 Reserpine
"Reserpine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
| Descriptor ID |
D012110
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| MeSH Number(s) |
D03.132.436.681.933.500 D03.633.100.473.402.681.933.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Reserpine".
Below are MeSH descriptors whose meaning is more specific than "Reserpine".
This graph shows the total number of publications written about "Reserpine" by people in this website by year, and whether "Reserpine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Reserpine" by people in Profiles.
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Redweik GAJ, Kogut MH, Arsenault RJ, Lyte M, Mellata M. Reserpine improves Enterobacteriaceae resistance in chicken intestine via neuro-immunometabolic signaling and MEK1/2 activation. Commun Biol. 2021 12 03; 4(1):1359.
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Margolis KL, Piller LB, Ford CE, Henriquez MA, Cushman WC, Einhorn PT, Colon PJ, Vidt DG, Christian R, Wong ND, Wright JT, Goff DC. Blood pressure control in Hispanics in the antihypertensive and lipid-lowering treatment to prevent heart attack trial. Hypertension. 2007 Nov; 50(5):854-61.
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Battaglino R, Fu J, Sp?te U, Ersoy U, Joe M, Sedaghat L, Stashenko P. Serotonin regulates osteoclast differentiation through its transporter. J Bone Miner Res. 2004 Sep; 19(9):1420-31.
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Nguyen NT, DeGrado TR, Chakraborty P, Wieland DM, Schwaiger M. Myocardial kinetics of carbon-11-epinephrine in the isolated working rat heart. J Nucl Med. 1997 May; 38(5):780-5.
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Rice PJ, Taylor DA, Valinski WA, Head RJ, Fleming WW. Norepinephrine depletion and sensitivity changes in rat heart induced by pretreatment with reserpine. J Pharmacol Exp Ther. 1987 Mar; 240(3):764-71.
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Bero LA, Kuhn CM. Catecholaminergic regulation of opiate-stimulated growth hormone secretion in the developing rat. J Pharmacol Exp Ther. 1986 Apr; 237(1):137-42.
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Goto K, Longhurst PA, Cassis LA, Head RJ, Taylor DA, Rice PJ, Fleming WW. Surgical sympathectomy of the heart in rodents and its effect on sensitivity to agonists. J Pharmacol Exp Ther. 1985 Jul; 234(1):280-7.
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O'Brien RA, Boublik M, Spector S. Immunopharmacological studies using 5-hydroxytryptamine antibody. J Pharmacol Exp Ther. 1975 Jul; 194(1):145-53.
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Reite M, Pegram GV, Stephens LM, Bixler EC, Lewis OL. The effect of reserpine and monoamine oxidase inhibitors on paradoxical sleep in the monkey. Psychopharmacologia. 1969; 14(1):12-7.
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Carlon N, Stahl A. [Experimental study of the cytology of the anterior lobe of the hypophysis in dogs]. C R Seances Soc Biol Fil. 1966; 160(3):578-81.
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