 Keratin-10
"Keratin-10" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A type I keratin that is found associated with the KERATIN-1 in terminally differentiated epidermal cells such as those that form the stratum corneum. Mutations in the genes that encode keratin-10 have been associated with HYPERKERATOSIS, EPIDERMOLYTIC.
| Descriptor ID |
D053550
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| MeSH Number(s) |
D05.750.078.593.450.300.100 D12.776.220.475.450.300.100 D12.776.860.607.300.100
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Keratin-10".
Below are MeSH descriptors whose meaning is more specific than "Keratin-10".
This graph shows the total number of publications written about "Keratin-10" by people in this website by year, and whether "Keratin-10" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 | | 2001 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2006 | 1 | 0 | 1 | | 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Keratin-10" by people in Profiles.
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Rice RH, Durbin-Johnson BP, Ishitsuka Y, Salemi M, Phinney BS, Rocke DM, Roop DR. Proteomic Analysis of Loricrin Knockout Mouse Epidermis. J Proteome Res. 2016 08 05; 15(8):2560-6.
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Bjerke GA, Pietrzak K, Melhuish TA, Frierson HF, Paschal BM, Wotton D. Prostate cancer induced by loss of Apc is restrained by TGF? signaling. PLoS One. 2014; 9(3):e92800.
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Gallant-Behm CL, Mustoe TA. Occlusion regulates epidermal cytokine production and inhibits scar formation. Wound Repair Regen. 2010 Mar-Apr; 18(2):235-44.
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Chen J, Cheng X, Merched-Sauvage M, Caulin C, Roop DR, Koch PJ. An unexpected role for keratin 10 end domains in susceptibility to skin cancer. J Cell Sci. 2006 Dec 15; 119(Pt 24):5067-76.
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Xu X, Kawachi Y, Nakamura Y, Sakurai H, Hirota A, Banno T, Takahashi T, Roop DR, Otsuka F. Yin-yang 1 negatively regulates the differentiation-specific transcription of mouse loricrin gene in undifferentiated keratinocytes. J Invest Dermatol. 2004 Dec; 123(6):1120-6.
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Arin MJ, Longley MA, Wang XJ, Roop DR. Focal activation of a mutant allele defines the role of stem cells in mosaic skin disorders. J Cell Biol. 2001 Feb 05; 152(3):645-9.
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Arin MJ, Longley MA, Anton-Lamprecht I, Kurze G, Huber M, Hohl D, Rothnagel JA, Roop DR. A novel substitution in keratin 10 in epidermolytic hyperkeratosis. J Invest Dermatol. 1999 Apr; 112(4):506-8.
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Suga Y, Duncan KO, Heald PW, Roop DR. A novel helix termination mutation in keratin 10 in annular epidermolytic ichthyosis, a variant of bullous congenital ichthyosiform erythroderma. J Invest Dermatol. 1998 Dec; 111(6):1220-3.
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Huber M, Scaletta C, Benathan M, Frenk E, Greenhalgh DA, Rothnagel JA, Roop DR, Hohl D. Abnormal keratin 1 and 10 cytoskeleton in cultured keratinocytes from epidermolytic hyperkeratosis caused by keratin 10 mutations. J Invest Dermatol. 1994 May; 102(5):691-4.
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