 Inteins
"Inteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The internal fragments of precursor proteins (INternal proTEINS) that are autocatalytically removed by PROTEIN SPLICING. The flanking fragments (EXTEINS) are ligated forming mature proteins. The nucleic acid sequences coding for inteins are considered to be MOBILE GENETIC ELEMENTS. Inteins are composed of self-splicing domains and an endonuclease domain which plays a role in the spread of the intein's genomic sequence. Mini-inteins are composed of the self-splicing domains only.
| Descriptor ID |
D047668
|
| MeSH Number(s) |
G02.111.570.060.440
|
| Concept/Terms |
Inteins- Inteins
- Intein
- Protein Introns
- Intervening Protein Sequence
- Intervening Protein Sequences
- Protein Sequence, Intervening
- Protein Sequences, Intervening
- Sequence, Intervening Protein
- Sequences, Intervening Protein
- Introns, Protein
- Intron, Protein
- Protein Intron
|
Below are MeSH descriptors whose meaning is more general than "Inteins".
Below are MeSH descriptors whose meaning is more specific than "Inteins".
This graph shows the total number of publications written about "Inteins" by people in this website by year, and whether "Inteins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 | | 2007 | 1 | 0 | 1 | | 2011 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Inteins" by people in Profiles.
-
Ghosh I, Considine N, Maunus E, Sun L, Zhang A, Buswell J, Evans TC, Xu MQ. Site-specific protein labeling by intein-mediated protein ligation. Methods Mol Biol. 2011; 705:87-107.
-
Malone CL, Boles BR, Horswill AR. Biosynthesis of Staphylococcus aureus autoinducing peptides by using the synechocystis DnaB mini-intein. Appl Environ Microbiol. 2007 Oct; 73(19):6036-44.
-
Sun P, Ye S, Ferrandon S, Evans TC, Xu MQ, Rao Z. Crystal structures of an intein from the split dnaE gene of Synechocystis sp. PCC6803 reveal the catalytic model without the penultimate histidine and the mechanism of zinc ion inhibition of protein splicing. J Mol Biol. 2005 Nov 11; 353(5):1093-105.
|
People  People who have written about this concept. _
Similar Concepts
People who have written about this concept.
_
Top Journals
Top journals in which articles about this concept have been published.
|