Carcinoma, Signet Ring Cell
"Carcinoma, Signet Ring Cell" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A poorly differentiated adenocarcinoma in which the nucleus is pressed to one side by a cytoplasmic droplet of mucus. It usually arises in the gastrointestinal system.
| Descriptor ID |
D018279
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| MeSH Number(s) |
C04.557.470.200.025.415 C04.557.470.590.415
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Carcinoma, Signet Ring Cell".
Below are MeSH descriptors whose meaning is more specific than "Carcinoma, Signet Ring Cell".
This graph shows the total number of publications written about "Carcinoma, Signet Ring Cell" by people in this website by year, and whether "Carcinoma, Signet Ring Cell" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 1 | 0 | 1 | | 2013 | 2 | 0 | 2 | | 2014 | 1 | 0 | 1 | | 2016 | 1 | 0 | 1 | | 2018 | 1 | 0 | 1 | | 2019 | 1 | 0 | 1 | | 2020 | 1 | 0 | 1 | | 2021 | 1 | 0 | 1 | | 2022 | 1 | 0 | 1 | | 2023 | 3 | 0 | 3 | | 2024 | 0 | 1 | 1 | | 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Carcinoma, Signet Ring Cell" by people in Profiles.
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Gallanis AF, Gamble LA, Oguz C, Samaranayake SG, Kedei N, Hernandez MO, Wong M, Tillo D, Green BL, McClelland P, Bowden C, Gullo I, Raffeld M, Xi L, Kelly M, Miettinen M, Quezado M, Kim SA, Blakely AM, Lack J, Heller T, Hernandez JM, Davis JL. Spatial Analysis of Hereditary Diffuse Gastric Cancer Reveals Indolent Phenotype of Signet Ring Cell Precursors. Mol Cancer Res. 2025 Aug 04; 23(8):699-709.
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Gallanis AF, Bowden C, Lopez R, Gamble LA, Samaranayake SG, Payne C, Snyder D, Fasaye GA, Joyce S, Broesamle R, Miao N, Miettinen M, Quezado M, Kim SA, Korman L, Heller T, Blakely AM, Hernandez JM, Davis JL. Lessons learned from 150 total gastrectomies for prevention of cancer. J Gastrointest Surg. 2025 Jan; 29(1):101889.
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Green BL, Gamble LA, Diggs LP, Nousome D, Patterson JC, Joughin BA, Gasmi B, Lux SC, Samaranayake SG, Miettinen M, Quezado M, Hernandez JM, Yaffe MB, Davis JL. Early Immune Changes Support Signet Ring Cell Dormancy in CDH1-Driven Hereditary Diffuse Gastric Carcinogenesis. Mol Cancer Res. 2023 12 01; 21(12):1356-1365.
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Samaranayake SG, Gamble LA, Bowden C, Green BL, Gallanis AF, Akbulut D, Shah N, Hernandez JM, Davis JL. Protocol for isolation of signet ring cells from human gastric mucosa. STAR Protoc. 2023 12 15; 4(4):102695.
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Asif B, Sarvestani AL, Gamble LA, Samaranayake SG, Famiglietti AL, Fasaye GA, Quezado M, Miettinen M, Korman L, Koh C, Heller T, Davis JL. Cancer surveillance as an alternative to prophylactic total gastrectomy in hereditary diffuse gastric cancer: a prospective cohort study. Lancet Oncol. 2023 04; 24(4):383-391.
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Gamble LA, Rossi A, Fasaye GA, Kesserwan C, Hernandez JM, Blakely AM, Davis JL. Association Between Hereditary Lobular Breast Cancer Due to CDH1 Variants and Gastric Cancer Risk. JAMA Surg. 2022 01 01; 157(1):18-22.
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Peng T, Yau A, Ding L, David EA, Wightman SC, Atay SM, Kim AW. Primary signet ring cell histology does not portend worse survival for early stage lung cancer following lobectomy. Asian Cardiovasc Thorac Ann. 2022 Feb; 30(2):185-189.
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Holdener SL, Gong Y. Fine-needle aspiration of metastatic melanoma with signet-ring cell features. Diagn Cytopathol. 2021 Oct; 49(10):1138-1140.
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Raghavan SS, Clark M, Louie CY, Jensen KC, Dietrich B, Beadle BM, El-Sawy T, Baik F, Kunder CA, Brown RA. Molecular profiling of a primary cutaneous signet-ring cell/histiocytoid carcinoma of the eyelid. J Cutan Pathol. 2020 Sep; 47(9):860-864.
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Elliott E, Smith A, Moe M, Stolier A, Daroca P, Sholl A, Souers A, Swerdloff H, Duchesne J, Hamner JB. Gastric Outlet Obstruction as an Unusual Presentation for Metastatic Lobular Breast Cancer. Am Surg. 2019 Jul 01; 85(7):e350-e352.
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