 Trifluoroacetic Acid
"Trifluoroacetic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A very strong halogenated derivative of acetic acid. It is used in acid catalyzed reactions, especially those where an ester is cleaved in peptide synthesis.
| Descriptor ID |
D014269
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| MeSH Number(s) |
D02.241.081.018.285.500 D02.455.526.510.286.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Trifluoroacetic Acid".
Below are MeSH descriptors whose meaning is more specific than "Trifluoroacetic Acid".
This graph shows the total number of publications written about "Trifluoroacetic Acid" by people in this website by year, and whether "Trifluoroacetic Acid" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 | | 2016 | 0 | 2 | 2 |
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Below are the most recent publications written about "Trifluoroacetic Acid" by people in Profiles.
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Su H, Liu KY, Karydis A, Abebe DG, Wu C, Anderson KM, Ghadri N, Adatrow P, Fujiwara T, Bumgardner JD. In vitro and in vivo evaluations of a novel post-electrospinning treatment to improve the fibrous structure of chitosan membranes for guided bone regeneration. Biomed Mater. 2016 12 02; 12(1):015003.
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Mant CT, Hodges RS. Separation of Peptides on HALO 2-Micron Particles. Curr Protoc Protein Sci. 2016 08 01; 85:11.6.1-11.6.16.
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Carbain B, Coxon CR, Lebraud H, Elliott KJ, Matheson CJ, Meschini E, Roberts AR, Turner DM, Wong C, Cano C, Griffin RJ, Hardcastle IR, Golding BT. Trifluoroacetic acid in 2,2,2-trifluoroethanol facilitates S(N)Ar reactions of heterocycles with arylamines. Chemistry. 2014 Feb 17; 20(8):2311-7.
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Wei L, Butcher C, Miao Y, Gallazzi F, Quinn TP, Welch MJ, Lewis JS. Synthesis and biologic evaluation of 64Cu-labeled rhenium-cyclized alpha-MSH peptide analog using a cross-bridged cyclam chelator. J Nucl Med. 2007 Jan; 48(1):64-72.
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Mant CT, Hodges RS. Context-dependent effects on the hydrophilicity/hydrophobicity of side-chains during reversed-phase high-performance liquid chromatography: Implications for prediction of peptide retention behaviour. J Chromatogr A. 2006 Sep 01; 1125(2):211-9.
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Shibue M, Mant CT, Hodges RS. Effect of anionic ion-pairing reagent hydrophobicity on selectivity of peptide separations by reversed-phase liquid chromatography. J Chromatogr A. 2005 Jul 01; 1080(1):68-75.
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Shibue M, Mant CT, Hodges RS. The perchlorate anion is more effective than the trifluoroacetate anion as an ion-pairing reagent for reversed-phase chromatography of peptides. J Chromatogr A. 2005 Jul 01; 1080(1):49-57.
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Chen Y, Mehok AR, Mant CT, Hodges RS. Optimum concentration of trifluoroacetic acid for reversed-phase liquid chromatography of peptides revisited. J Chromatogr A. 2004 Jul 16; 1043(1):9-18.
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