 Methylcholanthrene
"Methylcholanthrene" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A carcinogen that is often used in experimental cancer studies.
| Descriptor ID |
D008748
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| MeSH Number(s) |
D02.455.426.559.847.149.500 D04.615.149.500
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| Concept/Terms |
3-Methylcholanthrene- 3-Methylcholanthrene
- 3 Methylcholanthrene
- 20-Methylcholanthrene
- 20 Methylcholanthrene
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Below are MeSH descriptors whose meaning is more general than "Methylcholanthrene".
Below are MeSH descriptors whose meaning is more specific than "Methylcholanthrene".
This graph shows the total number of publications written about "Methylcholanthrene" by people in this website by year, and whether "Methylcholanthrene" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 | | 2002 | 0 | 2 | 2 | | 2006 | 2 | 1 | 3 | | 2007 | 0 | 1 | 1 | | 2009 | 1 | 0 | 1 | | 2010 | 0 | 1 | 1 | | 2012 | 0 | 1 | 1 | | 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Methylcholanthrene" by people in Profiles.
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Bauer AK, Dwyer-Nield LD. Two-stage 3-methylcholanthrene and butylated hydroxytoluene-induced lung carcinogenesis in mice. Methods Cell Biol. 2021; 163:153-173.
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Karoor V, Le M, Merrick D, Fagan KA, Dempsey EC, Miller YE. Alveolar hypoxia promotes murine lung tumor growth through a VEGFR-2/EGFR-dependent mechanism. Cancer Prev Res (Phila). 2012 Aug; 5(8):1061-71.
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Rondini EA, Walters DM, Bauer AK. Vanadium pentoxide induces pulmonary inflammation and tumor promotion in a strain-dependent manner. Part Fibre Toxicol. 2010 Apr 12; 7:9.
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Elkabets M, Krelin Y, Dotan S, Cerwenka A, Porgador A, Lichtenstein RG, White MR, Zoller M, Iwakura Y, Dinarello CA, Voronov E, Apte RN. Host-derived interleukin-1alpha is important in determining the immunogenicity of 3-methylcholantrene tumor cells. J Immunol. 2009 Apr 15; 182(8):4874-81.
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Krelin Y, Voronov E, Dotan S, Elkabets M, Reich E, Fogel M, Huszar M, Iwakura Y, Segal S, Dinarello CA, Apte RN. Interleukin-1beta-driven inflammation promotes the development and invasiveness of chemical carcinogen-induced tumors. Cancer Res. 2007 Feb 01; 67(3):1062-71.
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Reisdorph R, Lindahl R. Constitutive and 3-methylcholanthrene-induced rat ALDH3A1 expression is mediated by multiple xenobiotic response elements. Drug Metab Dispos. 2007 Mar; 35(3):386-93.
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Keith RL, Geraci MW, Nana-Sinkam SP, Breyer RM, Hudish TM, Meyer AM, Malkinson AM, Dwyer-Nield LD. Prostaglandin E2 receptor subtype 2 (EP2) null mice are protected against murine lung tumorigenesis. Anticancer Res. 2006 Jul-Aug; 26(4B):2857-61.
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Anderson GR, Hasan A, Yin H, Qadri I, Quattrochi LC. Regulation of the CYP1A1 gene by 2,3,7,8-tetrachlorodibenzo-p-dioxin but not by beta-naphthoflavone or 3-methylcholanthrene is altered in hepatitis C virus replicon-expressing cells. Mol Pharmacol. 2006 Sep; 70(3):1062-70.
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Malkinson A, Radcliffe R, Bauer A, Dwyer-Nield L, Kleeberger S. Quantitative trait loci that regulate susceptibility to both butylated hydroxytoluene-induced pulmonary inflammation and lung tumor promotion in CXB recombinant inbred mice. Chest. 2002 Mar; 121(3 Suppl):82S.
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Keith RL, Miller YE, Hoshikawa Y, Moore MD, Gesell TL, Gao B, Malkinson AM, Golpon HA, Nemenoff RA, Geraci MW. Manipulation of pulmonary prostacyclin synthase expression prevents murine lung cancer. Cancer Res. 2002 Feb 01; 62(3):734-40.
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