 Xylazine
"Xylazine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An adrenergic alpha-2 agonist used as a sedative, analgesic and centrally acting muscle relaxant in VETERINARY MEDICINE.
| Descriptor ID |
D014991
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| MeSH Number(s) |
D02.886.665.985 D03.383.855.985
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Xylazine".
Below are MeSH descriptors whose meaning is more specific than "Xylazine".
This graph shows the total number of publications written about "Xylazine" by people in this website by year, and whether "Xylazine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 | | 2007 | 1 | 0 | 1 | | 2011 | 1 | 0 | 1 | | 2023 | 0 | 1 | 1 | | 2024 | 2 | 0 | 2 | | 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Xylazine" by people in Profiles.
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Thakrar AP, Zwiebel SJ, Christine PJ, Spadaro A, Davis MH, Bhatia R, Rohacs N, Xu L, Perrone J, Lowenstein M. Manifestations of potential xylazine withdrawal: A retrospective cohort study with nested case series. Drug Alcohol Depend. 2025 Jul 01; 272:112681.
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Retrouvey H, Meyer MA, Ipaktchi K, Maertens A, Folchert M, Lauder A. Management of Xylazine-Induced Soft-Tissue Necrosis: A Review of 20 Cases. J Am Acad Orthop Surg. 2024 Dec 01; 32(23):e1219-e1225.
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Hoffman GR, Giduturi C, Cordaro NJ, Yoshida CT, Schoffstall AM, Stabio ME, Zuckerman MD. Classics in Chemical Neuroscience: Xylazine. ACS Chem Neurosci. 2024 06 05; 15(11):2091-2098.
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Love JS, Levine M, Aldy K, Brent J, Krotulski AJ, Logan BK, Vargas-Torres C, Walton SE, Amaducci A, Calello D, Hendrickson R, Hughes A, Kurt A, Judge B, Pizon A, Schwarz E, Shulman J, Wiegan T, Wax P, Manini AF. Opioid overdoses involving xylazine in emergency department patients: a multicenter study. Clin Toxicol (Phila). 2023 03; 61(3):173-180.
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Sloan RC, Rosenbaum M, O'Rourke D, Oppelt K, Frasier CR, Waston CA, Allan AG, Brown DA. High doses of ketamine-xylazine anesthesia reduce cardiac ischemia-reperfusion injury in guinea pigs. J Am Assoc Lab Anim Sci. 2011 May; 50(3):349-54.
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Woodward WR, Choi D, Grose J, Malmin B, Hurst S, Pang J, Weleber RG, Pillers DA. Isoflurane is an effective alternative to ketamine/xylazine/acepromazine as an anesthetic agent for the mouse electroretinogram. Doc Ophthalmol. 2007 Nov; 115(3):187-201.
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Lieggi CC, Artwohl JE, Leszczynski JK, Rodriguez NA, Fickbohm BL, Fortman JD. Efficacy and safety of stored and newly prepared tribromoethanol in ICR mice. Contemp Top Lab Anim Sci. 2005 Jan; 44(1):17-22.
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Kisley MA, Gerstein GL. Trial-to-trial variability and state-dependent modulation of auditory-evoked responses in cortex. J Neurosci. 1999 Dec 01; 19(23):10451-60.
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Lockwood LL, Silbert LH, Laudenslager ML, Watkins LR, Maier SF. Anesthesia-induced modulation of in vivo antibody levels: a study of pentobarbital, chloral hydrate, methoxyflurane, halothane, and ketamine/xylazine. Anesth Analg. 1993 Oct; 77(4):769-74.
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Spoerke DG, Hall AH, Grimes MJ, Honea BN, Rumack BH. Human overdose with the veterinary tranquilizer xylazine. Am J Emerg Med. 1986 May; 4(3):222-4.
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