Nitrogen Mustard Compounds
"Nitrogen Mustard Compounds" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of alkylating agents derived from mustard gas, with the sulfur replaced by nitrogen. They were formerly used as toxicants and vesicants, but now function as antineoplastic agents. These compounds are also powerful mutagens, teratogens, immunosuppressants, and carcinogens.
Descriptor ID |
D009588
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MeSH Number(s) |
D02.455.526.728.650
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Nitrogen Mustard Compounds".
Below are MeSH descriptors whose meaning is more specific than "Nitrogen Mustard Compounds".
This graph shows the total number of publications written about "Nitrogen Mustard Compounds" by people in this website by year, and whether "Nitrogen Mustard Compounds" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2011 | 2 | 0 | 2 | 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Nitrogen Mustard Compounds" by people in Profiles.
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Flinn IW, van der Jagt R, Kahl BS, Wood P, Hawkins TE, Macdonald D, Hertzberg M, Kwan YL, Simpson D, Craig M, Kolibaba K, Issa S, Clementi R, Hallman DM, Munteanu M, Chen L, Burke JM. Randomized trial of bendamustine-rituximab or R-CHOP/R-CVP in first-line treatment of indolent NHL or MCL: the BRIGHT study. Blood. 2014 May 08; 123(19):2944-52.
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Mark TM, Reid W, Niesvizky R, Gergis U, Pearse R, Mayer S, Greenberg J, Coleman M, Van Besien K, Shore T. A phase 1 study of bendamustine and melphalan conditioning for autologous stem cell transplantation in multiple myeloma. Biol Blood Marrow Transplant. 2013 May; 19(5):831-7.
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Benito J, Shi Y, Szymanska B, Carol H, Boehm I, Lu H, Konoplev S, Fang W, Zweidler-McKay PA, Campana D, Borthakur G, Bueso-Ramos C, Shpall E, Thomas DA, Jordan CT, Kantarjian H, Wilson WR, Lock R, Andreeff M, Konopleva M. Pronounced hypoxia in models of murine and human leukemia: high efficacy of hypoxia-activated prodrug PR-104. PLoS One. 2011; 6(8):e23108.
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Cancelas JA, Dumont LJ, Rugg N, Szczepiorkowski ZM, Herschel L, Siegel A, Pratt PG, Worsham DN, Erickson A, Propst M, North A, Sherman CD, Mufti NA, Reed WF, Corash L. Stored red blood cell viability is maintained after treatment with a second-generation S-303 pathogen inactivation process. Transfusion. 2011 Nov; 51(11):2367-76.
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Glode AE, Jarkowski A. Bendamustine: a new treatment option for chronic lymphocytic leukemia. Pharmacotherapy. 2009 Nov; 29(11):1375-84.
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Worthen GS, Haslett C, Rees AJ, Gumbay RS, Henson JE, Henson PM. Neutrophil-mediated pulmonary vascular injury. Synergistic effect of trace amounts of lipopolysaccharide and neutrophil stimuli on vascular permeability and neutrophil sequestration in the lung. Am Rev Respir Dis. 1987 Jul; 136(1):19-28.
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Shasby DM, Shasby SS, Bowman CM, Fox RB, Harada RM, Tate RM, Repine JE. Angiotensin converting enzyme concentrations in the lung lavage of normal rabbits and rabbits treated with nitrogen mustard exposed to hyperoxia. Am Rev Respir Dis. 1981 Aug; 124(2):202-3.
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DeShazo CV, McGrade MT, Henson PM, Cochrane CG. The effect of complement depletion on neutrophil migration in acute immunologic arthritis. J Immunol. 1972 May; 108(5):1414-9.
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CONESTABILE E, NATALE P, CERIMELE E. [Nitrogen mustard in rheumatoid arthritis]. Policlinico Prat. 1952 Mar 17; 59(11):333-9.
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