 Receptor, Muscarinic M2
"Receptor, Muscarinic M2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A specific subtype of muscarinic receptor found in the lower BRAIN, the HEART and in SMOOTH MUSCLE-containing organs. Although present in smooth muscle the M2 muscarinic receptor appears not to be involved in contractile responses.
| Descriptor ID |
D043585
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| MeSH Number(s) |
D12.776.543.750.695.475.200 D12.776.543.750.720.360.500.200
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| Concept/Terms |
Receptor, Muscarinic M2- Receptor, Muscarinic M2
- M2 Receptor, Muscarinic
- Muscarinic M2 Receptor
- Receptors, Muscarinic M2
- M2 Receptors, Muscarinic
- Muscarinic M2 Receptors
- Muscarinic Receptor M2
- M2, Muscarinic Receptor
- Receptor M2, Muscarinic
- Muscarinic Receptors M2
- M2, Muscarinic Receptors
- Receptors M2, Muscarinic
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Below are MeSH descriptors whose meaning is more general than "Receptor, Muscarinic M2".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Muscarinic [D12.776.543.750.695.475]
- Receptor, Muscarinic M2 [D12.776.543.750.695.475.200]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Cholinergic [D12.776.543.750.720.360]
- Receptors, Muscarinic [D12.776.543.750.720.360.500]
- Receptor, Muscarinic M2 [D12.776.543.750.720.360.500.200]
Below are MeSH descriptors whose meaning is more specific than "Receptor, Muscarinic M2".
This graph shows the total number of publications written about "Receptor, Muscarinic M2" by people in this website by year, and whether "Receptor, Muscarinic M2" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 | | 2000 | 0 | 1 | 1 | | 2001 | 0 | 1 | 1 | | 2005 | 1 | 0 | 1 | | 2010 | 0 | 1 | 1 | | 2011 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Receptor, Muscarinic M2" by people in Profiles.
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Hendershot CS, Bryan AD, Ewing SW, Claus ED, Hutchison KE. Preliminary evidence for associations of CHRM2 with substance use and disinhibition in adolescence. J Abnorm Child Psychol. 2011 Jul; 39(5):671-81.
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Yang J, Huang J, Maity B, Gao Z, Lorca RA, Gudmundsson H, Li J, Stewart A, Swaminathan PD, Ibeawuchi SR, Shepherd A, Chen CK, Kutschke W, Mohler PJ, Mohapatra DP, Anderson ME, Fisher RA. RGS6, a modulator of parasympathetic activation in heart. Circ Res. 2010 Nov 26; 107(11):1345-9.
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Thapliyal A, Bannister RA, Hanks C, Adams BA. The monomeric G proteins AGS1 and Rhes selectively influence Galphai-dependent signaling to modulate N-type (CaV2.2) calcium channels. Am J Physiol Cell Physiol. 2008 Nov; 295(5):C1417-26.
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Carey MA, Card JW, Bradbury JA, Moorman MP, Haykal-Coates N, Gavett SH, Graves JP, Walker VR, Flake GP, Voltz JW, Zhu D, Jacobs ER, Dakhama A, Larsen GL, Loader JE, Gelfand EW, Germolec DR, Korach KS, Zeldin DC. Spontaneous airway hyperresponsiveness in estrogen receptor-alpha-deficient mice. Am J Respir Crit Care Med. 2007 Jan 15; 175(2):126-35.
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Fryer AD, Stein LH, Nie Z, Curtis DE, Evans CM, Hodgson ST, Jose PJ, Belmonte KE, Fitch E, Jacoby DB. Neuronal eotaxin and the effects of CCR3 antagonist on airway hyperreactivity and M2 receptor dysfunction. J Clin Invest. 2006 Jan; 116(1):228-36.
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Larsen GL, Loader J, Nguyen DD, Fratelli C, Dakhama A, Colasurdo GN. Mechanisms determining cholinergic neural responses in airways of young and mature rabbits. Pediatr Pulmonol. 2004 Aug; 38(2):97-106.
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Evans CM, Jacoby DB, Fryer AD. Effects of dexamethasone on antigen-induced airway eosinophilia and M(2) receptor dysfunction. Am J Respir Crit Care Med. 2001 May; 163(6):1484-92.
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Evans CM, Belmonte KE, Costello RW, Jacoby DB, Gleich GJ, Fryer AD. Substance P-induced airway hyperreactivity is mediated by neuronal M(2) receptor dysfunction. Am J Physiol Lung Cell Mol Physiol. 2000 Sep; 279(3):L477-86.
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Costello RW, Evans CM, Yost BL, Belmonte KE, Gleich GJ, Jacoby DB, Fryer AD. Antigen-induced hyperreactivity to histamine: role of the vagus nerves and eosinophils. Am J Physiol. 1999 05; 276(5):L709-14.
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Evans CM, Fryer AD, Jacoby DB, Gleich GJ, Costello RW. Pretreatment with antibody to eosinophil major basic protein prevents hyperresponsiveness by protecting neuronal M2 muscarinic receptors in antigen-challenged guinea pigs. J Clin Invest. 1997 Nov 01; 100(9):2254-62.
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