ETS Motif
"ETS Motif" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A helix-turn-helix motif characterized by three alpha-helices and four-stranded beta-sheets arranged in the order alpha1-beta1-beta2-alpha2-alpha3-beta3-beta4. The third alpha-helix contacts the major groove of DNA. The ETS motif and the flanking amino acid sequences of Ets proteins influence the binding affinity, and the alteration of a single amino acid in the Ets domain can change its DNA binding specificity.
| Descriptor ID |
D000071419
|
| MeSH Number(s) |
G02.111.570.820.709.275.500.360.360.500
|
| Concept/Terms |
ETS Motif- ETS Motif
- ETS Motifs
- Helix-Turn-Helix, ETS-Type Domain Containing
- Helix Turn Helix, ETS Type Domain Containing
- ETS Domain
- ETS Domains
|
Below are MeSH descriptors whose meaning is more general than "ETS Motif".
Below are MeSH descriptors whose meaning is more specific than "ETS Motif".
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