 Focal Adhesions
"Focal Adhesions" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An anchoring junction of the cell to a non-cellular substrate. It is composed of a specialized area of the plasma membrane where bundles of the ACTIN CYTOSKELETON terminate and attach to the transmembrane linkers, INTEGRINS, which in turn attach through their extracellular domains to EXTRACELLULAR MATRIX PROTEINS.
| Descriptor ID |
D022001
|
| MeSH Number(s) |
A11.284.149.165.165.285
|
| Concept/Terms |
Focal Adhesions- Focal Adhesions
- Adhesion, Focal
- Adhesions, Focal
- Focal Adhesion
- Focal Contacts
- Contact, Focal
- Contacts, Focal
- Focal Contact
- Adhesion Plaques
- Adhesion Plaque
- Plaque, Adhesion
- Plaques, Adhesion
- Cell-Matrix Adherens Junctions
- Adherens Junction, Cell-Matrix
- Adherens Junctions, Cell-Matrix
- Cell Matrix Adherens Junctions
- Cell-Matrix Adherens Junction
- Junction, Cell-Matrix Adherens
- Junctions, Cell-Matrix Adherens
|
Below are MeSH descriptors whose meaning is more general than "Focal Adhesions".
Below are MeSH descriptors whose meaning is more specific than "Focal Adhesions".
This graph shows the total number of publications written about "Focal Adhesions" by people in this website by year, and whether "Focal Adhesions" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 1 | 2 | | 2004 | 0 | 2 | 2 | | 2005 | 0 | 1 | 1 | | 2006 | 2 | 2 | 4 | | 2008 | 1 | 0 | 1 | | 2009 | 1 | 0 | 1 | | 2010 | 0 | 1 | 1 | | 2011 | 2 | 0 | 2 | | 2012 | 0 | 1 | 1 | | 2013 | 1 | 3 | 4 | | 2014 | 1 | 1 | 2 | | 2015 | 1 | 2 | 3 | | 2016 | 1 | 0 | 1 | | 2017 | 1 | 0 | 1 | | 2018 | 1 | 1 | 2 | | 2019 | 0 | 1 | 1 | | 2020 | 0 | 1 | 1 | | 2021 | 1 | 1 | 2 | | 2022 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Focal Adhesions" by people in Profiles.
-
Tao A, LaCroix AS, Shoyer TC, Venkatraman V, Xu KL, Feiger B, Hoffman BD. Identifying constitutive and context-specific molecular-tension-sensitive protein recruitment within focal adhesions. Dev Cell. 2023 03 27; 58(6):522-534.e7.
-
Han KJ, Mikalayeva V, Gerber SA, Kettenbach AN, Skeberdis VA, Prekeris R. Rab40c regulates focal adhesions and PP6 activity by controlling ANKRD28 ubiquitylation. Life Sci Alliance. 2022 09; 5(9).
-
Jeffrey DA, Pires Da Silva J, Garcia AM, Jiang X, Karimpour-Fard A, Toni LS, Lanzicher T, Pe?a B, Miyano CA, Nunley K, Korst A, Sbaizero O, Taylor MR, Miyamoto SD, Stauffer BL, Sucharov CC. Serum circulating proteins from pediatric patients with dilated cardiomyopathy cause pathologic remodeling and cardiomyocyte stiffness. JCI Insight. 2021 10 08; 6(19).
-
Linklater ES, Duncan ED, Han KJ, Kaupinis A, Valius M, Lyons TR, Prekeris R. Rab40-Cullin5 complex regulates EPLIN and actin cytoskeleton dynamics during cell migration. J Cell Biol. 2021 07 05; 220(7).
-
Blaine J, Dylewski J. Regulation of the Actin Cytoskeleton in Podocytes. Cells. 2020 07 16; 9(7).
-
Furnish M, Caino MC. Altered mitochondrial trafficking as a novel mechanism of cancer metastasis. Cancer Rep (Hoboken). 2020 02; 3(1):e1157.
-
Mason DE, Collins JM, Dawahare JH, Nguyen TD, Lin Y, Voytik-Harbin SL, Zorlutuna P, Yoder MC, Boerckel JD. YAP and TAZ limit cytoskeletal and focal adhesion maturation to enable persistent cell motility. J Cell Biol. 2019 04 01; 218(4):1369-1389.
-
Hoefert JE, Bjerke GA, Wang D, Yi R. The microRNA-200 family coordinately regulates cell adhesion and proliferation in hair morphogenesis. J Cell Biol. 2018 06 04; 217(6):2185-2204.
-
Gong Z, Szczesny SE, Caliari SR, Charrier EE, Chaudhuri O, Cao X, Lin Y, Mauck RL, Janmey PA, Burdick JA, Shenoy VB. Matching material and cellular timescales maximizes cell spreading on viscoelastic substrates. Proc Natl Acad Sci U S A. 2018 03 20; 115(12):E2686-E2695.
-
Wang Q, Delcorde J, Tang T, Downey GP, McCulloch CA. Regulation of IL-1 signaling through control of focal adhesion assembly. FASEB J. 2018 06; 32(6):3119-3132.
|
People  People who have written about this concept. _
Similar Concepts
People who have written about this concept.
_
Top Journals
Top journals in which articles about this concept have been published.
|