Eosinophil Major Basic Protein
"Eosinophil Major Basic Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of several basic proteins released from EOSINOPHIL cytoplasmic granules. Eosinophil major basic protein is a 14-kDa cytotoxic peptide with a pI of 10.9. In addition to its direct cytotoxic effects, it stimulates the release of variety of INFLAMMATION MEDIATORS.
Descriptor ID |
D047093
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MeSH Number(s) |
D12.776.124.486.379.500
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Concept/Terms |
Eosinophil Major Basic Protein- Eosinophil Major Basic Protein
- MBP Protein, Eosinophil
- Eosinophil MBP Protein
- Eosinophil Basic Protein
- Basic Protein, Eosinophil
- Major Basic Protein, Eosinophil
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Below are MeSH descriptors whose meaning is more general than "Eosinophil Major Basic Protein".
Below are MeSH descriptors whose meaning is more specific than "Eosinophil Major Basic Protein".
This graph shows the total number of publications written about "Eosinophil Major Basic Protein" by people in this website by year, and whether "Eosinophil Major Basic Protein" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2005 | 1 | 1 | 2 | 2006 | 0 | 1 | 1 | 2008 | 0 | 1 | 1 | 2009 | 1 | 1 | 2 |
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Below are the most recent publications written about "Eosinophil Major Basic Protein" by people in Profiles.
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Melo RC, Spencer LA, Perez SA, Neves JS, Bafford SP, Morgan ES, Dvorak AM, Weller PF. Vesicle-mediated secretion of human eosinophil granule-derived major basic protein. Lab Invest. 2009 Jul; 89(7):769-81.
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Neves JS, Perez SA, Spencer LA, Melo RC, Weller PF. Subcellular fractionation of human eosinophils: isolation of functional specific granules on isoosmotic density gradients. J Immunol Methods. 2009 May 15; 344(1):64-72.
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Mulder DJ, Pacheco I, Hurlbut DJ, Mak N, Furuta GT, MacLeod RJ, Justinich CJ. FGF9-induced proliferative response to eosinophilic inflammation in oesophagitis. Gut. 2009 Feb; 58(2):166-73.
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Asgari M, Leiferman KM, Piepkorn M, Kuechle MK. Neonatal eosinophilic pustulosis. Int J Dermatol. 2006 Feb; 45(2):131-4.
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Furuta GT, Nieuwenhuis EE, Karhausen J, Gleich G, Blumberg RS, Lee JJ, Ackerman SJ. Eosinophils alter colonic epithelial barrier function: role for major basic protein. Am J Physiol Gastrointest Liver Physiol. 2005 Nov; 289(5):G890-7.
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Melo RC, Perez SA, Spencer LA, Dvorak AM, Weller PF. Intragranular vesiculotubular compartments are involved in piecemeal degranulation by activated human eosinophils. Traffic. 2005 Oct; 6(10):866-79.
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