 Milrinone
"Milrinone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A positive inotropic cardiotonic agent with vasodilator properties. It inhibits cAMP phosphodiesterase type 3 activity in myocardium and vascular smooth muscle. Milrinone is a derivative of amrinone and has 20-30 times the inotropic potency of amrinone.
| Descriptor ID |
D020105
|
| MeSH Number(s) |
D02.092.080.085.543 D03.383.725.050.085.543
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Milrinone".
Below are MeSH descriptors whose meaning is more specific than "Milrinone".
This graph shows the total number of publications written about "Milrinone" by people in this website by year, and whether "Milrinone" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 | | 1996 | 0 | 1 | 1 | | 2001 | 2 | 0 | 2 | | 2013 | 1 | 0 | 1 | | 2016 | 2 | 0 | 2 | | 2018 | 1 | 0 | 1 | | 2019 | 1 | 0 | 1 | | 2021 | 1 | 2 | 3 |
To return to the timeline, click here.
Below are the most recent publications written about "Milrinone" by people in Profiles.
-
Kenneally AM, Agbana P, Gardner B, Bae Y, Mitchell T, Beckman EJ. Compatibility of calcium chloride with milrinone, epinephrine, vasopressin, and heparin via in vitro testing and simulated Y-site administration. Am J Health Syst Pharm. 2023 Jan 24; 80(3):164-170.
-
Mandell E, Kinsella JP, Abman SH. Persistent pulmonary hypertension of the newborn. Pediatr Pulmonol. 2021 03; 56(3):661-669.
-
Coleman RD, Chartan CA, Mourani PM. Intensive care management of right ventricular failure and pulmonary hypertension crises. Pediatr Pulmonol. 2021 03; 56(3):636-648.
-
Gist KM, Korst A, Nakano SJ, Stauffer BL, Karimpour-Fard A, Zhou W, Campbell K, Wempe MF, Sucharov CC, Miyamoto SD. Circulating cyclic adenosine monophosphate concentrations in milrinone treated paediatric patients after congenital heart surgery. Cardiol Young. 2021 Sep; 31(9):1393-1400.
-
Hornik CP, Yogev R, Mourani PM, Watt KM, Sullivan JE, Atz AM, Speicher D, Al-Uzri A, Adu-Darko M, Payne EH, Gelber CE, Lin S, Harper B, Melloni C, Cohen-Wolkowiez M, Gonzalez D. Population Pharmacokinetics of Milrinone in Infants, Children, and Adolescents. J Clin Pharmacol. 2019 12; 59(12):1606-1619.
-
Mizuno T, Gist KM, Gao Z, Wempe MF, Alten J, Cooper DS, Goldstein SL, Vinks AA. Developmental Pharmacokinetics and Age-Appropriate Dosing Design of Milrinone in Neonates and Infants with Acute Kidney Injury Following Cardiac Surgery. Clin Pharmacokinet. 2019 06; 58(6):793-803.
-
Gist KM, Cooper DS, Wrona J, Faubel S, Altmann C, Gao Z, Marino BS, Alten J, Hock KM, Mizuno T, Vinks AA, Joy MS, Wempe MF, Bennett MR, Goldstein SL. Acute Kidney Injury Biomarkers Predict an Increase in Serum Milrinone Concentration Earlier Than Serum Creatinine-Defined Acute Kidney Injury in Infants After Cardiac Surgery. Ther Drug Monit. 2018 04; 40(2):186-194.
-
Nakano SJ, Nelson P, Sucharov CC, Miyamoto SD. Myocardial Response to Milrinone in Single Right Ventricle Heart Disease. J Pediatr. 2016 07; 174:199-203.e5.
-
Gist KM, Goldstein SL, Joy MS, Vinks AA. Milrinone Dosing Issues in Critically Ill Children With Kidney Injury: A Review. J Cardiovasc Pharmacol. 2016 Feb; 67(2):175-81.
-
Gist KM, Mizuno T, Goldstein SL, Vinks A. Retrospective Evaluation of Milrinone Pharmacokinetics in Children With Kidney Injury. Ther Drug Monit. 2015 Dec; 37(6):792-6.
|
People  People who have written about this concept. _
Similar Concepts
People who have written about this concept.
_
Top Journals
Top journals in which articles about this concept have been published.
|