Pyrroline Carboxylate Reductases
"Pyrroline Carboxylate Reductases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of enzymes that catalyze the reduction of 1-pyrroline carboxylate to proline in the presence of NAD(P)H. Includes both the 2-oxidoreductase (EC 1.5.1.1) and the 5-oxidoreductase (EC 1.5.1.2). The former also reduces 1-piperidine-2-carboxylate to pipecolate and the latter also reduces 1-pyrroline-3-hydroxy-5-carboxylate to hydroxyproline.
Descriptor ID |
D011762
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MeSH Number(s) |
D08.811.682.662.695
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Pyrroline Carboxylate Reductases".
Below are MeSH descriptors whose meaning is more specific than "Pyrroline Carboxylate Reductases".
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Below are the most recent publications written about "Pyrroline Carboxylate Reductases" by people in Profiles.
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Valle D, Goodman SI, Harris SC, Phang JM. Genetic evidence for a common enzyme catalyzing the second step in the degradation of proline and hydroxyproline. J Clin Invest. 1979 Nov; 64(5):1365-70.