 Hydroxymethylglutaryl CoA Reductases
"Hydroxymethylglutaryl CoA Reductases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes that catalyze the reversible reduction of alpha-carboxyl group of 3-hydroxy-3-methylglutaryl-coenzyme A to yield MEVALONIC ACID.
| Descriptor ID |
D006903
|
| MeSH Number(s) |
D08.811.682.047.820.150.415
|
| Concept/Terms |
Hydroxymethylglutaryl CoA Reductases- Hydroxymethylglutaryl CoA Reductases
- Hydroxymethylglutaryl CoA Reductase
- HMG CoA Reductases
- 3-Hydroxy-3-methylglutaryl CoA Reductase
- 3 Hydroxy 3 methylglutaryl CoA Reductase
- CoA Reductase, 3-Hydroxy-3-methylglutaryl
- Reductase, 3-Hydroxy-3-methylglutaryl CoA
- HMG CoA Reductase
|
Below are MeSH descriptors whose meaning is more general than "Hydroxymethylglutaryl CoA Reductases".
Below are MeSH descriptors whose meaning is more specific than "Hydroxymethylglutaryl CoA Reductases".
This graph shows the total number of publications written about "Hydroxymethylglutaryl CoA Reductases" by people in this website by year, and whether "Hydroxymethylglutaryl CoA Reductases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 | | 2002 | 0 | 2 | 2 | | 2004 | 2 | 0 | 2 | | 2006 | 0 | 1 | 1 | | 2009 | 1 | 0 | 1 | | 2014 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Hydroxymethylglutaryl CoA Reductases" by people in Profiles.
-
Swerdlow DI, Preiss D, Kuchenbaecker KB, Holmes MV, Engmann JE, Shah T, Sofat R, Stender S, Johnson PC, Scott RA, Leusink M, Verweij N, Sharp SJ, Guo Y, Giambartolomei C, Chung C, Peasey A, Amuzu A, Li K, Palmen J, Howard P, Cooper JA, Drenos F, Li YR, Lowe G, Gallacher J, Stewart MC, Tzoulaki I, Buxbaum SG, van der A DL, Forouhi NG, Onland-Moret NC, van der Schouw YT, Schnabel RB, Hubacek JA, Kubinova R, Baceviciene M, Tamosiunas A, Pajak A, Topor-Madry R, Stepaniak U, Malyutina S, Baldassarre D, Sennblad B, Tremoli E, de Faire U, Veglia F, Ford I, Jukema JW, Westendorp RG, de Borst GJ, de Jong PA, Algra A, Spiering W, Maitland-van der Zee AH, Klungel OH, de Boer A, Doevendans PA, Eaton CB, Robinson JG, Duggan D, Kjekshus J, Downs JR, Gotto AM, Keech AC, Marchioli R, Tognoni G, Sever PS, Poulter NR, Waters DD, Pedersen TR, Amarenco P, Nakamura H, McMurray JJ, Lewsey JD, Chasman DI, Ridker PM, Maggioni AP, Tavazzi L, Ray KK, Seshasai SR, Manson JE, Price JF, Whincup PH, Morris RW, Lawlor DA, Smith GD, Ben-Shlomo Y, Schreiner PJ, Fornage M, Siscovick DS, Cushman M, Kumari M, Wareham NJ, Verschuren WM, Redline S, Patel SR, Whittaker JC, Hamsten A, Delaney JA, Dale C, Gaunt TR, Wong A, Kuh D, Hardy R, Kathiresan S, Castillo BA, van der Harst P, Brunner EJ, Tybjaerg-Hansen A, Marmot MG, Krauss RM, Tsai M, Coresh J, Hoogeveen RC, Psaty BM, Lange LA, Hakonarson H, Dudbridge F, Humphries SE, Talmud PJ, Kivim?ki M, Timpson NJ, Langenberg C, Asselbergs FW, Voevoda M, Bobak M, Pikhart H, Wilson JG, Reiner AP, Keating BJ, Hingorani AD, Sattar N. HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials. Lancet. 2015 Jan 24; 385(9965):351-61.
-
Faulkner RA, Nguyen AD, Jo Y, DeBose-Boyd RA. Lipid-regulated degradation of HMG-CoA reductase and Insig-1 through distinct mechanisms in insect cells. J Lipid Res. 2013 Apr; 54(4):1011-22.
-
Charlton-Menys V, Betteridge DJ, Colhoun H, Fuller J, France M, Hitman GA, Livingstone SJ, Neil HA, Newman CB, Szarek M, DeMicco DA, Durrington PN. Targets of statin therapy: LDL cholesterol, non-HDL cholesterol, and apolipoprotein B in type 2 diabetes in the Collaborative Atorvastatin Diabetes Study (CARDS). Clin Chem. 2009 Mar; 55(3):473-80.
-
Morimoto K, Janssen WJ, Fessler MB, McPhillips KA, Borges VM, Bowler RP, Xiao YQ, Kench JA, Henson PM, Vandivier RW. Lovastatin enhances clearance of apoptotic cells (efferocytosis) with implications for chronic obstructive pulmonary disease. J Immunol. 2006 Jun 15; 176(12):7657-65.
-
Fessler MB, Young SK, Jeyaseelan S, Lieber JG, Arndt PG, Nick JA, Worthen GS. A role for hydroxy-methylglutaryl coenzyme a reductase in pulmonary inflammation and host defense. Am J Respir Crit Care Med. 2005 Mar 15; 171(6):606-15.
-
Tillman JA, Lu F, Goddard LM, Donaldson ZR, Dwinell SC, Tittiger C, Hall GM, Storer AJ, Blomquist GJ, Seybold SJ. Juvenile hormone regulates de novo isoprenoid aggregation pheromone biosynthesis in pine bark beetles, Ips spp., through transcriptional control of HMG-CoA reductase. J Chem Ecol. 2004 Dec; 30(12):2459-94.
-
Kim HJ, Miyazaki M, Man WC, Ntambi JM. Sterol regulatory element-binding proteins (SREBPs) as regulators of lipid metabolism: polyunsaturated fatty acids oppose cholesterol-mediated induction of SREBP-1 maturation. Ann N Y Acad Sci. 2002 Jun; 967:34-42.
-
Stone LM, Tan SS, Tam PP, Finger TE. Analysis of cell lineage relationships in taste buds. J Neurosci. 2002 Jun 01; 22(11):4522-9.
-
Stone LM, Finger TE, Tam PP, Tan SS. Taste receptor cells arise from local epithelium, not neurogenic ectoderm. Proc Natl Acad Sci U S A. 1995 Mar 14; 92(6):1916-20.
|
People  People who have written about this concept. _
Similar Concepts
People who have written about this concept.
_
Top Journals
Top journals in which articles about this concept have been published.
|