Isocitrate Lyase
"Isocitrate Lyase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A key enzyme in the glyoxylate cycle. It catalyzes the conversion of isocitrate to succinate and glyoxylate. EC 4.1.3.1.
| Descriptor ID |
D007522
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| MeSH Number(s) |
D08.811.520.224.600.700
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Isocitrate Lyase".
Below are MeSH descriptors whose meaning is more specific than "Isocitrate Lyase".
This graph shows the total number of publications written about "Isocitrate Lyase" by people in this website by year, and whether "Isocitrate Lyase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2000 | 1 | 0 | 1 |
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Below are the most recent publications written about "Isocitrate Lyase" by people in Profiles.
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McKinney JD, H?ner zu Bentrup K, Mu?oz-El?as EJ, Miczak A, Chen B, Chan WT, Swenson D, Sacchettini JC, Jacobs WR, Russell DG. Persistence of Mycobacterium tuberculosis in macrophages and mice requires the glyoxylate shunt enzyme isocitrate lyase. Nature. 2000 Aug 17; 406(6797):735-8.
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H?ner Zu Bentrup K, Miczak A, Swenson DL, Russell DG. Characterization of activity and expression of isocitrate lyase in Mycobacterium avium and Mycobacterium tuberculosis. J Bacteriol. 1999 Dec; 181(23):7161-7.