 Signaling Lymphocytic Activation Molecule Family Member 1
"Signaling Lymphocytic Activation Molecule Family Member 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 70-kDa SLAM family receptor that consists of an extracellular IMMUNOGLOBULIN-LIKE DOMAIN and an IMMUNOGLOBULIN C2-SET DOMAIN. It is expressed primarily by THYMOCYTES and activated T-LYMPHOCYTES, as well as by MACROPHAGES and DENDRITIC CELLS. It binds SLAMF1 receptors on other cells to mediate T-cell maturation and proliferation. It is also a receptor for the MEASLES VIRUS.
| Descriptor ID |
D000071177
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| MeSH Number(s) |
D12.776.395.550.736.500 D12.776.543.550.746.500 D12.776.543.750.705.970.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Signaling Lymphocytic Activation Molecule Family Member 1".
Below are MeSH descriptors whose meaning is more specific than "Signaling Lymphocytic Activation Molecule Family Member 1".
This graph shows the total number of publications written about "Signaling Lymphocytic Activation Molecule Family Member 1" by people in this website by year, and whether "Signaling Lymphocytic Activation Molecule Family Member 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 |
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Below are the most recent publications written about "Signaling Lymphocytic Activation Molecule Family Member 1" by people in Profiles.
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Kent DG, Copley MR, Benz C, W?hrer S, Dykstra BJ, Ma E, Cheyne J, Zhao Y, Bowie MB, Zhao Y, Gasparetto M, Delaney A, Smith C, Marra M, Eaves CJ. Prospective isolation and molecular characterization of hematopoietic stem cells with durable self-renewal potential. Blood. 2009 Jun 18; 113(25):6342-50.
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