 Sulbactam
"Sulbactam" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A beta-lactamase inhibitor with very weak antibacterial action. The compound prevents antibiotic destruction of beta-lactam antibiotics by inhibiting beta-lactamases, thus extending their spectrum activity. Combinations of sulbactam with beta-lactam antibiotics have been used successfully for the therapy of infections caused by organisms resistant to the antibiotic alone.
| Descriptor ID |
D013407
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| MeSH Number(s) |
D02.065.589.099.750.812 D02.886.108.750.812 D03.633.100.300.750.812
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| Concept/Terms |
Sulbactam- Sulbactam
- Penicillanic Acid Sulfone
- Sulfone, Penicillanic Acid
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Below are MeSH descriptors whose meaning is more general than "Sulbactam".
Below are MeSH descriptors whose meaning is more specific than "Sulbactam".
This graph shows the total number of publications written about "Sulbactam" by people in this website by year, and whether "Sulbactam" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 1 | 2 | | 2002 | 1 | 0 | 1 |
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Below are the most recent publications written about "Sulbactam" by people in Profiles.
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Academia EC, Jenrette JE, Mueller SW, McLaughlin JM. Evaluation of First-Dose, Intravenous Push Penicillins and Carbapenems in the Emergency Department. J Pharm Pract. 2022 Jun; 35(3):369-376.
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Gibbs RS, Davies JK, McDuffie RS, Leslie KK, Sherman MP, Centretto CA, Wolf DM. Chronic intrauterine infection and inflammation in the preterm rabbit, despite antibiotic therapy. Am J Obstet Gynecol. 2002 Feb; 186(2):234-9.
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McDuffie RS, Blanton SJ, Charland SL, Gibbs RS. The effect of timing of single-dose transplacental ampicillin-sulbactam therapy for prevention of neonatal group B streptococcal colonization and bacteremia in a rabbit model. Am J Obstet Gynecol. 1996 Aug; 175(2):406-10.
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McDuffie RS, Gibbs RS. Ascending group B streptococcal genital infection in the rabbit model. Am J Obstet Gynecol. 1996 Aug; 175(2):402-5.
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Heddleston L, McDuffie RS, Gibbs RS. A rabbit model for ascending infection in pregnancy: intervention with indomethacin and delayed ampicillin-sulbactam therapy. Am J Obstet Gynecol. 1993 Sep; 169(3):708-12.
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McDuffie RS, Blanton SJ, Shikes RH, Gibbs RS. A rabbit model for bacterially induced preterm pregnancy loss: intervention studies with ampicillin-sulbactam. Am J Obstet Gynecol. 1991 Nov; 165(5 Pt 1):1568-74.
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