter 2".
This graph shows the total number of publications written about "Organic Cation Transporter 2" by people in this website by year, and whether "Organic Cation Transporter 2" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2016 | 0 | 1 | 1 | 2017 | 0 | 2 | 2 |
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Below are the most recent publications written about "Organic Cation Transporter 2" by people in Profiles.
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Chang C, Hu Y, Hogan SL, Mercke N, Gomez M, O'Bryant C, Bowles DW, George B, Wen X, Aleksunes LM, Joy MS. Pharmacogenomic Variants May Influence the Urinary Excretion of Novel Kidney Injury Biomarkers in Patients Receiving Cisplatin. Int J Mol Sci. 2017 Jun 22; 18(7).
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Checkley LA, Rudolph MC, Wellberg EA, Giles ED, Wahdan-Alaswad RS, Houck JA, Edgerton SM, Thor AD, Schedin P, Anderson SM, MacLean PS. Metformin Accumulation Correlates with Organic Cation Transporter 2 Protein Expression and Predicts Mammary Tumor Regression In Vivo. Cancer Prev Res (Phila). 2017 Mar; 10(3):198-207.
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Yin L, Xu J, Li M, Reddy V, Zhou Q, Liu H, Chu P, Zhang Q, Huang Q, Gao Z, Liang X, Wang HY, Pan Z. Oct2 and Bob1 are sensitive and specific markers in lineage determination of B cell lymphomas with no expression of conventional B cell markers. Histopathology. 2016 Nov; 69(5):775-783.
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Chiba S, Ikawa T, Takeshita H, Kanno S, Nagai T, Takada M, Mukai T, Wempe MF. Human organic cation transporter 2 (hOCT2): Inhibitor studies using S2-hOCT2 cells. Toxicology. 2013 Aug 09; 310:98-103.
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Stellmer F, Keyser B, Burckhardt BC, Koepsell H, Streichert T, Glatzel M, Jabs S, Thiem J, Herdering W, Koeller DM, Goodman SI, Lukacs Z, Ullrich K, Burckhardt G, Braulke T, M?hlhausen C. 3-Hydroxyglutaric acid is transported via the sodium-dependent dicarboxylate transporter NaDC3. J Mol Med (Berl). 2007 Jul; 85(7):763-70.
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Cioffi CC, Pollenz RS, Middleton DL, Wilson MR, Miller NW, William Clem L, Warr GW, Ross DA. Oct2 transcription factor of a teleost fish: activation domains and function from an enhancer. Arch Biochem Biophys. 2002 Aug 01; 404(1):55-61.
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