 Neurofibroma
"Neurofibroma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A moderately firm, benign, encapsulated tumor resulting from proliferation of SCHWANN CELLS and FIBROBLASTS that includes portions of nerve fibers. The tumors usually develop along peripheral or cranial nerves and are a central feature of NEUROFIBROMATOSIS 1, where they may occur intracranially or involve spinal roots. Pathologic features include fusiform enlargement of the involved nerve. Microscopic examination reveals a disorganized and loose cellular pattern with elongated nuclei intermixed with fibrous strands. (From Adams et al., Principles of Neurology, 6th ed, p1016)
| Descriptor ID |
D009455
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| MeSH Number(s) |
C04.557.580.600.580 C10.551.775.500.750 C10.668.829.725.500.600
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Neurofibroma".
Below are MeSH descriptors whose meaning is more specific than "Neurofibroma".
This graph shows the total number of publications written about "Neurofibroma" by people in this website by year, and whether "Neurofibroma" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 | | 2006 | 1 | 0 | 1 | | 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Neurofibroma" by people in Profiles.
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Banerjee J, Allaway RJ, Taroni JN, Baker A, Zhang X, Moon CI, Pratilas CA, Blakeley JO, Guinney J, Hirbe A, Greene CS, Gosline SJ. Integrative Analysis Identifies Candidate Tumor Microenvironment and Intracellular Signaling Pathways that Define Tumor Heterogeneity in NF1. Genes (Basel). 2020 02 21; 11(2).
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Norbury JW, Boyer PJ. Response to 'A Technical Note for Ultrasound Imaging of the Peripheral Nerve Mass Lesions'. Am J Phys Med Rehabil. 2019 06; 98(6):e62-e63.
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Norbury JW, Guo Y, Boyer PJ, Zeri RS. The Power of Doppler in the Popliteal Fossa: Sonographic Diagnosis of a Fibular Nerve Neurofibroma in a Patient With Posterior Knee Swelling. Am J Phys Med Rehabil. 2018 10; 97(10):e100-e101.
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Sivamani RK, Howe WR, Dellavalle RP. Acute onset of neurofibromas in association with esophageal adenocarcinoma. J Am Acad Dermatol. 2009 May; 60(5):880-1.
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Munchhof AM, Li F, White HA, Mead LE, Krier TR, Fenoglio A, Li X, Yuan J, Yang FC, Ingram DA. Neurofibroma-associated growth factors activate a distinct signaling network to alter the function of neurofibromin-deficient endothelial cells. Hum Mol Genet. 2006 Jun 01; 15(11):1858-69.
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Garg S, Hosalkar H, Dormans JP. Quadriplegia in a 10 year-old boy due to multiple cervical neurofibromas. Spine (Phila Pa 1976). 2003 Sep 01; 28(17):E339-43.
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