 Lab-On-A-Chip Devices
"Lab-On-A-Chip Devices" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Microdevices that combine microfluidics technology with electrical and/or mechanical functions for analyzing very small fluid volumes. They consist of microchannels etched into substrates made of silicon, glass, or polymer using processes similar to photolithography. The test fluids in the channels can then interact with different elements such as electrodes, photodetectors, chemical sensors, pumps, and valves.
| Descriptor ID |
D056656
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| MeSH Number(s) |
E07.305.343.500
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| Concept/Terms |
Lab-On-A-Chip Devices- Lab-On-A-Chip Devices
- Device, Lab-On-A-Chip
- Devices, Lab-On-A-Chip
- Lab On A Chip Devices
- Lab-On-A-Chip Device
Microchip Analytical Devices- Microchip Analytical Devices
- Analytical Device, Microchip
- Analytical Devices, Microchip
- Device, Microchip Analytical
- Devices, Microchip Analytical
- Microchip Analytical Device
- Microfluidic Lab-On-A-Chip
- Lab-On-A-Chip, Microfluidic
- Lab-On-A-Chips, Microfluidic
- Microfluidic Lab On A Chip
- Microfluidic Lab-On-A-Chips
- Microfluidic Devices
- Device, Microfluidic
- Devices, Microfluidic
- Microfluidic Device
- Microfluidic Microchips
- Microchip, Microfluidic
- Microchips, Microfluidic
- Microfluidic Microchip
Nanochip Analytical Devices- Nanochip Analytical Devices
- Analytical Device, Nanochip
- Analytical Devices, Nanochip
- Device, Nanochip Analytical
- Devices, Nanochip Analytical
- Nanochip Analytical Device
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Below are MeSH descriptors whose meaning is more general than "Lab-On-A-Chip Devices".
Below are MeSH descriptors whose meaning is more specific than "Lab-On-A-Chip Devices".
This graph shows the total number of publications written about "Lab-On-A-Chip Devices" by people in this website by year, and whether "Lab-On-A-Chip Devices" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 | | 2009 | 1 | 0 | 1 | | 2010 | 0 | 1 | 1 | | 2015 | 4 | 2 | 6 | | 2016 | 3 | 1 | 4 | | 2017 | 1 | 1 | 2 | | 2018 | 2 | 3 | 5 | | 2019 | 1 | 0 | 1 | | 2020 | 1 | 2 | 3 | | 2021 | 2 | 4 | 6 | | 2023 | 0 | 1 | 1 | | 2024 | 1 | 4 | 5 | | 2025 | 3 | 1 | 4 | | 2026 | 2 | 1 | 3 |
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Below are the most recent publications written about "Lab-On-A-Chip Devices" by people in Profiles.
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Zlotnick HM, Goddard DN, Calo CJ, Dhand AP, Davidson MD, Solsona-Pujol A, Makhoul JT, Weppner HK, Wong M, Scanzello CR, Hind LE, Burdick JA. Synovial fibroblasts modulate endothelial activation in an acute injury-on-a-chip model. Proc Natl Acad Sci U S A. 2026 May 19; 123(20):e2524677123.
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Akh L, Fajrial AK, Sohn S, Seelbinder B, Xu X, Tan W, Slansky JE, Neu CP, Ding X. Vector-free DNA transfection by nuclear envelope mechanoporation. Lab Chip. 2026 May 05; 26(9):2673-2683.
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Owens JM, Weppner HK, Ignes-Romeu A, Burleson JW, Hind LE. Interleukin-6 regulates the neutrophil response to diverse bacteria. Front Immunol. 2026; 17:1783843.
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Hanna AR, Shepherd SJ, Datto GA, El-Mayta R, Anderson T, Navarro IB, Ricciardi AS, Padilla MS, Srikumar N, Zhang S, Yamagata HM, Meng NY, Buser JR, Alameh MG, Mitchell MJ, Issadore DA. Automated and Parallelized Microfluidic Generation of Large and Precisely Defined Lipid Nanoparticle Libraries. ACS Nano. 2026 Jan 13; 20(1):772-789.
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Zlotnick HM, Goddard DN, Burdick JA. Evaluating Complexity in Orthopedic Tissue-on-a-Chip Systems. Adv Healthc Mater. 2026 Mar; 15(9):e04275.
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Ibrahim M, Moinuddin SM, Hossain MS, Nguyen T, Sarkar T, El-Shamy A, Cucullo L, Lahm T, Nozik E, Simon MA, Stenmark KR, Ahsan F. Image cytometry-based quantification protocol of human pulmonary arterial endothelial cells in lab-fabricated multichannel microfluidic devices. STAR Protoc. 2025 Dec 19; 6(4):104147.
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Ma C, Wang H, Liu L, Chen R, Mukherjee N, Tong J, Kazmi S, Fang X, Witkowski MT, Aifantis I, Ghassemi S, Chen W. Bioengineered immunocompetent preclinical trial-on-chip tool enables screening of CAR T cell therapy for leukaemia. Nat Biomed Eng. 2025 Dec; 9(12):2098-2114.
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Mossburg KJ, Shepherd SJ, Barragan D, O NH, Berkow EK, Maidment PSN, Rosario Berrios DN, Hsu JC, Siedlik MJ, Yadavali S, Mitchell MJ, Issadore D, Cormode DP. Towards the clinical translation of a silver sulfide nanoparticle contrast agent: large scale production with a highly parallelized microfluidic chip. Eur J Nucl Med Mol Imaging. 2025 Feb; 52(3):1177-1188.
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Mora-Boza A, Mulero-Russe A, Di Caprio N, Burdick JA, O'Neill E, Singh A, García AJ. Facile photopatterning of perfusable microchannels in hydrogels for microphysiological systems. Nat Protoc. 2025 01; 20(1):272-292.
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Palanki R, Han EL, Murray AM, Maganti R, Tang S, Swingle KL, Kim D, Yamagata H, Safford HC, Mrksich K, Peranteau WH, Mitchell MJ. Optimized microfluidic formulation and organic excipients for improved lipid nanoparticle mediated genome editing. Lab Chip. 2024 08 06; 24(16):3790-3801.
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