 GTP-Binding Protein gamma Subunits
"GTP-Binding Protein gamma Subunits" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Heterotrimeric GTP-binding protein subunits that tightly associate with GTP-BINDING PROTEIN BETA SUBUNITS. A dimer of beta and gamma subunits is formed when the GTP-BINDING PROTEIN ALPHA SUBUNIT dissociates from the GTP-binding protein heterotrimeric complex. The beta-gamma dimer can play an important role in signal transduction by interacting with a variety of second messengers.
| Descriptor ID |
D044388
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| MeSH Number(s) |
D12.644.360.360.730 D12.776.157.325.332.730 D12.776.476.375.730 D12.776.543.325.625
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| Concept/Terms |
GTP-Binding Protein gamma Subunits- GTP-Binding Protein gamma Subunits
- GTP Binding Protein gamma Subunits
- G-Protein gamma Subunit
- G Protein gamma Subunit
- Subunit, G-Protein gamma
- gamma Subunit, G-Protein
- GTP-Binding Protein gamma Subunit
- GTP Binding Protein gamma Subunit
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Below are MeSH descriptors whose meaning is more general than "GTP-Binding Protein gamma Subunits".
Below are MeSH descriptors whose meaning is more specific than "GTP-Binding Protein gamma Subunits".
This graph shows the total number of publications written about "GTP-Binding Protein gamma Subunits" by people in this website by year, and whether "GTP-Binding Protein gamma Subunits" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
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| 2010 | 1 | 0 | 1 | | 2012 | 1 | 0 | 1 | | 2013 | 1 | 1 | 2 | | 2015 | 2 | 0 | 2 | | 2016 | 1 | 0 | 1 | | 2017 | 1 | 0 | 1 | | 2018 | 1 | 0 | 1 | | 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "GTP-Binding Protein gamma Subunits" by people in Profiles.
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Khan SM, Martin RD, Bayne A, Pétrin D, Bourque K, Jones-Tabah J, Bouazza C, Blaney J, Lau J, Martins-Cannavino K, Gora S, Zhang A, MacKinnon S, Trieu P, Clarke PBS, Trempe JF, Tanny JC, Hébert TE. Gß? subunits colocalize with RNA polymerase II and regulate transcription in cardiac fibroblasts. J Biol Chem. 2023 04; 299(4):103064.
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Gulati S, Jin H, Masuho I, Orban T, Cai Y, Pardon E, Martemyanov KA, Kiser PD, Stewart PL, Ford CP, Steyaert J, Palczewski K. Targeting G protein-coupled receptor signaling at the G protein level with a selective nanobody inhibitor. Nat Commun. 2018 05 18; 9(1):1996.
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Paudyal P, Xie Q, Vaddi PK, Henry MD, Chen S. Inhibiting G protein ß? signaling blocks prostate cancer progression and enhances the efficacy of paclitaxel. Oncotarget. 2017 May 30; 8(22):36067-36081.
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Kamal FA, Travers JG, Schafer AE, Ma Q, Devarajan P, Blaxall BC. G Protein-Coupled Receptor-G-Protein ß?-Subunit Signaling Mediates Renal Dysfunction and Fibrosis in Heart Failure. J Am Soc Nephrol. 2017 Jan; 28(1):197-208.
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Stojic L, Niemczyk M, Orjalo A, Ito Y, Ruijter AE, Uribe-Lewis S, Joseph N, Weston S, Menon S, Odom DT, Rinn J, Gergely F, Murrell A. Transcriptional silencing of long noncoding RNA GNG12-AS1 uncouples its transcriptional and product-related functions. Nat Commun. 2016 Feb 02; 7:10406.
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Khan SM, Min A, Gora S, Houranieh GM, Campden R, Robitaille M, Trieu P, Pétrin D, Jacobi AM, Behlke MA, Angers S, Hébert TE. Gß4?1 as a modulator of M3 muscarinic receptor signalling and novel roles of Gß1 subunits in the modulation of cellular signalling. Cell Signal. 2015 Aug; 27(8):1597-608.
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Campden R, Pétrin D, Robitaille M, Audet N, Gora S, Angers S, Hébert TE. Tandem affinity purification to identify cytosolic and nuclear gß?-interacting proteins. Methods Mol Biol. 2015; 1234:161-84.
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Li F, Ponissery-Saidu S, Yee KK, Wang H, Chen ML, Iguchi N, Zhang G, Jiang P, Reisert J, Huang L. Heterotrimeric G protein subunit G?13 is critical to olfaction. J Neurosci. 2013 May 01; 33(18):7975-84.
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Khan SM, Sleno R, Gora S, Zylbergold P, Laverdure JP, Labbé JC, Miller GJ, Hébert TE. The expanding roles of Gß? subunits in G protein-coupled receptor signaling and drug action. Pharmacol Rev. 2013 Apr; 65(2):545-77.
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Loo L, Shepherd AJ, Mickle AD, Lorca RA, Shutov LP, Usachev YM, Mohapatra DP. The C-type natriuretic peptide induces thermal hyperalgesia through a noncanonical Gß?-dependent modulation of TRPV1 channel. J Neurosci. 2012 Aug 29; 32(35):11942-55.
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