 Microbial Collagenase
"Microbial Collagenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A metalloproteinase which degrades helical regions of native collagen to small fragments. Preferred cleavage is -Gly in the sequence -Pro-Xaa-Gly-Pro-. Six forms (or 2 classes) have been isolated from Clostridium histolyticum that are immunologically cross-reactive but possess different sequences and different specificities. Other variants have been isolated from Bacillus cereus, Empedobacter collagenolyticum, Pseudomonas marinoglutinosa, and species of Vibrio and Streptomyces. EC 3.4.24.3.
| Descriptor ID |
D003012
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| MeSH Number(s) |
D08.811.277.656.300.480.205.500 D08.811.277.656.675.374.205.500
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| Concept/Terms |
Microbial Collagenase- Microbial Collagenase
- Clostridium histolyticum Collagenase
- Collagenase, Clostridium histolyticum
- Nucleolysin
- Collagenase, Microbial
- Collalysine
- Clostridiopeptidase A
- Collagenase Clostridium histolyticum
- Clostridium histolyticum, Collagenase
- histolyticum, Collagenase Clostridium
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Below are MeSH descriptors whose meaning is more general than "Microbial Collagenase".
Below are MeSH descriptors whose meaning is more specific than "Microbial Collagenase".
This graph shows the total number of publications written about "Microbial Collagenase" by people in this website by year, and whether "Microbial Collagenase" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 1 | 0 | 1 |
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Below are the most recent publications written about "Microbial Collagenase" by people in Profiles.
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Shi L, Ermis R, Garcia A, Telgenhoff D, Aust D. Degradation of human collagen isoforms by Clostridium collagenase and the effects of degradation products on cell migration. Int Wound J. 2010 Apr; 7(2):87-95.
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Gupta SK, Gallego C, Johnson GL, Heasley LE. MAP kinase is constitutively activated in gip2 and src transformed rat 1a fibroblasts. J Biol Chem. 1992 Apr 25; 267(12):7987-90.
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Meyer FA, Yaron I, Yaron M. Synergistic, additive, and antagonistic effects of interleukin-1 beta, tumor necrosis factor alpha, and gamma-interferon on prostaglandin E, hyaluronic acid, and collagenase production by cultured synovial fibroblasts. Arthritis Rheum. 1990 Oct; 33(10):1518-25.
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Kandel RA, Petelycky M, Dinarello CA, Minden M, Pritzker KP, Cruz TF. Comparison of the effect of interleukin 6 and interleukin 1 on collagenase and proteoglycan production by chondrocytes. J Rheumatol. 1990 Jul; 17(7):953-7.
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Kandel RA, Dinarello CA, Biswas C. The stimulation of collagenase production in rabbit articular chondrocytes by interleukin-1 is increased by collagens. Biochem Int. 1987 Nov; 15(5):1021-31.
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Rogers G, Martinet N, Steinert P, Wynn P, Roop D, Kilkenny A, Morgan D, Yuspa SH. Cultivation of murine hair follicles as organoids in a collagen matrix. J Invest Dermatol. 1987 Oct; 89(4):369-79.
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Linas SL, Shanley PF, White CW, Parker NP, Repine JE. O2 metabolite-mediated injury in perfused kidneys is reflected by consumption of DMTU and glutathione. Am J Physiol. 1987 Oct; 253(4 Pt 2):F692-701.
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McGregor JA, French JI, Lawellin D, Franco-Buff A, Smith C, Todd JK. Bacterial protease-induced reduction of chorioamniotic membrane strength and elasticity. Obstet Gynecol. 1987 Feb; 69(2):167-74.
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Dayer JM, de Rochemonteix B, Burrus B, Demczuk S, Dinarello CA. Human recombinant interleukin 1 stimulates collagenase and prostaglandin E2 production by human synovial cells. J Clin Invest. 1986 Feb; 77(2):645-8.
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Feddersen CO, McMurtry IF, Henson P, Voelkel NF. Acetylcholine-induced pulmonary vasodilation in lung vascular injury. Am Rev Respir Dis. 1986 Feb; 133(2):197-204.
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