Claudin-3
"Claudin-3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitously-expressed claudin subtype that acts as a general barrier-forming protein in TIGHT JUNCTIONS. Elevated expression of claudin-3 is found in a variety of tumor cell types, suggesting its role as a therapeutic target for specific ANTINEOPLASTIC AGENTS.
| Descriptor ID |
D062465
|
| MeSH Number(s) |
D12.776.543.940.200.300
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Claudin-3".
Below are MeSH descriptors whose meaning is more specific than "Claudin-3".
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Below are the most recent publications written about "Claudin-3" by people in Profiles.
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Baumgartner HK, Beeman N, Hodges RS, Neville MC. A D-peptide analog of the second extracellular loop of claudin-3 and -4 leads to mislocalized claudin and cellular apoptosis in mammary epithelial cells. Chem Biol Drug Des. 2011 Feb; 77(2):124-36.