 Lethal Dose 50
"Lethal Dose 50" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The dose amount of poisonous or toxic substance or dose of ionizing radiation required to kill 50% of the tested population.
| Descriptor ID |
D007928
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| MeSH Number(s) |
E05.940.402 G07.225.500 G07.690.773.875.750 G07.690.936.500.750
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Lethal Dose 50".
Below are MeSH descriptors whose meaning is more specific than "Lethal Dose 50".
This graph shows the total number of publications written about "Lethal Dose 50" by people in this website by year, and whether "Lethal Dose 50" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 2 | 2 | | 1999 | 0 | 1 | 1 | | 2002 | 0 | 2 | 2 | | 2004 | 0 | 1 | 1 | | 2008 | 0 | 1 | 1 | | 2014 | 0 | 1 | 1 | | 2015 | 0 | 1 | 1 | | 2018 | 0 | 1 | 1 | | 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "Lethal Dose 50" by people in Profiles.
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Borja M, Casta?eda-Gayt?n G, Alag?n A, Strickland JL, Parkinson CL, Guti?rrez-Mart?nez A, Rodriguez-L?pez B, Zarzosa V, Lomonte B, Saviola AJ, Fern?ndez J, Smith CF, Hansen KC, P?rez-Robles A, Casta?eda-P?rez S, Hirst SR, Olvera-Rodr?guez F, Fern?ndez-Badillo L, Sigala J, Jones J, Monta?o-Ruvalcaba C, Ram?rez-Chaparro R, Margres MJ, Acosta-Campa?a G, Neri-Castro E. Venom variation and ontogenetic changes in the Crotalus molossus complex: Insights into composition, activities, and antivenom neutralization. Comp Biochem Physiol C Toxicol Pharmacol. 2025 Apr; 290:110129.
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Mackessy SP, Leroy J, Moci?o-Deloya E, Setser K, Bryson RW, Saviola AJ. Venom Ontogeny in the Mexican Lance-Headed Rattlesnake (Crotalus polystictus). Toxins (Basel). 2018 07 03; 10(7).
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LaFonte BE, Raffel TR, Monk IN, Johnson PT. Quantifying larval trematode infections in hosts: A comparison of method validity and implications for infection success. Exp Parasitol. 2015 Jul; 154:155-62.
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Guzman ML, Yang N, Sharma KK, Balys M, Corbett CA, Jordan CT, Becker MW, Steidl U, Abdel-Wahab O, Levine RL, Marcucci G, Roboz GJ, Hassane DC. Selective activity of the histone deacetylase inhibitor AR-42 against leukemia stem cells: a novel potential strategy in acute myelogenous leukemia. Mol Cancer Ther. 2014 Aug; 13(8):1979-90.
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Nanayakkara NP, Tekwani BL, Herath HM, Sahu R, Gettayacamin M, Tungtaeng A, van Gessel Y, Baresel P, Wickham KS, Bartlett MS, Fronczek FR, Melendez V, Ohrt C, Reichard GA, McChesney JD, Rochford R, Walker LA. Scalable preparation and differential pharmacologic and toxicologic profiles of primaquine enantiomers. Antimicrob Agents Chemother. 2014 Aug; 58(8):4737-44.
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Wyckoff AC, Lockwood KL, Meyerett-Reid C, Michel BA, Bender H, VerCauteren KC, Zabel MD. Estimating prion adsorption capacity of soil by BioAssay of Subtracted Infectivity from Complex Solutions (BASICS). PLoS One. 2013; 8(3):e58630.
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Gat O, Galen JE, Tennant S, Simon R, Blackwelder WC, Silverman DJ, Pasetti MF, Levine MM. Cell-associated flagella enhance the protection conferred by mucosally-administered attenuated Salmonella Paratyphi A vaccines. PLoS Negl Trop Dis. 2011 Nov; 5(11):e1373.
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Wilson JW, Ott CM, Quick L, Davis R, H?ner zu Bentrup K, Crabb? A, Richter E, Sarker S, Barrila J, Porwollik S, Cheng P, McClelland M, Tsaprailis G, Radabaugh T, Hunt A, Shah M, Nelman-Gonzalez M, Hing S, Parra M, Dumars P, Norwood K, Bober R, Devich J, Ruggles A, CdeBaca A, Narayan S, Benjamin J, Goulart C, Rupert M, Catella L, Schurr MJ, Buchanan K, Morici L, McCracken J, Porter MD, Pierson DL, Smith SM, Mergeay M, Leys N, Stefanyshyn-Piper HM, Gorie D, Nickerson CA. Media ion composition controls regulatory and virulence response of Salmonella in spaceflight. PLoS One. 2008; 3(12):e3923.
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Borovsky D, Meola SM. Biochemical and cytoimmunological evidence for the control of Aedes aegypti larval trypsin with Aea-TMOF. Arch Insect Biochem Physiol. 2004 Mar; 55(3):124-39.
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Mann MA, Tyler KL, Knipe DM, Fields BN. Type 3 reovirus neuroinvasion after intramuscular inoculation: viral genetic determinants of lethality and spinal cord infection. Virology. 2002 Nov 25; 303(2):213-21.
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