Glycogen Phosphorylase
"Glycogen Phosphorylase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the degradation of GLYCOGEN in animals by releasing glucose-1-phosphate from the terminal alpha-1,4-glycosidic bond. This enzyme exists in two forms: an active phosphorylated form ( PHOSPHORYLASE A) and an inactive un-phosphorylated form (PHOSPHORYLASE B). Both a and b forms of phosphorylase exist as homodimers. In mammals, the major isozymes of glycogen phosphorylase are found in muscle, liver and brain tissue.
| Descriptor ID |
D024981
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| MeSH Number(s) |
D08.811.913.400.450.460.400.186
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Glycogen Phosphorylase".
Below are MeSH descriptors whose meaning is more specific than "Glycogen Phosphorylase".
This graph shows the total number of publications written about "Glycogen Phosphorylase" by people in this website by year, and whether "Glycogen Phosphorylase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Glycogen Phosphorylase" by people in Profiles.
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Nadeau OW, Fontes JD, Carlson GM. The regulation of glycogenolysis in the brain. J Biol Chem. 2018 05 11; 293(19):7099-7107.
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Thwe PM, Pelgrom LR, Cooper R, Beauchamp S, Reisz JA, D'Alessandro A, Everts B, Amiel E. Cell-Intrinsic Glycogen Metabolism Supports Early Glycolytic Reprogramming Required for Dendritic Cell Immune Responses. Cell Metab. 2017 Sep 05; 26(3):558-567.e5.
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Thompson JA, Carlson GM. The regulatory a and ? subunits of phosphorylase kinase directly interact with its substrate, glycogen phosphorylase. Biochem Biophys Res Commun. 2017 Jan 08; 482(2):221-225.